Clinical Trial News and Research

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Researchers develop simple scoring system to predict risk of dementia in older diabetes patients

Researchers have developed a simple scoring system, based on a patient’s age, health issues, and education, which accurately predicts the risk of dementia in people aged over 60 with type 2 diabetes.

20 Aug 2013

Acne and diet: an interview with Dr Katerina Steventon, Research Fellow, HONEI, University of Hull

The typical Western diet tends to have a high glycemic index. High glycemic index foods are e.g. white bread, processed cereals, snacks, cakes and deserts, sweets and also instant foods like burgers and fried chicken.

20 Aug 2013

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Patients with an aggressive lymphoma that often relapses and kills within two years experienced a remission of their cancer and stayed disease-free as long as 28 months after taking a commercially-available drug that made chemotherapy more effective.

20 Aug 2013

Phase III trial evaluates impact of Wisconsin Ginseng on fatigue levels of cancer patients

Millions of cancer patients find themselves exhausted completing the most mundane of tasks, and extra sleep doesn't seem to help. Today, they find hope in a supplement that medical researchers have shown to be effective in boosting their energy levels: Wisconsin Ginseng.

20 Aug 2013

New data analyzing technique via MR imaging identify tumors' response to anti-angiogenesis therapy

A new way of analyzing data acquired in MR imaging appears to be able to identify whether or not tumors are responding to anti-angiogenesis therapy, information that can help physicians determine the most appropriate treatments and discontinue ones that are ineffective.

20 Aug 2013

Clinical trial shows type-1 diabetes patients treated with teplizumab exhibit greater response to therapy

Primary results from a new clinical trial show that patients with type 1 diabetes treated with the monoclonal antibody teplizumab (MacroGenics, Inc.) exhibit greater preservation of C-peptide, a biomarker of islet cell function, compared to controls.

20 Aug 2013

KCI launches new app to help physicians become aware of cutting-edge cancer clinical trials

The Barbara Ann Karmanos Cancer Institute (KCI) today announced its new app to help physicians and healthcare professionals become aware of cutting-edge cancer clinical trials, often available only at Karmanos. The KCI Trials App is free and available on the App Store(SM) for the iPhone and iPad.

19 Aug 2013

FDA grants Orphan Drug Designation to Alnylam ALN-AT3 for treatment of hemophilia B

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that the U.S. Food & Drug Administration (FDA) has granted an Orphan Drug Designation to ALN-AT3 as a therapeutic for the treatment of hemophilia B.

17 Aug 2013

Older heart patients present unique challenges for determining optimal dosages of medications

Older heart patients present unique challenges for determining the optimal dosages of medications, so a new study from researchers at Duke Medicine offers some rare clarity about the use of drugs that are used to treat patients with heart attacks.

17 Aug 2013

Calcium and vitamin D supplements have no effect on joint symptoms in postmenopausal women

A team of investigators systematically analyzed the effect of calcium and vitamin D supplementation on joint symptoms in a rigorous and controlled study of postmenopausal women. They found that supplementation did not reduce the severity of joint symptoms reported by the participants.

17 Aug 2013

DLBCLs resistant to chemotherapy can be reprogrammed to respond using azacitidine

A phase I clinical trial showed diffuse, large B-cell lymphomas (DLBCLs) resistant to chemotherapy can be reprogrammed to respond to treatment using the drug azacitidine, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

17 Aug 2013

BIDMC cardiovascular research team receives $4M grant to identify mRNA biomarkers in heart disease

A cardiovascular research team from Beth Israel Deaconess Medical Center (BIDMC) and Brigham and Women's Hospital (BWH), led by BIDMC Principal Investigator Saumya Das, MD, PhD, has been awarded a $4 million Common Fund grant from the National Institutes of Health (NIH) as part of a newly formed program on Extracellular RNA Communication.

17 Aug 2013

New remote monitoring platform fulfills FDA's guidance on remote, central and risk-based monitoring

The ROMaN Project, Inc. announces its endorsement of the Food and Drug Administration's (FDA) guidance to utilize risk-based monitoring in clinical trials. Risk-based monitoring focuses attention to the most critical data elements in a study and allocates monitoring resources to the investigator sites with problematic or unproven protocol compliance and/or data integrity.

16 Aug 2013

Phase II trial to investigate vaccine therapy combined with Avastin for patients with recurrent GBM

Northwestern Medicine- recently joined a landmark clinical trial to investigate if a vaccine made from a patient's own brain tumor is effective in slowing tumor progression and extending survival.

16 Aug 2013

Surgeons evaluate combined surgery technique to remove cancerous tumors from rectum

Surgeons at the University of California, San Diego School of Medicine are evaluating a new, combined surgery technique to remove cancerous tumors from the rectum. The hybrid technique uses the body's natural opening to remove malignancies and diseased tissue while also performing reconstruction.

16 Aug 2013

Six months of intravenous fish oil reverses pediatric intestinal failure associated liver disease

Children who suffer from intestinal failure, most often caused by a shortened or dysfunctional bowel, are unable to consume food orally. Instead, a nutritional cocktail of sugar, protein and fat made from soybean oil is injected through a small tube in their vein.

16 Aug 2013

Clinical Trial News and Research

Researchers develop simple scoring system to predict risk of dementia in older diabetes patients

Acne and diet: an interview with Dr Katerina Steventon, Research Fellow, HONEI, University of Hull

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Phase III trial evaluates impact of Wisconsin Ginseng on fatigue levels of cancer patients

New data analyzing technique via MR imaging identify tumors' response to anti-angiogenesis therapy

Clinical trial shows type-1 diabetes patients treated with teplizumab exhibit greater response to therapy

KCI launches new app to help physicians become aware of cutting-edge cancer clinical trials

FDA grants Orphan Drug Designation to Alnylam ALN-AT3 for treatment of hemophilia B

Older heart patients present unique challenges for determining optimal dosages of medications

Calcium and vitamin D supplements have no effect on joint symptoms in postmenopausal women

DLBCLs resistant to chemotherapy can be reprogrammed to respond using azacitidine

BIDMC cardiovascular research team receives $4M grant to identify mRNA biomarkers in heart disease

New remote monitoring platform fulfills FDA's guidance on remote, central and risk-based monitoring

Phase II trial to investigate vaccine therapy combined with Avastin for patients with recurrent GBM

Surgeons evaluate combined surgery technique to remove cancerous tumors from rectum

Six months of intravenous fish oil reverses pediatric intestinal failure associated liver disease

Joint symptoms in postmenopausal women not reduced by calcium and vitamin D supplements

Sugar offers noninvasive way to precisely image tumors through new imaging technology

Hitting treadmill today won't help you sleep tonight; it takes 4 months to kick in

Neuroimaging specialists use tanners to identify whether UV light triggers brain's pleasure sensors

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