Neurodegenerative Diseases News and Research

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Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill Cornell Medicine investigators.

14 Apr 2022

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

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11 Apr 2022

Bilingualism can slow down the course of age-related changes in the brain

Medical advances are causing a gradual increase in average life expectancy. However, this comes at a price, as the number of cases of dementia and other neurodegenerative diseases grows with age. Researchers from HSE University (Russia) and Northumbria University (UK) have found that bilingualism can slow down and mitigate the course of age-related changes in the human brain.

11 Apr 2022

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Alzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brain, newly published research argues.

8 Apr 2022

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

New findings from the ongoing Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study suggest that certain rheumatoid arthritis drugs may lower incidence of Alzheimer's disease and related dementias in people with cardiovascular disease.

8 Apr 2022

Researchers discover over 40 new genetic markers for Alzheimer’s disease

A new Nature Genetics study describes over 70 gene markers that appear to be significantly associated with AD risk using translational genomics.

6 Apr 2022

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

Most of us remember enough biology to recall that mitochondria are known as "the powerhouse of the cell." Even that audacious term may downplay the importance of mitochondria and what happens when mitochondria go bad.

31 Mar 2022

Common protein found in neurodegenerative diseases forms amyloid filaments in an age-dependent manner

Experts at Indiana University School of Medicine have helped identify that a common protein found in neurodegenerative diseases forms amyloid filaments in an age-dependent manner without a connection to disease.

29 Mar 2022

Chaperone-mediated autophagy needed to protect against atherosclerosis

Revving up a process that slows down as we age may protect against atherosclerosis, a major cause of heart attacks and strokes.

28 Mar 2022

Rutgers researchers use roundworms to unravel how cells communicate with one another

Scientists have long puzzled about a critical way that cells communicate with one another, but Rutgers researchers have used a simple roundworm to solve the mystery.

25 Mar 2022

Blood biomarker may uniquely aid prediction of dementia in Mexican Americans

Blood levels of a biomarker called glial fibrillary acidic protein (GFAP) may uniquely aid prediction of dementia in Mexican Americans, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and collaborating institutions reported March 24.

24 Mar 2022

Key mechanism that increases drug tolerance among microbial communities revealed

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Intranasal delivery of pro-resolving lipid mediators arrests memory loss in experimental Alzheimer’s model

A research collaboration between scientists at LSU Health New Orleans and the Karolinska Institutet in Sweden has found that applying specialized pro-resolving lipid mediators intranasally arrested memory loss and brain degeneration in an experimental model of Alzheimer's Disease (AD).

21 Mar 2022

A complete transcriptomic analysis of astrocytes in Alzheimer's disease

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

18 Mar 2022

World Sleep Day: Diagnosing chronic respiratory diseases from within the bedroom

For World Sleep Day 2022, News-Medical speaks to Max Sieghold, Co-Founder and CFO of Sleepiz, about their technology and its ability to diagnose sleep apnea/

18 Mar 2022

Insight into oligodendrocytes in the brain could shed light on the causes of neurodegenerative diseases

New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis - and autoimmune disease that affects the brain and nervous system - and allow for the development of better therapeutic treatments.

12 Mar 2022

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

Amyloid beta, a protein known to build up in the brains of people with Alzheimer's disease, also helps skin cancer cells thrive when they spread to the brain, a new study finds.

10 Mar 2022

Damage to general intelligence brain networks makes it difficult for dementia patients to cope with change

People with dementia struggle to adapt to changes in their environment because of damage to areas of the brain known as 'multiple demand networks', highly-evolved areas of the brain that support general intelligence, say scientists at the University of Cambridge.

9 Mar 2022

Stress appears to have a negative effect on the learning of movements in mice

Stress seems to have a negative effect on the learning of movements - at least in mice. This is the conclusion of a recent study at the University of Bonn.

8 Mar 2022

Cell-hobbling fibrils found across diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

4 Mar 2022