Protein C News and Research

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Quanterix Simoa® Technology Powers Breakthrough Alzheimer’s Disease Research Presented by Eli Lilly and Company at Alzheimer’s Association International Conference (AAIC) 2021

Ultra-sensitive Simoa® HD-X technology powers new findings that detect rapid reduction of plasma P-tau217 from donanemab, Lilly’s investigational antibody therapy for Alzheimer's disease at 12 weeks

From Quanterix 9 Aug 2021

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

In addition to clinical trials conducted to determine the safety and efficacy of the mRNA vaccines, additional studies began describing the serological response to the vaccines under "real-world" conditions, especially with the onset of the SARS-CoV-2 variants and case reports of vaccine escape.

9 Aug 2021

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

The spike protein comprises of two subunits: S1 subunit having the receptor-binding domain (RBD) that helps it to bind to the angiotensin-converting enzyme 2 (ACE2), which is present on the cell surface of the host, and the S2 subunit that helps in the fusion of the cellular membrane and the viral membrane.

9 Aug 2021

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

A group of medications long prescribed to treat tapeworm has inspired a compound that shows two-pronged effectiveness against COVID-19 in laboratory studies, according to a new publication appearing online in the journal ACS Infectious Disease.

9 Aug 2021

Scientists identify calpeptin as potential inhibitor of SARS-CoV-2

A team of US-based scientists has recently conducted a robust high-throughput screening to identify potential entry inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The screening identifies calpeptin as a potent and highly specific inhibitor of SARS-CoV-2 and its variants. The study is currently available on the bioRxiv* preprint server.

9 Aug 2021

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

By retrieving 329,942 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) records from the GISAID database, researchers from a software company in Cambridge described genetic variability of SARS-CoV-2 in order to inform further studies. Their findings are currently available on the bioRxiv* preprint server while it undergoes peer review.

9 Aug 2021

Virus-like particles reveal unexpected mechanism for increased fitness and spread of SARS-CoV-2

Researchers in the United States have developed a new model for testing mutations in the four structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

9 Aug 2021

New phylogenomic platform identifies increased recombination rates in SARS-CoV-2

Researchers in the United States, Australia and the UK have developed a novel method that enables the evolutionary ancestry (phylogeny) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to be comprehensively searched for recombinant lineages.

8 Aug 2021

Long COVID may be due to persistent immune disturbances

A new study discusses abnormalities in the immune response following COVID-19 in samples collected from patients who have recovered from COVID-19.

8 Aug 2021

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

A new study describes the structure of a crucial enzyme present in SARS-CoV-2.

8 Aug 2021

Researchers develop new low-cost reproducible system for co-cultivation of cells

Scientists of the MIPT Cell Signaling Regulation Laboratory have developed a new low cost reproducible system for the co-cultivation of cells. This system is based on a polymerized BSA membrane.

8 Aug 2021

Oral drug found to be effective, safe for treating anemia in patients with chronic kidney disease

Pooled results from recent clinical trials indicate that an oral drug called roxadustat is an effective treatment for anemia in patients with chronic kidney disease.

6 Aug 2021

New tabletop device can quickly detect SARS-CoV-2 from saliva samples

Engineers at MIT and Harvard University have designed a small tabletop device that can detect SARS-CoV-2 from a saliva sample in about an hour.

6 Aug 2021

New immunotherapy strategy can eliminate pancreatic tumors in mice

Pancreatic cancer, which affects about 60,000 Americans every year, is one of the deadliest forms of cancer. After diagnosis, fewer than 10 percent of patients survive for five years.

6 Aug 2021

Light therapy may speed up the healing of burns by activating growth protein

Light therapy may accelerate the healing of burns, according to a University at Buffalo-led study.

6 Aug 2021

New CRISPR-based diagnostic test detects COVID-19 variants from saliva samples

With the Delta variant wreaking havoc on unvaccinated populations and COVID-19 cases spiking around the world, the pandemic is far from over.

6 Aug 2021

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Last year, University of Alabama at Birmingham researchers reported that reductive stress - an imbalance in the normal oxidation/reduction homeostasis - caused pathological changes associated with heart failure in a mouse model.

6 Aug 2021

Study examines the effect of vitamin D supplementation on kidney health in adults with prediabetes

A recent clinical trial described in CJASN has examined the potential of vitamin D supplementation for protecting the kidney health of individuals with pre-diabetes.

6 Aug 2021

Scientists use AI to identify new biomarkers for breast cancer

Scientists at Case Western Reserve University have used Artificial Intelligence (AI) to identify new biomarkers for breast cancer that can predict whether the cancer will return after treatment - and which can be identified from routinely acquired tissue biopsy samples of early-stage breast cancer.

6 Aug 2021

New cargo-carrying nanocontainer constructed entirely from biological components

Nanocontainers can transport substances into cells where they can then take effect. This is the method used in, for example, the mRNA vaccines currently being employed against Covid-19 as well as certain cancer drugs.

6 Aug 2021

Protein C News and Research

Quanterix Simoa® Technology Powers Breakthrough Alzheimer’s Disease Research Presented by Eli Lilly and Company at Alzheimer’s Association International Conference (AAIC) 2021

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

Scientists identify calpeptin as potential inhibitor of SARS-CoV-2

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

Virus-like particles reveal unexpected mechanism for increased fitness and spread of SARS-CoV-2

New phylogenomic platform identifies increased recombination rates in SARS-CoV-2

Long COVID may be due to persistent immune disturbances

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

Researchers develop new low-cost reproducible system for co-cultivation of cells

Oral drug found to be effective, safe for treating anemia in patients with chronic kidney disease

New tabletop device can quickly detect SARS-CoV-2 from saliva samples

New immunotherapy strategy can eliminate pancreatic tumors in mice

Light therapy may speed up the healing of burns by activating growth protein

New CRISPR-based diagnostic test detects COVID-19 variants from saliva samples

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Study examines the effect of vitamin D supplementation on kidney health in adults with prediabetes

Scientists use AI to identify new biomarkers for breast cancer

New cargo-carrying nanocontainer constructed entirely from biological components

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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