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Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

A new research paper was published in Oncotarget's Volume 14 on June 19, 2023, entitled, "Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer."

21 Jun 2023

Study investigates the interplay between acute stress and placebo effects in nausea

Researchers investigated the interplay between acute stress and placebo effects on nausea.

21 Jun 2023

The effect of SGLT2 inhibitors in patients with heart failure and type 2 diabetes

Researchers assessed the impact of SGLT2 inhibitors on type 2 diabetes and heart failure patients in real-world clinical settings.

21 Jun 2023

Treatment with dupilumab leads to sustained improvements in COPD patients with type 2 inflammation

Chronic obstructive pulmonary disease patients with type 2 inflammation saw rapid and sustained improvements in their disease after treatment with the monoclonal antibody dupilumab, according to a yearlong, Phase 3 clinical trial reported in the New England Journal of Medicine.

20 Jun 2023

Exercise is a viable intervention for improving depression and anxiety in young individuals, study finds

Study identifies the best type of exercise for preventing and treating depression in young individuals.

20 Jun 2023

Alcohol-induced psychomotor performance impairment in young adult drinkers with alcohol usage disorders

Researchers examined alcohol-induced psychomotor performance impairments among young adult alcohol consumers with alcohol usage disorders (AUDs).

20 Jun 2023

Smart drugs fall short as cognitive function enhancers

A recent Science Advances study investigated the effectiveness of three popular smart drugs, namely, modafinil (MOD), methylphenidate (MPH), and dextroamphetamine (DEX), against the difficulty of real-life daily tasks, i.e., the 0-1 knapsack optimization problem (“knapsack task”). A knapsack task is basically a combinatorial optimization task, the class of NP-time challenging problems.

18 Jun 2023

Individuals with AUD show psychomotor impairment when challenged with a very high alcohol dose

While heavy drinkers can tolerate a certain amount of alcohol better than light or moderate drinkers, the concept of "holding your liquor" is more nuanced than commonly believed, according to new research from the University of Chicago.

18 Jun 2023

Intravenous treatment with MK-3402 can be an effective strategy in fighting antimicrobial resistance

New research by investigators in Ghent, Belgium shows that intravenous treatment with MK-3402, a metallo-beta-lactamase inhibitor, can be an effective strategy in fighting antimicrobial resistance. The findings are presented at ASM Microbe 2023, the annual meeting of the American Society for Microbiology.

18 Jun 2023

Broader search needed for successful management of eosinophilic gastritis

The good news: a monoclonal antibody treatment called benralizumab proved quite effective in a clinical trial at depleting the number of eosinophils found in the blood and digestive tract tissues of patients with eosinophilic gastritis.

16 Jun 2023

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

Researchers evaluated the prophylactic immune protection conferred by a single intramuscular injection of adintrevimab (ADG20) against symptomatic COVID-19.

16 Jun 2023

$Fruquintinib improved survival in patients with refractory metastatic colorectal cancer$

Fruquintinib improved survival in patients with refractory metastatic colorectal cancer

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer.

16 Jun 2023

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

A new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options.

16 Jun 2023

Bempedoic acid may offer an alternative to the popular cholesterol-lowering drugs

A medication called bempedoic acid reduced the risk of cardiac events as well as statins and may offer an alternative to the popular cholesterol-reducing medications, according to industry-supported research being presented Thursday at ENDO 2023, the Endocrine Society's annual meeting, in Chicago, Ill.

15 Jun 2023

Phase 3 clinical trial shows favorable safety and immunogenicity profile of single-shot live-attenuated chikungunya vaccine

Researchers performed a double-blinded, phase III randomized trial.

15 Jun 2023

Daily multivitamin supplementation has a positive effect on key nutrition biomarkers in older men

A six-month study of healthy older men demonstrated that daily multivitamin/multimineral supplementation had a positive effect on key nutrition biomarkers.

14 Jun 2023

Vaginal seeding engrafts maternal bacteria in the bodies of cesarean section born neonates

Newborns delivered by cesarean section who are swabbed with the vaginal fluid of their mothers after birth have beneficial bacteria restored to their skin surface and stools, according to a new study.

14 Jun 2023

Landmark study in trauma care shines new light on tranexamic acid

A new study from Australia, New Zealand and Germany published in the New England Journal of Medicine raises important questions about the success or otherwise of emergency medicine.

14 Jun 2023

Harm reduction treatment for alcohol use disorder can also reduce the use of other substances

Quitting alcohol or drugs was not a top priority for people experiencing homelessness in a harm reduction treatment study, yet participants still reduced their use of both.

14 Jun 2023

From delicacy to danger: The rising tide of shellfish allergies in children revealed

Shellfish consumption is on the rise, but so are shellfish allergies, particularly among children. A recent review delves into the epidemiology, symptoms, diagnosis, and management of shellfish allergies, highlighting the need for improved diagnostic tools and potential allergen immunotherapy.

13 Jun 2023

Placebo News and Research

Study investigates whether metformin mitigates androgen deprivation therapy-related metabolic syndrome

Study investigates the interplay between acute stress and placebo effects in nausea

The effect of SGLT2 inhibitors in patients with heart failure and type 2 diabetes

Treatment with dupilumab leads to sustained improvements in COPD patients with type 2 inflammation

Exercise is a viable intervention for improving depression and anxiety in young individuals, study finds

Alcohol-induced psychomotor performance impairment in young adult drinkers with alcohol usage disorders

Smart drugs fall short as cognitive function enhancers

Individuals with AUD show psychomotor impairment when challenged with a very high alcohol dose

Intravenous treatment with MK-3402 can be an effective strategy in fighting antimicrobial resistance

Broader search needed for successful management of eosinophilic gastritis

Study concludes a single intramuscular injection of adintrevimab provides prophylactic efficacy against COVID-19 without safety concerns

Fruquintinib improved survival in patients with refractory metastatic colorectal cancer

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

Bempedoic acid may offer an alternative to the popular cholesterol-lowering drugs

Phase 3 clinical trial shows favorable safety and immunogenicity profile of single-shot live-attenuated chikungunya vaccine

Daily multivitamin supplementation has a positive effect on key nutrition biomarkers in older men

Vaginal seeding engrafts maternal bacteria in the bodies of cesarean section born neonates

Landmark study in trauma care shines new light on tranexamic acid

Harm reduction treatment for alcohol use disorder can also reduce the use of other substances

From delicacy to danger: The rising tide of shellfish allergies in children revealed

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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