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Merits and risks of postmenopausal hormone therapy

The study was categorized as a primary prevention trial for coronary heart disease, although the fact that mean age at recruitment was 63 years was not given enough importance at that time. WHI investigators concluded that hormone therapy (HT) was not cardioprotective, and, in fact, its riskbenefit ratio did not favor the use of postmenopausal hormones for prevention of chronic diseases.

17 May 2007

Link between Parkinson's and narcolepsy

Parkinson's disease is well-known for its progression of motor disorders: stiffness, slowness, tremors, difficulties walking and talking.

17 May 2007

Possible neuroprotective effect of testosterone treatment in men

A small pilot study suggests that testosterone treatment is safe, well tolerated and may reduce symptoms, slow brain degeneration and increase muscle mass in men with relapsing-remitting multiple sclerosis, the most common form of the disease, according to a report in the May issue of Archives of Neurology, one of the JAMA/Archives journals.

17 May 2007

Testosterone gel helps men multiple sclerosis

Close on the heels of a large-scale clinical trial just underway to confirm that the female hormone estriol combats the effects of multiple sclerosis (MS) in women, a just completed pilot study at UCLA now shows promise for the use of testosterone to combat its effects in men.

16 May 2007

Breakthrough in prevention of post-surgical urinary incontinence

Thousands of men facing surgical removal of the prostate due to cancer may someday have one less thing to worry about: post-surgical urinary incontinence.

16 May 2007

Nerves controlling muscles are best repaired with similar nerves

When repairing severed or damaged motor nerves with a donor nerve graft, surgeons have traditionally used a sensory nerve from another area of the patient's body.

16 May 2007

Is the 90-minute deadline for inflation of angioplasty balloons really critical?

In the treatment of heart attack, the 90-minute goal for inflation of an angioplasty balloon in a blocked coronary artery to restore normal blood flow is so revered it's been codified in clinical guidelines, accreditation standards, and pay-for-performance programs.

15 May 2007

Patch to treat Parkinson's gets FDA green light

The Food and Drug Administration (FDA) in the United States has given it's approval for the first patch for Parkinson's disease.

14 May 2007

Most women 55 years and younger who have heart attacks don't recognize warning signs

Women younger than 55 years represent less than 5 percent of all hospitalized heart disease patients, but because so many heart attacks occur in the United State each year, even this small percentage affects a large number of people.

11 May 2007

Omega-3 fatty acids from fish oil may prevent the loss of muscle mass in older people

A research team led by Carole Thivierge, from Universit Laval's Institute of Nutraceutics and Functional Foods, shows that omega-3 fatty acids from fish oil have a positive effect on the metabolism of muscle proteins.

10 May 2007

Discovery of cellular processes which regulate heart's energy supply

The heart needs a steady supply of energy to function properly. MUHC researcher Dr. Vincent Gigure's and his colleagues recently identified several genetic programs which work together to ensure this energy is available.

10 May 2007

Rosuvastatin well tolerated by a broad range of patients with dyslipidemia

The safety and tolerability of rosuvastatin were assessed using data from 16,876 patients who received rosuvastatin 5-40 mg in a multinational phase II/III/IIIb/IV program, representing 25,670 patient-years of continuous exposure to rosuvastatin. An integrated database, consisting of 33 trials whose databases were locked up to and including September 16, 2005, was used to examine adverse events and laboratory data.

9 May 2007

The influence of diluent warming on dantrolene sodium mixing time

Every second counts for anesthesia patients afflicted by the often deadly condition known as malignant hyperthermia (MH).

9 May 2007

Global heartbeat control suggests therapy for beating heart failure

Keeping a healthy heart beating requires the production of a constant supply of energy, a feat depending on the coordination of several genetic programs.

9 May 2007

FluMist may help reduce the burden of seasonal influenza

MedImmune, Inc. has announced research results showing that use of FluMist(R) (Influenza Virus Vaccine Live, Intranasal) in daycare and school settings may help reduce the burden of seasonal influenza.

9 May 2007

Ischemic-targeted approach to angioplasty among asymptomatic survivors of heart attack

When compared with intensive drug therapy, percutaneous coronary intervention (PCI, angioplasty) was more beneficial in reducing the long-term risk of major cardiac events among heart attack survivors with "silent ischemia", according to a study in the May 9 issue of Journal of the American Medical Association.

9 May 2007

Adult stem cells play no role in insulin production

Diabetes researchers, investigating how the body supplies itself with insulin, discovered to their surprise that adult stem cells, which they expected to play a crucial role in the process, were nowhere to be found.

8 May 2007

PET-CT is better for early detection of muscular lymphoma than CT alone

For the study, PET-CT was used to image 305 patients with lymphoma. Twelve of these patients had muscular involvement in which 10 were biopsy proven and two were proven by imaging follow-up.

8 May 2007

Losing weight through calorie cutting won't lead to increased disability in older women

Unintentional weight loss in older adults often leads to frailty, a decline in physical function and even death.

8 May 2007

Heart-assist devices may help some end-stage heart failure patients avoid transplant

Implanted pumps improved heart function enough in a small percentage of patients awaiting a heart transplant that they were able to leave the hospital without a pump and without a new heart, according to a study in Circulation: Journal of the American Heart Association.

8 May 2007