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CAR T-cell therapy enters into Phase I clinical trial

Cancer fighting chimeric antigen receptor (CAR) T cells, developed in the Sentman laboratory of Dartmouth's Norris Cotton Cancer Center, are taking the next step into a Phase I clinical trial beginning early in 2015.

15 Jan 2015

People with iron overload disease are more vulnerable to Vibrio vulnificus infections

Every summer, the news reports on a bacterium called Vibrio vulnificus found in warm saltwater that causes people to get sick, or die, after they eat raw tainted shellfish or when an open wound comes in contact with seawater.

15 Jan 2015

Venom of cone snails provides leads for possible treatment of cancer, addiction

While considered a delicacy in some parts of the world, snails have found a more intriguing use to scientists and the medical profession offering a plethora of research possibilities. Cone snails are marine mollusks, just as conch, octopi and squid, but they capture their prey using venom.

15 Jan 2015

Crown's first European symposium to focus on use of Translational Platforms in oncology drug discovery

Crown Bioscience, Inc., a leading global drug discovery and development service company, has announced its first European symposium, detailing the use of Translational Platforms including Patient-Derived Xenograft (PDX) models in oncology drug discovery and development. The conference will be held on Wednesday 11th February, at the headquarters of One Nucleus in Cambridge, UK and will welcome experts from renowned pharmaceutical companies and prominent academics working in oncology.

15 Jan 2015

TSRI scientists identify novel synthetic compound that reduces activity of a cancer-related protein

Scientists from the Florida campus of The Scripps Research Institute have identified a novel synthetic compound that sharply inhibits the activity of a protein that plays an important role in in the progression of breast and pancreatic cancers.

15 Jan 2015

Lung cancer rates are lower in higher-elevation counties, new study finds

Here's another potential reason to live up in the mountains. Lung cancer rates in both smokers and non-smokers are lower in higher-elevation counties in the western part of the United States, suggesting that oxygen may promote the incidence of lung cancer, according to a new study co-authored by a student at the Perelman School of Medicine at the University of Pennsylvania.

15 Jan 2015

Study: Depression, behavioral changes may occur in Alzheimer's disease before memory declines

Depression and behavioral changes may occur before memory declines in people who will go on to develop Alzheimer's disease, according to new research at Washington University School of Medicine in St. Louis.

14 Jan 2015

Sweetpotato leaves can provide essential vitamins, study finds

Sweetpotato is known to be a good source of ascorbic acid (vitamin C) and certain B vitamins that are considered essential to human health. Besides the commonly consumed root of the plant, certain tissues in sweetpotato are also edible and high in nutritional value. Although studies have confirmed that water-soluble vitamins exist in sweetpotato roots and leaves, there has been limited information about how these vitamins are actually distributed in the plants.

14 Jan 2015

Leading cardiac specialists propose new guidelines for donor heart allocation

A group of leading cardiac specialists has proposed new guidelines for the allocation of donor hearts to patients awaiting transplant. The changes are aimed at improving the organ distribution process to increase the survival rate of patients awaiting transplant and posttransplant.

14 Jan 2015

Neurobiologists find paradoxical effect of abuse-related cues in infants, adults

Neurobiologists at NYU Langone Medical Center and elsewhere have found a surprising and paradoxical effect of abuse-related cues in rat pups: those cues also can lower depressive-like behavior when the rat pups are fully grown.

14 Jan 2015

Sexual objectification can increase women's fears of incurring physical, sexual harm

A study to be published in Sex Roles, published by Springer, offers an explanation for why women fear face-to-face crime more than men, despite being less likely to experience most crimes. The findings by Laurel Watson from the University of Missouri-Kansas City, support the theory that women may have a greater fear of crime due to the potential of also being raped during these encounters.

14 Jan 2015

Universal vaccine against flu may be on the horizon, say researchers

The fact that this year's flu shot is not a good match against this year's influenza strain is well known, and has happened before.

14 Jan 2015

Study finds increase in overall survival in patients with metastatic colorectal cancer

With the dawn of the modern era of new chemotherapeutic and biologic agents available for managing their disease, patients with metastatic colorectal cancer are undergoing less surgery for the removal of their primary tumors, according to research from The University of Texas MD Anderson Cancer Center.

14 Jan 2015

Third annual Food Labs Conference to be held in conjunction with Pittcon 2015

The Pittcon Organizing Committee is pleased to announce the third annual Food Labs Conference, the only food conference focused on the food laboratory, will be held in conjunction with Pittcon 2015, in New Orleans, Louisiana. The co-location of the two conferences provides that the registration fee to attend the two-day Food Lab Conference, March. 9-10, will also include unlimited week long admission to the Pittcon exposition floor and technical program.

14 Jan 2015

Medical co-morbidities associated with direct maternal deaths in the UK

Medical co-morbidities, when women have one or more medical conditions, are found to be an important factor associated with direct maternal deaths, suggests a new study published today (9 January) in BJOG: An International Journal of Obstetrics and Gynaecology (BJOG).

14 Jan 2015

TERT mutations may make smokers more susceptible to emphysema

Mutations in a gene that helps repair damaged chromosome ends may make smokers — especially female smokers — more susceptible to emphysema, according to results of a new study led by Johns Hopkins Kimmel Cancer Center researchers.

14 Jan 2015

Major investment boosts Scotland's gene research

A major investment in gene sequencing technology will secure Scotland's place as a world leader in a genomics revolution that is set to transform healthcare.

14 Jan 2015

Individualized, patient-centered care needed to treat and monitor people with chronic pain

An independent panel convened by the National Institutes of Health concluded that individualized, patient-centered care is needed to treat and monitor the estimated 100 million Americans living with chronic pain. To achieve this aim, the panel recommends more research and development around the evidence-based, multidisciplinary approaches needed to balance patient perspectives, desired outcomes, and safety.

14 Jan 2015

Researchers identify new target that could lead to potential therapies for GBM

Researchers from Virginia Commonwealth University Massey Cancer Center and the VCU Institute for Molecular Medicine have identified a new protein-protein interaction that could serve as a target for future therapies for the most common form of brain cancer, glioblastoma multiforme (GBM).

14 Jan 2015

New article discusses role of cytokines in breast cancer development, progression

Emerging data on the role of inflammation and the immune system in the development, growth, and spread of breast tumors have focused increased attention on the role cytokines such as interleukin and transforming growth factor-β play in breast cancer initiation, protection, and metastasis.

14 Jan 2015

Research News and Research

CAR T-cell therapy enters into Phase I clinical trial

People with iron overload disease are more vulnerable to Vibrio vulnificus infections

Venom of cone snails provides leads for possible treatment of cancer, addiction

Crown's first European symposium to focus on use of Translational Platforms in oncology drug discovery

TSRI scientists identify novel synthetic compound that reduces activity of a cancer-related protein

Lung cancer rates are lower in higher-elevation counties, new study finds

Study: Depression, behavioral changes may occur in Alzheimer's disease before memory declines

Sweetpotato leaves can provide essential vitamins, study finds

Leading cardiac specialists propose new guidelines for donor heart allocation

Neurobiologists find paradoxical effect of abuse-related cues in infants, adults

Sexual objectification can increase women's fears of incurring physical, sexual harm

Universal vaccine against flu may be on the horizon, say researchers

Study finds increase in overall survival in patients with metastatic colorectal cancer

Third annual Food Labs Conference to be held in conjunction with Pittcon 2015

Medical co-morbidities associated with direct maternal deaths in the UK

TERT mutations may make smokers more susceptible to emphysema

Major investment boosts Scotland's gene research

Individualized, patient-centered care needed to treat and monitor people with chronic pain

Researchers identify new target that could lead to potential therapies for GBM

New article discusses role of cytokines in breast cancer development, progression

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