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Added benefit of daclatasvir drug not proven for chronic hepatitis C infection

The drug daclatasvir (trade name Daklinza) has been available since August 2014 for the treatment of adults with chronic hepatitis C (CHC) infection. The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this new drug offers an added benefit over the appropriate comparator therapy.

11 Dec 2014

Johns Hopkins study shows gene expression in autism brains

While many different combinations of genetic traits can cause autism, brains affected by autism share a pattern of ramped-up immune responses, an analysis of data from autopsied human brains reveals. The study, a collaborative effort between Johns Hopkins and the University of Alabama at Birmingham, included data from 72 autism and control brains.

11 Dec 2014

Alcohol consumption interferes with sleep homeostasis

Researchers from the University of Missouri School of Medicine have found that drinking alcohol to fall asleep interferes with sleep homeostasis, the body's sleep-regulating mechanism.

11 Dec 2014

New study reveals how COX-2 inhibitors can increase risk of heart attack in arthritis patients

A class of drug for treating arthritis - all but shelved over fears about side effects - may be given a new lease of life, following the discovery of a possible way to identify which patients should avoid using it.

11 Dec 2014

Silvia Jurisson recognized as AAAS Fellow for contributions to cancer research

Nuclear medicine is the branch of medicine that uses radioactive materials to provide diagnostics and treatments for cancer. Often, standard protocols involve using radioactive isotopes developed to image as well as weaken cancer cells in the body. With more than 30 years of research in radiopharmaceutical chemistry, Silvia Jurisson, a researcher at the University of Missouri, is a world-renowned scientist who continues to develop breakthrough materials used in the detection and treatment of cancer.

11 Dec 2014

$Golden Jubilee National Hospital first to use revolutionary technology in rib fracture surgery$

Golden Jubilee National Hospital first to use revolutionary technology in rib fracture surgery

The Golden Jubilee National Hospital recently became the first hospital in Scotland to use a revolutionary new technology on a patient suffering from a severe rib fracture.

11 Dec 2014

UTHealth opens Trauma and Grief Center for Youth

Children who are having difficulty processing trauma or loss can now turn to the Trauma and Grief Center for Youth at The University of Texas Health Science Center at Houston.

10 Dec 2014

Reductions in government healthcare spending in the EU linked to increased maternal mortality rates

Reductions in government healthcare spending in the European Union are associated with increased maternal mortality rates, suggests a new paper published today (10 December) in BJOG: An International Journal of Obstetrics and Gynaecology. However, if skilled birth attendants are in place, the association disappears, highlighting the potential importance of maternal care, finds the research.

10 Dec 2014

Arrhythmia patients who manage lifestyle factors more likely to have long-term survival

Patients suffering from the world's most common heart rhythm disorder can have their long-term outcomes significantly improved with an aggressive management of their underlying cardiac risk factors, according to University of Adelaide researchers.

10 Dec 2014

Simple supplement could reduce heart disease in individuals born with low birth weight

A simple supplement could be a safe and cost-effective way of reducing heart disease in individuals born with a low birth weight, suggests research from the University of Cambridge. The study, carried out in rats, also raises the possibility of developing a blood test to indicate how much damage there is in the aortas of these individuals.

10 Dec 2014

Cancer Council urges partners of men diagnosed with prostate cancer to reach out for support

Cancer Council is calling on partners of men with prostate cancer to reach out for support, with research showing partners experience high levels of distress related to the diagnosis of their loved one.

10 Dec 2014

Study brings researchers closer to understanding how brains work

Whether we're paying attention to something we see can be discerned by monitoring the firings of specific groups of brain cells. Now, new work from Johns Hopkins shows that the same holds true for the sense of touch. The study brings researchers closer to understanding how animals' thoughts and feelings affect their perception of external stimuli.

10 Dec 2014

Myriad Genetics highlights three new studies at SABCS 2014

Myriad Genetics, Inc. today announced results from a new study that demonstrated the ability of the myRisk Hereditary Cancer test to detect 105 percent more mutations in cancer causing genes than conventional BRCA testing alone. The Company also presented two key studies in triple negative breast cancer (TNBC) that show the myChoice HRD test accurately predicted response to platinum-based therapy in patients with early-stage TNBC and that the BRACAnalysis molecular diagnostic test significantly predicted response to platinum-based drugs in patients with metastatic TNBC.

10 Dec 2014

Study: Long-term endurance training alters epigenetic pattern in the human skeletal muscle

A new study from Karolinska Institutet in Sweden shows that long-term endurance training in a stable way alters the epigenetic pattern in the human skeletal muscle. The research team behind the study, which is being published in the journal Epigenetics, also found strong links between these altered epigenetic patterns and the activity in genes controlling improved metabolism and inflammation.

10 Dec 2014

Scientists develop new technique to get detailed images of mouse neurons

Scientists can now explore nerves in mice in much greater detail than ever before, thanks to an approach developed by scientists at the European Molecular Biology Laboratory in Monterotondo, Italy. The work, published online today in Nature Methods, enables researchers to easily use artificial tags, broadening the range of what they can study and vastly increasing image resolution.

10 Dec 2014

Variations in ERAP1 enzyme could lead to Ankylosing Spondylitis

Scientists at the University of Southampton have discovered variations in an enzyme belonging to the immune system that leaves individuals susceptible to Ankylosing Spondylitis.

10 Dec 2014

Genetic variations may contribute to treatment-related cognitive problems in children with ALL

Common variations in four genes related to brain inflammation or cells' response to damage from oxidation may contribute to the problems with memory, learning and other cognitive functions seen in children treated for acute lymphoblastic leukemia (ALL), according to a study led by researchers from Boston Children's Hospital, The Children's Hospital at Montefiore, and Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

10 Dec 2014

Use of HF-WBI for patients with early-stage breast cancer increases 17.4%, study finds

The use of hypofractionated whole-breast irradiation (HF-WBI) for patients with early-stage breast cancer increased 17.4 percent from 2004 to 2011, and patients are more likely to receive HF-WBI compared to conventionally fractionated whole-breast irradiation (CF-WBI) when they are treated at an academic center or live ≥50 miles away from a cancer center, according to a study published in the December 1, 2014 issue of the International Journal of Radiation Oncology • Biology • Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology.

10 Dec 2014

E-cigarettes not as addictive as tobacco cigarettes

E-cigarettes appear to be less addictive than cigarettes in former smokers and this could help improve understanding of how various nicotine delivery devices lead to dependence, according to researchers.

10 Dec 2014

Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Long known for its ability to help organisms successfully adapt to environmentally stressful conditions, the highly conserved molecular chaperone heat-shock protein 90 (HSP90) also enables estrogen receptor-positive (ER+) breast cancers to develop resistance to hormonal therapy.

10 Dec 2014

Research News and Research

Added benefit of daclatasvir drug not proven for chronic hepatitis C infection

Johns Hopkins study shows gene expression in autism brains

Alcohol consumption interferes with sleep homeostasis

New study reveals how COX-2 inhibitors can increase risk of heart attack in arthritis patients

Silvia Jurisson recognized as AAAS Fellow for contributions to cancer research

Golden Jubilee National Hospital first to use revolutionary technology in rib fracture surgery

UTHealth opens Trauma and Grief Center for Youth

Reductions in government healthcare spending in the EU linked to increased maternal mortality rates

Arrhythmia patients who manage lifestyle factors more likely to have long-term survival

Simple supplement could reduce heart disease in individuals born with low birth weight

Cancer Council urges partners of men diagnosed with prostate cancer to reach out for support

Study brings researchers closer to understanding how brains work

Myriad Genetics highlights three new studies at SABCS 2014

Study: Long-term endurance training alters epigenetic pattern in the human skeletal muscle

Scientists develop new technique to get detailed images of mouse neurons

Variations in ERAP1 enzyme could lead to Ankylosing Spondylitis

Genetic variations may contribute to treatment-related cognitive problems in children with ALL

Use of HF-WBI for patients with early-stage breast cancer increases 17.4%, study finds

E-cigarettes not as addictive as tobacco cigarettes

Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

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