Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

How can we detect cancer and viruses with high sensitivity? Physical chemist Laura Fabris - an associate professor in the Materials Science and Engineering Department at Rutgers, the State University of New Jersey, and principal investigator of the Fabris NanoBio Group - is addressing this very question.

22 May 2018

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth.

17 May 2018

New studies use proteomics to shed light on pathogenic mechanisms

Recent studies in the journal Molecular & Cellular Proteomics have shed light on pathogenic mechanisms of the sexually-transmitted parasite Trichomonas vaginalis and the HIV-associated opportunistic lung fungus Aspergillus.

11 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

New T cell biomarker could be much-needed patient-selection tool for CAR T cell therapy

Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia don't respond to chimeric antigen receptor T cell therapy, and the answer is tied to how primed patients' immune systems are before the therapy is administered.

30 Apr 2018

Innovative research could lead to new ways to treat, prevent cancer

Research into cancer can provide new insight into how this disease works and how it can be stopped. The Experimental Biology 2018 meeting will showcase innovative research that could lead to new ways to treat and prevent cancer.

23 Apr 2018

Experimental compound reduces destructive inflammation to improve stroke outcome

An experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can continue months after a stroke, scientists report.

20 Apr 2018

New breakthrough may allow scientists to orchestrate tissue regeneration in humans

A UNLV scientist and her team have found that frog embryos can fully regrow their eyes after injuries, a breakthrough that may lead one day to the ability to orchestrate tissue regeneration in humans.

19 Apr 2018

Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

Existing microscopy-based methods of detecting apoptosis, such as TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling), have limited quantitative capabilities due to insufficient signal-to-noise ratios.

19 Apr 2018

Scientists decipher mechanism of chemotherapy induced female infertility

Many chemotherapeutics act by damaging the DNA. Since cancer cells divide more often than most normal cells, they react more sensitive to DNA damaging agents.

17 Apr 2018

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Amyotrophic lateral sclerosis is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS.

16 Apr 2018

SYGNIS AG introduces new TruePrime apoptotic cell free DNA amplification kit

SYGNIS AG, the Group which includes Expedeon Holdings, Expedeon, and C.B.S. Scientific Company, today announced the launch of its TruePrime apoptotic cell free DNA amplification kit, under the Expedeon brand.

16 Apr 2018

Resistance training enhances cellular recycling in muscle cells

A new study has shown that resistance training among previously untrained men increases autophagosome content, but that this effect may be blunted by aging.

9 Apr 2018

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis.

2 Apr 2018

Monash scientists discover how gonorrhea-causing superbug evades the immune system

Every year, more than 100 million people worldwide develop the sexually transmitted disease gonorrhea, with health consequences such as infertility, transmission of the disease to newborn babies, and increased risk of HIV infections. There has been a 63 percent rise in gonorrhea in Australia over the past five years.

30 Mar 2018

Scientists discover new family of promising silver-based anti-cancer drugs

A new family of very promising silver-based anti-cancer drugs has been discovered by researchers in South Africa. The most promising silver thiocyanate phosphine complex among these, called UJ3 for short, has been successfully tested in rats and in human cancer cells in the laboratory.

26 Mar 2018

Apoptosis News and Research

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

Scientists discover how unusually long strands of RNA help colon cancer cells avoid death

New studies use proteomics to shed light on pathogenic mechanisms

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

New T cell biomarker could be much-needed patient-selection tool for CAR T cell therapy

Innovative research could lead to new ways to treat, prevent cancer

Experimental compound reduces destructive inflammation to improve stroke outcome

New breakthrough may allow scientists to orchestrate tissue regeneration in humans

Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens

Scientists decipher mechanism of chemotherapy induced female infertility

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

SYGNIS AG introduces new TruePrime apoptotic cell free DNA amplification kit

Resistance training enhances cellular recycling in muscle cells

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Monash scientists discover how gonorrhea-causing superbug evades the immune system

Scientists discover new family of promising silver-based anti-cancer drugs

Viagra cuts colorectal cancer risk in animal model

Cancer initiation found to be similar across organs

Scientists discover the genetic cause of immune disorders

Small molecule plays huge role in keeping people safe from machinations of cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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