Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Authors of new paper outline possible factors to identify metabolically healthy obesity

Metabolically healthy obesity – where an individual has a Body Mass Index of greater than 30 but does not appear to be at increased risk of the health complications usually associated with excess weight – has only been recently widely recognised by medical practitioners.

3 Sep 2013

Study finds low adiponectin levels prior to pregnancy linked to high risk of gestational diabetes

Overweight women with low levels of the hormone adiponectin prior to pregnancy are nearly seven times more likely to develop gestational diabetes, according to a Kaiser Permanente study published today in the journal Diabetes Care. Adiponectin protects against insulin resistance, inflammation and heart disease.

30 Aug 2013

Genetic variant linked with increased risk of CHD in type 2 diabetic patients

Joslin scientists, in collaboration with researchers from the Harvard School of Public Health and Italian research institutes, have identified a previously unknown genetic variant associated with an increased risk of coronary heart disease (CHD) in type 2 diabetic patients.

28 Aug 2013

Acne and diet: an interview with Dr Katerina Steventon, Research Fellow, HONEI, University of Hull

The typical Western diet tends to have a high glycemic index. High glycemic index foods are e.g. white bread, processed cereals, snacks, cakes and deserts, sweets and also instant foods like burgers and fried chicken.

20 Aug 2013

Researcher receives $3.52 million grant to study epicardial fat in arteries of heart

It's no secret that a diet high in fat and sugar can lead to extra fat around the waistline. But it's what the diet will do to a specific type of fat around the heart that caught the attention of a group of Creighton researchers.

16 Aug 2013

Sanford-Burnham, Pfizer collaborates to identify therapeutic targets for treating obesity, diabetes

Sanford-Burnham Medical Research Institute (Sanford-Burnham) announced that it has entered into a collaboration with Pfizer Inc. to identify new therapeutic targets for preventing and treating complications of obesity and diabetes.

14 Aug 2013

Managing insulin levels through meal timing boosts ovulation in women with PCOS

Polycystic Ovarian Syndrome (PCOS), a common disorder that impairs fertility by impacting menstruation, ovulation, hormones, and more, is closely related to insulin levels. Women with the disorder are typically "insulin resistant" - their bodies produce an overabundance of insulin to deliver glucose from the blood into the muscles.

14 Aug 2013

Vitamin D supplementation does not improve blood pressure in hypertension patients

Vitamin D supplementation does not appear to improve blood pressure or markers of vascular health in older patients with isolated systolic hypertension (a common type of high blood pressure), according to a study by Miles D. Witham, Ph.D., of the University of Dundee, Scotland, United Kingdom, and colleagues.

13 Aug 2013

Exercise could reduce metabolic disease complications in patients post-transplantation

New research reveals that metabolic syndrome—risk factors that can lead to heart disease and/or stroke—is common in liver transplant recipients, with rates highest at one year following the procedure.

7 Aug 2013

Exercise could help reduce metabolic syndrome problems in liver transplant recipients

New research reveals that metabolic syndrome-risk factors that can lead to heart disease and/or stroke-is common in liver transplant recipients, with rates highest at one year following the procedure.

7 Aug 2013

Mothers who breastfeed may have lower risk of Alzheimer's

The report, newly published in the Journal of Alzheimer's Disease, suggests that the link may be to do with certain biological effects of breastfeeding. For example, breastfeeding restores insulin tolerance which is significantly reduced during pregnancy, and Alzheimer's is characterised by insulin resistance in the brain.

6 Aug 2013

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine. The study, conducted in fruit flies and published in the journal Cell, provides insight as to why metabolism-related diseases such as diabetes or obesity are associated with certain types of cancer, including pancreatic, breast, liver, and colon cancers

2 Aug 2013

Glucose intolerance, insulin resistance not associated with pathological features of AD

Glucose intolerance or insulin resistance do not appear to be associated with pathological features of Alzheimer disease (AD) or detection of the accumulation of the brain protein β-amyloid (Αβ), according to a report published by JAMA Neurology, a JAMA Network publication.

30 Jul 2013

FDA acknowledges receipt of NDA resubmission of dapagliflozin drug for treatment of type 2 diabetes

AstraZeneca (NYSE: AZN) and Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has acknowledged receipt of the New Drug Application (NDA) resubmission for investigational drug dapagliflozin for the treatment of adults with type 2 diabetes.

26 Jul 2013

Study shows that eating more eggs is not associated with high serum cholesterol in adolescents

Although in the late 20th century it was maintained that eating more than two eggs a week could increase cholesterol, in recent years experts have begun to refute this myth. Now, a new study has found that eating more eggs is not associated with higher serum cholesterol in adolescents, regardless of how much physical activity they do.

19 Jul 2013

Study examines relationship between religious practices and obesity among Indian immigrants

Asian Indians are one of the fastest growing ethnic groups in the United States, and roughly half a million people of Indian ancestry live in California - more than any other state. Individuals from this group are strongly predisposed to obesity-related conditions such as diabetes and heart disease, due in large part to physical inactivity, diets low in fruit and vegetables, and insulin resistance.

19 Jul 2013

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

These scientists under the leadership of Martin Bilban from the Clinical Institute of Laboratory Medicine at the MedUni Vienna discovered a chain of molecular mechanisms, which is kick-started by the formation of glucocorticoids.

12 Jul 2013

Researchers identify receptor mutation that blocked estrogen action in young woman

A receptor mutation that essentially blocks estrogen's action has been identified for the first time a female, researchers report.

12 Jul 2013

Study shows rates of brain loss caused by aging and AD are higher for women

The rates of regional brain loss and cognitive decline caused by aging and the early stages of Alzheimer's disease (AD) are higher for women and for people with a key genetic risk factor for AD, say researchers at the University of California, San Diego School of Medicine in a study published online July 4 in the American Journal of Neuroradiology.

10 Jul 2013

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

In the constant cross talk between our brain and our gut, two gut hormones are already known to tell the brain when we have had enough to eat. New research suggests that boosting levels of these hormones simultaneously may be an effective new weapon in the fight against obesity.