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Pembrolizumab shows promising results in patients with classical Hodgkin Lymphoma

Merck, known as MSD outside of Canada and the United States, announced today early study findings demonstrating that patients treated with pembrolizumab, the company's investigational anti-PD-1 cancer therapy, achieved an overall response rate of 66 percent, as assessed by International Harmonization Project response criteria (n=19/29: 95% CI, 46-82).

7 Dec 2014

Emerging strategies to boost healthy RBCs may reduce burden of anemia linked to blood disorders

Emerging treatment approaches may reduce the burden of anemia associated with blood disorders by enhancing production of healthy red blood cells, according to data presented today at the 56th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2014

Katja Heinze, Patrick Choquet receive award for developing intelligent foils for food packaging

The Mainz chemistry professor Katja Heinze and her Luxembourg cooperation partner Dr. Patrick Choquet have received the Interregional Research Award for the development of novel, intelligent foils for food packaging. This is the sixth time this award worth EUR 35,000 has been presented. Its purpose is to promote collaboration in cross-border research projects and reinforce the profile of the interregional research landscape.

7 Dec 2014

New quantum mechanical computational method attains rapid simulation of complex molecular systems

Professor Stephan Irle and Yoshio Nishimoto at the Institute of Transformative Bio-Molecules (ITbM) of Nagoya University and Dr. Dmitri Fedorov of the National Institute of Advanced Industrial Science and Technology (AIST, Tsukuba) have developed a novel ultrafast quantum chemical method enabling rapid simulations of molecules containing more than a million atoms without detrimental loss in accuracy.

7 Dec 2014

OIST Graduate University joins The Brain/MINDS Project in Japan

Governments the world over are now focusing their efforts in research towards mapping the brain to understand its secrets. America has The BRAIN Initiative and Europe, The Human Brain Project. Japan's counterpart is called The Brain/MINDS Project which aims to map the brain at various scales of detail and function over the next ten years. The maps that result from this research would subsequently be used for the development of neurotechnologies and for disease studies. The Okinawa Institute of Science and Technology Graduate University has become one of 17 institutions in Japan to be awarded a grant by the government to conduct this research.

7 Dec 2014

Researchers identify new targets for future CLL therapies

Chronic lymphocytic leukemia (CLL) is among the most frequent leukemias affecting adults in Western countries. It usually occurs in older patients, does not cause any symptoms for a long time and is often only discovered by accident. Despite treatment, relapses frequently occur. The immunologists Dr. Kristina Heinig and Dr. Uta Höpken (Max Delbrück Center for Molecular Medicine, MDC, Berlin-Buch) and the hematologist Dr. Armin Rehm (MDC and Charité - Universitätsmedizin Berlin) have now discovered why this is so.

7 Dec 2014

Study reveals how elite Kenyan athletes succeed in long-distance races

The Journal of Applied Physiology has published an article by Jordan Santos-Concejero of the Faculty of Physical Activity and Sport Sciences of the University of the Basque Country, and entitled `Maintained cerebral oxygenation during maximal self-paced exercise in elite Kenyan runners'. This is a pioneering study in the world of the physiology of exercise, given that it describes for the first time that elite Kenyan athletes have greater brain oxygenation during periods of maximum physical effort, and which contributes to their success in long-distance races.

7 Dec 2014

ASTRO recognized with three 2014 MarCom Awards

The American Society for Radiation Oncology received three 2014 MarCom Awards. MarCom Awards were presented to ASTRO for the Summer 2014 issue of ASTROnews, the RO-ILS: Radiation Oncology Incident Learning SystemTM marketing campaign and the most recent edition of the Radiation Therapy for Prostate Cancer patient brochure.

7 Dec 2014

Study shows link between cardiac abnormalities, sudden unexpected death in epilepsy

Groundbreaking findings describing the link between cardiac abnormalities and sudden unexpected death in epilepsy (SUDEP) will be presented at the American Epilepsy Society's Annual Meeting in December.

7 Dec 2014

New study explores reliability of optogenetics as method of intervention of temporal lobe seizures

Optogenetics is one of the hottest tools in biomedical research today, a method that uses gene therapy to deliver light-sensitive proteins into specific cells. This new tool allows researchers to interact with a single cell or a network of cells with exquisite precision. Whereas imaging and other technologies allow researchers to watch the brain in action, optogenetics enables them to influence those actions.

7 Dec 2014

Scientists devise powerful algorithm to improve effectiveness of research technology harnessing RNAi

Scientists at Cold Spring Harbor Laboratory have devised a powerful algorithm that improves the effectiveness of an important research technology harnessing RNA interference, or RNAi.

7 Dec 2014

BUSM's Carmela Abraham receives 2014 Massachusetts Neuroscience Consortium Award

Carmela Abraham, PhD, professor of biochemistry and pharmacology at Boston University School of Medicine, was one of six recipients of this year's Massachusetts Neuroscience Consortium Award out of nearly 60 applicants. The grant was awarded to her for her work on multiple sclerosis and the role of the life extension protein Klotho in the limited repair of white matter in the disease.

7 Dec 2014

Three-drug combination produces better results in multiple myeloma patients

In the treatment of multiple myeloma, the addition of carfilzomib to a currently accepted two-drug combination produced significantly better results than using the two drugs alone, according to a worldwide research team led by investigators from Mayo Clinic.

7 Dec 2014

Orexo announces positive results from ISTART/006 study

Orexo US, Inc. announced results from the ISTART/006 study, being presented today at the 25th Annual Meeting and Symposium of the American Academy of Addiction Psychiatry in Aventura, Florida, USA.

7 Dec 2014

Drugs we release into the environment significantly affect plant growth, study reveals

The drugs we release into the environment are likely to have a significant impact on plant growth, a new study has revealed.

6 Dec 2014

NIH Collaboratory provides guide to success for pragmatic clinical trials

Pragmatic clinical trials--real-life tests done in real-world settings--are increasingly important for answering pressing questions about how best to deliver health care. But these pragmatic trials require close collaboration between two professional groups who often have contrasting styles. One group is researchers, who follow structure like classical musicians. The other is and health care providers and administrators, who may need to improvise like jazz musicians.

6 Dec 2014

Scientists suspect role of mini-chromosomes in cancers, diseases caused by gene mutations

Cancers are due to genetic aberrations in certain cells that gain the ability to divide indefinitely. This proliferation of sick cells generates tumors, which gradually invade healthy tissue. Therefore, current therapies essentially seek to destroy cancer cells to stop their proliferation. Through high-throughput genetic sequencing of glioblastoma cells, one of the most deadly brain tumors, a team of geneticists from the University of Geneva's (UNIGE) Faculty of Medicine discovered that some of these mutations are caused by supplemental extrachromosomal DNA fragments, called double minutes, which enable cancer cells to better adapt to their environment and therefore better resist to treatments meant to destroy them.

6 Dec 2014

Comb-shaped polymers efficiently protect proteins in vivo

An enzyme that usually triggers strong allergic reactions now circulates in the veins of a group of mice without alerting the immune system. As INRS Énergie Matériaux Télécommunications Research Centre Professor Marc A. Gauthier explains in an article published in the journal Nature Communications, a polymer was used to camouflage the enzyme before it was injected into the rodents. This was achieved by coating the enzyme to avoid an immune response in a manner that does not compromise its activity.

6 Dec 2014

Gap between hospital costs and charges widens significantly, finds new research

The gap between hospital costs and charges has widened significantly. With individuals increasingly responsible for more of their bill and hospitals grappling with payment cuts and payment reforms, charges matter more than ever. New research shows the rise drastically outpaces inflation during the same time and details the rise in cost-to-charge ratio by state.

6 Dec 2014

March of Dimes Celebration of Babies event raises record $1.1 million

March of Dimes, the leading non-profit organization for pregnancy and baby health, raised a record $1.1 million at their 9th annual March of Dimes Celebration of Babies: A Hollywood Luncheon event today at the Beverly Wilshire Hotel in Los Angeles. The 2014 honorees were actor/filmmaker Elizabeth Banks, who was presented with the March of Dimes Grace Kelly Award and Elizabeth Gabler, President, Fox 2000 who was named the March of Dimes Inspiring Woman of the Year.

6 Dec 2014

Research News and Research

Pembrolizumab shows promising results in patients with classical Hodgkin Lymphoma

Emerging strategies to boost healthy RBCs may reduce burden of anemia linked to blood disorders

Katja Heinze, Patrick Choquet receive award for developing intelligent foils for food packaging

New quantum mechanical computational method attains rapid simulation of complex molecular systems

OIST Graduate University joins The Brain/MINDS Project in Japan

Researchers identify new targets for future CLL therapies

Study reveals how elite Kenyan athletes succeed in long-distance races

ASTRO recognized with three 2014 MarCom Awards

Study shows link between cardiac abnormalities, sudden unexpected death in epilepsy

New study explores reliability of optogenetics as method of intervention of temporal lobe seizures

Scientists devise powerful algorithm to improve effectiveness of research technology harnessing RNAi

BUSM's Carmela Abraham receives 2014 Massachusetts Neuroscience Consortium Award

Three-drug combination produces better results in multiple myeloma patients

Orexo announces positive results from ISTART/006 study

Drugs we release into the environment significantly affect plant growth, study reveals

NIH Collaboratory provides guide to success for pragmatic clinical trials

Scientists suspect role of mini-chromosomes in cancers, diseases caused by gene mutations

Comb-shaped polymers efficiently protect proteins in vivo

Gap between hospital costs and charges widens significantly, finds new research

March of Dimes Celebration of Babies event raises record $1.1 million

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