Therapy News and Research

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UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Dr. Camilo Ricordi, director of the Diabetes Research Institute and Cell Transplant Center at the University of Miami Miller School of Medicine, and his team of international collaborators are reporting the results of a groundbreaking randomized controlled trial showing umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions safely reduce risk of death and quicken time to recovery for the most severe COVID-19 patients.

5 Jan 2021

Researchers receive $2.1 million NIH grant to study causes of congenital heart defects

Congenital heart defects are the most common type of birth defect, affecting nearly 1% of births in the United States each year, according to the Centers for Disease Control. Doctors have been unable to lower that number due to a lack of knowledge about their source.

5 Jan 2021

Mid-term clinical trial results of two cell therapies for critical limb ischemia show similar outcomes

Mid-term results of the first clinical trial designed specifically to evaluate the safety and effectiveness of two cell therapies that are showing early promise in treating angiitis-induced critical limb ischemia were released today in STEM CELLS Translational Medicine.

5 Jan 2021

NCCN publishes new informational resources on health and wellness for cancer survivors

Today, the National Comprehensive Cancer Network announced the publication of new, free informational resources on health and wellness for cancer survivors.

5 Jan 2021

Researchers apply AI to help physicians customize treatments for patients with oral cancers

Researchers at Case Western Reserve University and partners in the United States and India are applying the investigative and predictive capabilities of artificial intelligence (AI) to help physicians customize treatments for patients with oral squamous cell carcinomas.

5 Jan 2021

Non-invasive technique can provide accurate prognosis in unresponsive brain injury patients

Assessing the ability of unresponsive patients with severe brain injury to understand what is being said to them could yield important insights into how they might recover, according to new research.

5 Jan 2021

Repeated ketamine infusions may be a promising treatment for PTSD patients

Repeated intravenous (IV) ketamine infusions significantly reduce symptom severity in individuals with chronic post-traumatic stress disorder (PTSD) and the improvement is rapid and maintained for several weeks afterwards, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai.

5 Jan 2021

Heat treatment during chemotherapy is more effective at destroying cancer cells

Heating up cancer cells while targeting them with chemotherapy is a highly effective way of killing them, according to a new study led by UCL researchers.

5 Jan 2021

Replacing the RNA strand with DNA may enhance efficacy of ASO-based drugs

Antisense oligonucleotides (ASO) hold great promise for pharmacotherapy. Now, researchers at Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, advancing their earlier work on a heteroduplex oligonucleotide (HDO) model, have demonstrated augmentation of ASO-based drugs by replacing the RNA strand with DNA.

5 Jan 2021

Study investigates the total non-healthcare cost of chemotherapy

Chemotherapy for breast cancer costs the UK economy more than £248 million annually, including 'out-of-pocket' personal costs of more than £1,000 per patient - according to new research from the University of East Anglia.

4 Jan 2021

Researchers develop a gene signature for predicting survival in patients with peritoneal carcinomatosis

Researchers from The University of Texas MD Anderson Cancer Center who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patient survival.

4 Jan 2021

Experts assess the impact of COVID-19 on pediatric patients with special needs

The impact of the COVID-19 pandemic on children with disabilities has not received much attention, perhaps because the disease disproportionately affects older individuals.

4 Jan 2021

Inflammation marker linked to increased fatigue in prostate cancer patients treated with ADT

Prostate cancer is one of the most common cancers among men in the U.S. For many patients, hormone therapy is a treatment option.

4 Jan 2021

Six clearly distinguishable subtypes of prediabetes identified

All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary diseases.

4 Jan 2021

Tissue healing after brain injury could spur tumor growth

The healing process that follows a brain injury could spur tumor growth when new cells generated to replace those lost to the injury are derailed by mutations, Toronto scientists have found.

4 Jan 2021

Study uncovers why cancer patients with liver metastases have poor outcomes

Michael Green, M.D., Ph.D., noticed that when his patients had cancer that spread to the liver, they fared poorly – more so than when cancer spread to other parts of the body. Not only that, but transformative immunotherapy treatments had little impact for these patients.

4 Jan 2021

Researchers develop α-emitting cancer therapy using a novel drug targeting LAT1

A cancer-specific L-type amino acid transporter 1 (LAT1) is highly expressed in cancer tissues.

4 Jan 2021

Biologist receives NIH grant to build software tools to predict cancer drug efficacy

One of the most promising areas of human cancer research is the study of signal transduction, or cell signaling.

4 Jan 2021

P2 COVID-19 study shows no material safety differences between opaganib and control arms

Preliminary data from the non-powered U.S. Phase 2 study of 40 hospitalized patients shows that orally-administered opaganib was safe, with no material safety differences between opaganib and control arms.

4 Jan 2021

New cell therapy can boost immunotherapy against breast cancer

Boosting immune system T cells to effectively attack solid tumors, such as breast cancers, can be done by adding a small molecule to a treatment procedure called chimeric antigen receptor-T (CAR-T) cell therapy, according to a study by researchers at the UNC Lineberger Comprehensive Cancer Center.

4 Jan 2021

Therapy News and Research

UC-MSC infusions reduce risk of death, quicken recovery time in severe COVID-19 cases

Researchers receive $2.1 million NIH grant to study causes of congenital heart defects

Mid-term clinical trial results of two cell therapies for critical limb ischemia show similar outcomes

NCCN publishes new informational resources on health and wellness for cancer survivors

Researchers apply AI to help physicians customize treatments for patients with oral cancers

Non-invasive technique can provide accurate prognosis in unresponsive brain injury patients

Repeated ketamine infusions may be a promising treatment for PTSD patients

Heat treatment during chemotherapy is more effective at destroying cancer cells

Replacing the RNA strand with DNA may enhance efficacy of ASO-based drugs

Study investigates the total non-healthcare cost of chemotherapy

Researchers develop a gene signature for predicting survival in patients with peritoneal carcinomatosis

Experts assess the impact of COVID-19 on pediatric patients with special needs

Inflammation marker linked to increased fatigue in prostate cancer patients treated with ADT

Six clearly distinguishable subtypes of prediabetes identified

Tissue healing after brain injury could spur tumor growth

Study uncovers why cancer patients with liver metastases have poor outcomes

Researchers develop α-emitting cancer therapy using a novel drug targeting LAT1

Biologist receives NIH grant to build software tools to predict cancer drug efficacy

P2 COVID-19 study shows no material safety differences between opaganib and control arms

New cell therapy can boost immunotherapy against breast cancer

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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