immunity News and Research

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Prioritizing older individuals for COVID-19 boosters yields best public health outcomes, study finds

Whether prioritizing older individuals for COVID-19 booster vaccinations consistently leads to optimal public health outcomes across diverse socio-economic settings.

13 Aug 2024

Study uncovers OLAH as key driver of fatal respiratory disease

Respiratory infections can be severe, even deadly, in some individuals, but not in others.

12 Aug 2024

New antibody treatment shows promise in preventing heart transplant rejection

A new study from scientists at Cincinnati Children's suggests there may be a way to further protect transplanted hearts from rejection by preparing the donor organ and the recipient with an anti-inflammatory antibody treatment before surgery occurs.

12 Aug 2024

Study reveals how light-activated macrophages increase their appetite for cancer cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

12 Aug 2024

Does cannabis use disorder increase the risk of head and neck cancer?

Researchers determine whether cannabis use disorder increases the risk of head and neck cancer.

12 Aug 2024

Brain circuits connecting stress to gut bacteria reveal new pathways for immune regulation

Researchers have discovered a brain-gut circuit that links stress to changes in gut bacteria, revealing that emotional states can directly influence immune function through the duodenal glands.

11 Aug 2024

Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

Research identifies cross-reactive T cells targeting both SARS-CoV-2 and human SNX8 protein, providing insights into the autoimmune mechanisms driving MIS-C in children.

8 Aug 2024

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced ISM6331, potential best-in-class pan-TEAD inhibitor, has received the U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) clearance for the treatment of mesothelioma, following the grant of Orphan Drug Designation (ODD) in June 2024. It brings the total number of IND-approved molecules of Insilico to nine.

8 Aug 2024

Prenatal famine exposure tied to higher risk of Type 2 diabetes

Researchers at Columbia University Mailman School of Public Health, the University of North Carolina at Chapel Hill and at the National Academy of Sciences of Ukraine used the setting of the man-made Ukrainian Holodomor famine of 1932-1933 to examine the relation between prenatal famine and adult Type 2 diabetes mellitus (T2DM).

8 Aug 2024

Many children with recurrent wheezing have "silent" lung infections, research reveals

Nearly a quarter of children with recurrent wheezing have "silent" lung infections that would be better treated with antiviral medications than commonly prescribed steroids that can carry lifelong side effects, new research from the University of Virginia School of Medicine reveals.

8 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Potential liver risks from popular herbal supplements revealed in new study

A study in JAMA Network Open reveals that 5% of U.S. adults consume six potentially hepatotoxic botanicals, highlighting a significant need for increased regulatory oversight.

6 Aug 2024

INT-1B3 enhances anti-tumor immunity and prolongs survival in mouse models

A new research paper was published in Oncotarget's Volume 15 on July 12, 2024, entitled, "INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death."

5 Aug 2024

Study: Drug-involved overdose deaths increased by over 500% in 2022

Drug-involved overdose deaths increased by over 500 percent in 2022 according to a study at Columbia University Mailman School of Public Health, with trends attributed to synthetic opioids.

5 Aug 2024

Cervical mucus biomarkers could improve early detection of cervical cancer

Cervical cancer is a highly prevalent cancer, with approximately 500,000 new cases diagnosed each year.

5 Aug 2024

Pioneering study brings leishmaniasis vaccine development closer

Scientists have developed a new, safe and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body's immune response, bringing a vaccine for the neglected tropical disease a step closer.

2 Aug 2024

Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense

Researchers discovered diverse and stable immune cell populations in the upper respiratory tract, highlighting the critical role of mucosal immunity in COVID-19 and other respiratory diseases.

1 Aug 2024

Higher urinary metal levels linked to increased cardiovascular risk

Higher levels of urinary metals such as cadmium, tungsten, uranium, cobalt, copper and zinc are linked to increased cardiovascular disease and mortality in a racially and ethnically diverse U.S. population, according to a new study at Columbia University Mailman School of Public Health.

1 Aug 2024

Microbes play key role in carcinogenesis

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world. This includes – as shown in a new study by EMBL researchers and collaborators at the University of Split, Croatia – the way the body responds to carcinogens and develops cancer.

1 Aug 2024

Climate change-driven migrations worsen infectious diseases in vulnerable regions

Climate change-driven migrations increase infectious disease risks by spreading pathogens and overcrowding vulnerable regions, demanding urgent, targeted interventions.

1 Aug 2024

immunity News and Research

Prioritizing older individuals for COVID-19 boosters yields best public health outcomes, study finds

Study uncovers OLAH as key driver of fatal respiratory disease

New antibody treatment shows promise in preventing heart transplant rejection

Study reveals how light-activated macrophages increase their appetite for cancer cells

Does cannabis use disorder increase the risk of head and neck cancer?

Brain circuits connecting stress to gut bacteria reveal new pathways for immune regulation

Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Prenatal famine exposure tied to higher risk of Type 2 diabetes

Many children with recurrent wheezing have "silent" lung infections, research reveals

METRNL protein identified as key player in cancer progression

Potential liver risks from popular herbal supplements revealed in new study

INT-1B3 enhances anti-tumor immunity and prolongs survival in mouse models

Study: Drug-involved overdose deaths increased by over 500% in 2022

Cervical mucus biomarkers could improve early detection of cervical cancer

Pioneering study brings leishmaniasis vaccine development closer

Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense

Higher urinary metal levels linked to increased cardiovascular risk

Microbes play key role in carcinogenesis

Climate change-driven migrations worsen infectious diseases in vulnerable regions

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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