Clinical Trial News and Research

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Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD).

15 Jun 2025

Study illustrates a powerful and efficient approach for comparing different standard treatments

A clinical trial led by researchers at The Ottawa Hospital and the University of Ottawa and published in the New England Journal of Medicine illustrates a powerful and efficient approach for comparing different standard treatments.

13 Jun 2025

Boosting CAR T cell survival to improve solid tumor therapy

Chimeric Antigen Receptor (CAR)-T cells are a promising cancer therapy that are made from the patient's own T cells, which are reprogrammed to fight their cancer. One of the limitations of CAR-T cell therapy is the ability of these cells to survive long enough to target the entire tumor.

13 Jun 2025

Empagliflozin preserves kidney function in heart attack patients

SGLT2 inhibitors have become a major drug used to treat diabetes, heart failure, and chronic kidney disease.

13 Jun 2025

New drug combination shows high remission rates in acute myeloid leukemia

A combination therapy that adds a recently approved drug to the current standard of care for newly diagnosed acute myeloid leukemia (AML) showed high rates of complete remission in an early-phase clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and 11 other sites nationwide.

13 Jun 2025

Exercise therapy shows long-term benefits for people with rheumatic diseases

Regular physical activity is increasingly promoted for people with rheumatic and musculoskeletal diseases (RMD) as well as the general population.

13 Jun 2025

Low-dose vitamin D supplements can increase effectiveness of chemotherapy in breast cancer patients

A study conducted at the Botucatu School of Medicine at São Paulo State University (FMB-UNESP) in Brazil has shown that low-dose vitamin D supplementation can increase the effectiveness of chemotherapy treatment in women with breast cancer.

13 Jun 2025

AI and film animation tools lead to breakthrough in coronavirus drug discovery

About 30% of all respiratory tract infections are caused by coronaviruses, leading to widespread illnesses and, in some cases, to epidemic and even pandemic outbreaks, as we experienced with the COVID-19 pandemic.

13 Jun 2025

Telehealth-based care program boosts function and mood in seniors with cancer

New research in the June 2025 issue of JNCCN-Journal of the National Comprehensive Cancer Network found that older people with cancer had better daily functioning, improved mood, stronger illness understanding, and a higher quality of life if they participated in a telehealth-based care program called Geriatric Assessment-Guided Intervention-Supportive Care (GAIN-S).

12 Jun 2025

Digital marker could enhance accuracy of pediatric asthma risk prediction

Researchers at the Indiana University School of Medicine have developed a more accurate and cost-effective method to predict asthma diagnoses in children by using readily available electronic health records.

11 Jun 2025

Extending imaging uncovers hidden stroke-related blood clots

A groundbreaking clinical trial led by London Health Sciences Centre Research Institute (LHSCRI) and Western University's Schulich School of Medicine & Dentistry may enhance how medical professionals detect hidden blood clots responsible for strokes.

11 Jun 2025

Chikungunya vaccine could stop millions of infections worldwide, study finds

A landmark global modeling study reveals that more than 2.8 billion people in 104 countries are at risk of chikungunya, with up to 35 million infections annually. Strategic deployment of the IXCHIQ vaccine could prevent thousands of infections and deaths each year.

11 Jun 2025

Brain interface restores real-time speech for man with ALS

Researchers at the University of California, Davis, have developed an investigational brain-computer interface that holds promise for restoring the voices of people who have lost the ability to speak due to neurological conditions.

11 Jun 2025

New pilot project shows early success in helping cancer survivors return to work

A new pilot project led by McGill University researchers is showing early success in helping cancer survivors return to work, addressing an aspect of recovery they say is often overlooked.

11 Jun 2025

Early intensive therapy shows promise in psoriatic arthritis patients with poor prognostic factors

Is there a benefit to early bDMARD? In psoriatic arthritis (PsA) EULAR - The European Alliance of Associations for Rheumatology - recommends a treat-to-target approach, and suggests more intensive therapy for people with poor prognostic factors, depending on the disease presentation.

11 Jun 2025

New 3D model reveals hidden role of stem cells in sense of smell

Using a newly devised, three-dimensional model to study the regeneration of nerve tissue in the nose, researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) and colleagues have discovered that one type of stem cell thought to be dormant may play a more significant role in preserving the sense of smell than originally believed.

11 Jun 2025

Enhanced Genomics appoints Dietrich Stephan, Ph.D. as Chair of the Board to lead ambitious growth strategy

Enhanced Genomics (‘Enhanced’ or ‘the Company’), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced the appointment of Dietrich Stephan, Ph.D. as Chair of the Board of Directors.

11 Jun 2025

Using causal machine learning to identify potential ALS treatments

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Clinical Trial News and Research

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

Study illustrates a powerful and efficient approach for comparing different standard treatments

Boosting CAR T cell survival to improve solid tumor therapy

Empagliflozin preserves kidney function in heart attack patients

New drug combination shows high remission rates in acute myeloid leukemia

Exercise therapy shows long-term benefits for people with rheumatic diseases

Low-dose vitamin D supplements can increase effectiveness of chemotherapy in breast cancer patients

AI and film animation tools lead to breakthrough in coronavirus drug discovery

Telehealth-based care program boosts function and mood in seniors with cancer

Digital marker could enhance accuracy of pediatric asthma risk prediction

Extending imaging uncovers hidden stroke-related blood clots

Chikungunya vaccine could stop millions of infections worldwide, study finds

Brain interface restores real-time speech for man with ALS

New pilot project shows early success in helping cancer survivors return to work

Early intensive therapy shows promise in psoriatic arthritis patients with poor prognostic factors

New 3D model reveals hidden role of stem cells in sense of smell

Enhanced Genomics appoints Dietrich Stephan, Ph.D. as Chair of the Board to lead ambitious growth strategy

Using causal machine learning to identify potential ALS treatments

Weekly risperidone capsule delivers consistent drug levels for schizophrenia patients

Study reveals a unique vulnerability in melanoma patients with neurofibromin 1 mutations

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