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Case Western Reserve selected to lead $27.3 million international effort to identify causes of SUDEP

Case Western Reserve is one of two universities in the country selected to lead a $27.3 million international effort to identify the causes of a mysterious and deadly phenomenon that strikes people with epilepsy without warning.

9 Dec 2014

Triple hormone reduces body weight, improves insulin sensitivity

Recently, the researchers had constructed several single molecules with dual hormone action. Now, for the first time, the researchers succeeded in designing a substance that combines three metabolically active hormone components (GLP-1, GIP and glucagon) and offers unmatched potency to fight metabolic diseases in pre-clinical trials.

9 Dec 2014

Adverse childhood experiences impact child health, school outcomes

Nearly half of all children in the United States are exposed to at least one social or family experience that can lead to traumatic stress and impact their healthy development - be it having their parents divorce, a parent die or living with someone who abuses alcohol or drugs - increasing the risk of negative long-term health consequences or of falling behind in school, suggests new research led by the Johns Hopkins Bloomberg School of Public Health.

9 Dec 2014

Study shows seasonal flu vaccines may protect individuals against many different viruses

Seasonal flu vaccines may protect individuals not only against the strains of flu they contain but also against many additional types, according to a study published this week in mBio, the online open-access journal of the American Society for Microbiology.

9 Dec 2014

Children living in non-redeveloped public housing more likely to take repeated trips to emergency rooms

San Francisco children living in non-redeveloped public housing are 39 percent more likely to repeatedly visit emergency rooms, according to new research from UC San Francisco and UC Berkeley.

9 Dec 2014

Better planning needed to improve mother-infant outcomes in hospitals, say CHOP researchers

What does it mean for expectant mothers and hospitals when there are large-scale closures of maternity units? A new study led by researchers at The Children's Hospital of Philadelphia provides an inside view from hospital staff members in Philadelphia, where 13 out of 19 obstetric units closed in a 15-year period.

9 Dec 2014

Smoking can inhibit success of alcohol abuse treatment, new study finds

A new study has shown that smoking can inhibit the success of treatment for alcohol abuse, putting people who are addicted to both tobacco and alcohol in a double bind.

9 Dec 2014

Experts launch new interdisciplinary scientific collaboration to improve health in urban areas

Aiming to empower planners and policy-makers to achieve better health for billions of people living in fast-growing urban areas, world health, environmental, behavioural and social science experts today launched a major new interdisciplinary scientific collaboration.

9 Dec 2014

Amgen announces new data from BLINCYTO Phase 2 study for treatment of patients with ALL

Amgen today announced that new data from a pivotal Phase 2 study evaluating BLINCYTO (blinatumomab) for the treatment of adult patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia (ALL) was presented at the 56th American Society of Hematology Annual Meeting and Exposition.

9 Dec 2014

Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Results from the Phase 2 RESONATE-17 (PCYC-1117) study show IMBRUVICA (ibrutinib) was associated with an 82.6 percent investigator-assessed overall response rate (ORR; the primary endpoint) and a 79 percent progression-free survival (PFS) rate at 12 months in people living with relapsed/refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have a genetic mutation known as deletion 17p (del 17p).

9 Dec 2014

Nationwide Children's Hospital receives ANCC Magnet Recognition for third time

The American Nurses Credentialing Center's Magnet Recognition Program for excellence in nursing services has granted Nationwide Children's Hospital ANCC Magnet Recognition for a third time. This prestigious recognition is the ultimate benchmark in nursing excellence and is awarded to only about seven percent of the nation's more than 6,000 hospitals across the country.

8 Dec 2014

PRM-151 compound shows positive results for treating advanced myelofibrosis

A study that investigated the potential of the compound PRM-151 (PRM) for reducing progressive bone marrow fibrosis (scarring) in patients with advanced myelofibrosis has shown initial positive results. Myelofibrosis is a life-threatening bone marrow cancer.

8 Dec 2014

UTHealth receives $7.3 million grant to research on health information technology

The University of Texas Health Science Center at Houston School of Biomedical Informatics has been awarded grants totaling $7.3 million to enhance health care and biomedical discovery through the use of health information technology.

8 Dec 2014

McMaster University researchers identify hormone that contributes to obesity, diabetes

Researchers from McMaster University have identified an important hormone that is elevated in obese people and contributes to obesity and diabetes by inhibiting brown fat activity.

8 Dec 2014

Screening system spots cancerous changes invisible to sequencing

A technique that can identify causes of cancer invisible to genetic sequencing has uncovered large sets of previously unknown pancreatic cancer genes. It is hoped that this study will boost research into a disease that is still poorly understood and for which five-year survival rates have stood at around 5 per cent for the past four decades.

8 Dec 2014

Findings open new avenues for research to predict risk of therapy-related AML

For a small percentage of cancer patients, treatment aimed at curing the disease leads to a form of leukemia with a poor prognosis. Conventional thinking goes that chemotherapy and radiation therapy induce a barrage of damaging genetic mutations that kill cancer cells yet inadvertently spur the development of acute myeloid leukemia (AML), a blood cancer.

8 Dec 2014

Study highlights causes of postpartum disorders in new mothers

In the days shortly after giving birth, most mothers experience a period of increased calmness and decreased stress responses, but around 20% of mothers experience anxiety. Some women may become depressed, and around one in a thousand can develop psychosis. The latest evidence indicates that these distressing responses to motherhood are still poorly understood, but that animal research could provide valuable clues to their causes.

8 Dec 2014

Rutgers researcher receives NIH grant to develop rapid test to diagnose Ebola

Rutgers researcher David Alland, working with the California biotechnology company Cepheid, has received a grant of nearly $640,000 from the National Institutes of Health to develop a rapid test to diagnose Ebola as well as other viruses that can cause symptoms similar to Ebola.

8 Dec 2014

Low doses of fluoxetine could hold key to preventing PMS symptoms

Low doses of fluoxetine - better known as the anti-depressant Prozac - could hold the key to preventing PMS symptoms, an international team of researchers has found.

8 Dec 2014

Older Latinos living in safe, walkable neighborhoods less likely to develop severe depressive symptoms

Older Latinos living in the U.S. who perceive their neighborhoods as safer and more walkable are less likely to develop severe depressive symptoms, and the effect may be long term, a new study suggests.

8 Dec 2014

Research News and Research

Case Western Reserve selected to lead $27.3 million international effort to identify causes of SUDEP

Triple hormone reduces body weight, improves insulin sensitivity

Adverse childhood experiences impact child health, school outcomes

Study shows seasonal flu vaccines may protect individuals against many different viruses

Children living in non-redeveloped public housing more likely to take repeated trips to emergency rooms

Better planning needed to improve mother-infant outcomes in hospitals, say CHOP researchers

Smoking can inhibit success of alcohol abuse treatment, new study finds

Experts launch new interdisciplinary scientific collaboration to improve health in urban areas

Amgen announces new data from BLINCYTO Phase 2 study for treatment of patients with ALL

Phase 2 RESONATE-17 study: IMBRUVICA (ibrutinib) improves survival in CLL patients with del 17p

Nationwide Children's Hospital receives ANCC Magnet Recognition for third time

PRM-151 compound shows positive results for treating advanced myelofibrosis

UTHealth receives $7.3 million grant to research on health information technology

McMaster University researchers identify hormone that contributes to obesity, diabetes

Screening system spots cancerous changes invisible to sequencing

Findings open new avenues for research to predict risk of therapy-related AML

Study highlights causes of postpartum disorders in new mothers

Rutgers researcher receives NIH grant to develop rapid test to diagnose Ebola

Low doses of fluoxetine could hold key to preventing PMS symptoms

Older Latinos living in safe, walkable neighborhoods less likely to develop severe depressive symptoms

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