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Malaria elimination and insecticide resistance: an interview with Professor Hilary Ranson, Liverpool School of Tropical Medicine

The first malaria elimination programme was in the 1950s and 1960s. Malaria was eliminated from many countries in Asia and the Americas, largely by indoor spraying with insecticide. But the campaign had very little impact in Africa and eventually resources were moved away from malaria control.

30 Oct 2013

New analysis shows that 29% of clinical trial results remain unpublished

A new analysis of 585 large, randomized clinical trials registered with ClinicalTrials.gov finds that 29 percent have not been published in scientific journals. In addition, nearly 78 percent of the unpublished trials had no results available on the website, either.

30 Oct 2013

Clinical trial finds COREVALVE reduces rate of death, stroke in patients with aortic stenosis

In a clinical trial, a self-expanding transcatheter aortic valve met the key performance objective of reducing death and stroke in patients with severe aortic stenosis at "extreme risk" for surgery.Results of the COREVALVE EXTREME RISK trial were presented today at the 25th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.

30 Oct 2013

Mount Sinai cardiologists use FDA-approved device for severely calcified coronary arteries

Leading interventional cardiologists at The Mount Sinai Hospital are the first in the world to use a newly U.S. Food and Drug Administration approved device for the treatment of severely calcified coronary arteries before the placement of a cardiac stent to open a blocked artery.

29 Oct 2013

Cytrx announces Q3 2013 financial results, provides clinical update

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today reported financial results for the three and nine-month periods ended September 30, 2013, and provided a clinical update.

29 Oct 2013

NEI-funded study explores methods to improve diagnosis, treatment of common eye diseases

If you've ever been sleep-deprived, you've probably had a firsthand glimpse of the blood vessels in your eyes. But what you haven't seen—and what many eye care professionals cannot see as well as they would like—are the vessels closest to the retina, the light-sensitive tissue at the back of the eye.

29 Oct 2013

Viewpoints: Sen. Sanders says don't cut entitlements before making corporations pay taxes; Rep. Smith argues that if entitlements are tamed, other priorities will suffer

Instead of talking about cuts in Social Security, Medicare and Medicaid, we must end the absurdity of corporations not paying a nickel in federal income taxes. A 2008 report from the Government Accountability Office found that was the case with 1 in 4 large U.S. corporations. At a time when multinational corporations and the wealthy are avoiding an estimated $100 billion a year in taxes by stashing money in tax havens like the Cayman Islands, we need to make them pay taxes just as middle-class Americans do (Sen. Bernie Sanders, I-Vt., 10/28).

29 Oct 2013

Patients with psoriatic arthritis benefit from early aggressive drug treatment, says study

People with a type of arthritis affecting the skin and joints respond significantly better to early, aggressive drug treatment compared to standard care, according to preliminary results presented by a University of Leeds lecturer to a major US conference.

29 Oct 2013

Incyte announces results of Phase II clinical trial of oral JAK1 inhibitor in patients with RA

Incyte Corporation (Nasdaq: INCY) announced results from a 12-week, placebo-controlled, dose-escalationin involving 60 patients with active rheumatoid arthritis for its proprietary oral JAK1 inhibitor.

29 Oct 2013

Pulmatrix reports positive results from initial PUR0200 Phase IB clinical study in COPD

Pulmatrix today announced the successful completion and positive results of the first part of a two-part Phase IB clinical study in chronic obstructive pulmonary disease (COPD) patients with their lead clinical candidate PUR0200.

29 Oct 2013

Patellofemoral knee brace can improve pain, bone marrow lesions in knee osteoarthritis patients

Use of a patellofemoral knee brace can improve pain symptoms and bone marrow lesions in patients with a type of osteoarthritis of the knee, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Two aggressive therapy approaches effective for children with juvenile idiopathic arthritis

Children with juvenile idiopathic arthritis who receive early, aggressive therapy with a combination of medications achieve clinical inactive disease status faster than they would with less aggressive therapy, according to new research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Biodesix presents additional VeriStrat Phase III trial data at World Conference on Lung Cancer

Biodesix, Inc., a fully integrated molecular diagnostic company dedicated to personalizing medicine, today announced additional data from the Phase III clinical trial for its serum protein test, VeriStrat. Results were presented at the 15th World Conference on Lung Cancer in Sydney, Australia.

28 Oct 2013

Research: Neurotoxin provides more relief from pain in dogs with bone cancer

By the time bone cancer is diagnosed in a pet dog, it is often too late to save the animal's life. Instead, the goal of treatment is to keep the dog as comfortable and free of pain as possible for as long as possible.

25 Oct 2013

Transcatheter Technologies reports first-in-human implantation of transapical TRINITY aortic valve

Transcatheter Technologies GmbH, a emerging medical device company that is developing a next-generation transcatheter aortic heart valve prosthesis, announced today the successful first-in-human implantation of its transapical TRINITY aortic valve designed to be the world's best repositionable heart valve.

25 Oct 2013

Study finds persistent deficiency in new therapeutics for neglected diseases

In a study published today in the open-access journal The Lancet Global Health, the Drugs for Neglected Diseases initiative and other researchers report a persistent deficiency in truly new therapeutics for neglected diseases, despite nominal progress and an acceleration in research and development efforts. This continued 'fatal imbalance' in medical R&D points to the urgent need to develop and deliver groundbreaking new treatments for the world's poorest and most neglected patients.

25 Oct 2013

Merck provides overview of clinical trial program for HPV vaccine V503

Merck, known as MSD outside the United States and Canada, today provided an overview of the clinical trial program for V503, the company's investigational 9-valent human papillomavirus vaccine, to the Advisory Committee on Immunization Practices in the United States.

25 Oct 2013

MEDIAN Technologies announces participation in World Conference on Lung Cancer

MEDIAN Technologies, a leading medical imaging software solutions developer and a service provider for image interpretation and management in oncology clinical trials and clinical routine, today announced its participation in the World Conference on Lung Cancer, to be held October 27-30, in Sydney, Australia.

24 Oct 2013

New imaging tool could someday be used for routine breast cancer screenings

Breast cancer is one of the most common forms of cancer and cancer deaths among women worldwide. Routine screening can increase breast cancer survival by detecting the disease early and allowing doctors to address it at this critical stage.

23 Oct 2013

Tissue-engineered transplants safe and effective in the long term: Study

New results published in The Lancet today [Wednesday 23 October] reveal that five years after the first successful transplantation of a tissue-engineered airway (reported in The Lancet in 2008) the recipient continues to enjoy a good quality of life, and has not experienced any immunological complications or rejection of the implanted airway.

23 Oct 2013

Clinical Trial News and Research

Malaria elimination and insecticide resistance: an interview with Professor Hilary Ranson, Liverpool School of Tropical Medicine

New analysis shows that 29% of clinical trial results remain unpublished

Clinical trial finds COREVALVE reduces rate of death, stroke in patients with aortic stenosis

Mount Sinai cardiologists use FDA-approved device for severely calcified coronary arteries

Cytrx announces Q3 2013 financial results, provides clinical update

NEI-funded study explores methods to improve diagnosis, treatment of common eye diseases

Viewpoints: Sen. Sanders says don't cut entitlements before making corporations pay taxes; Rep. Smith argues that if entitlements are tamed, other priorities will suffer

Patients with psoriatic arthritis benefit from early aggressive drug treatment, says study

Incyte announces results of Phase II clinical trial of oral JAK1 inhibitor in patients with RA

Pulmatrix reports positive results from initial PUR0200 Phase IB clinical study in COPD

Patellofemoral knee brace can improve pain, bone marrow lesions in knee osteoarthritis patients

Two aggressive therapy approaches effective for children with juvenile idiopathic arthritis

Biodesix presents additional VeriStrat Phase III trial data at World Conference on Lung Cancer

Research: Neurotoxin provides more relief from pain in dogs with bone cancer

Transcatheter Technologies reports first-in-human implantation of transapical TRINITY aortic valve

Study finds persistent deficiency in new therapeutics for neglected diseases

Merck provides overview of clinical trial program for HPV vaccine V503

MEDIAN Technologies announces participation in World Conference on Lung Cancer

New imaging tool could someday be used for routine breast cancer screenings

Tissue-engineered transplants safe and effective in the long term: Study

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