Clinical Trial News and Research

RSS

McMaster vaccine offers new hopes for global fight against TB

A tuberculosis vaccine developed at McMaster University offers new hopes for the global fight against tuberculosis.

3 Oct 2013

Researchers launch phase II clinical trial of rectal microbicide to prevent HIV infections

Taking an important step toward the development of a product to prevent HIV infections associated with unprotected anal sex, researchers today announced the launch of a global Phase II clinical trial of a potential rectal microbicide.

3 Oct 2013

Specialized cells play major role in inflammation that underlies Crohn's disease in small intestine

Scientists have discovered that Crohn's disease, the inflammatory bowel disorder, can originate from specialised intestinal cell type called Paneth cells. As such, they propose that small intestinal Crohn's disease might be a specific disorder of this cell type, providing a possible new target for treatments.

3 Oct 2013

Adamas Pharmaceuticals reports positive results from ADS-5102 Phase 2/3 EASED clinical trial

Adamas Pharmaceuticals, Inc. presented positive results today from the Phase 2/3 EASED clinical trial of ADS-5102 at the World Parkinson's Congress. ADS-5102 is Adamas' proprietary long-acting capsule formulation of amantadine HCl in development for the treatment of levodopa-induced dyskinesia in Parkinson's disease patients.

2 Oct 2013

Hypertension Drug May Aid Cancer Treatment

...

2 Oct 2013

Genetic discovery could take guesswork out of prescribing correct dose of drugs

The discovery of genetic differences affecting up to a third of the population could take the guesswork out of prescribing the correct dose of 25 percent of drugs currently on the market, researchers say.

2 Oct 2013

FDA Approves Takeda-Lundbeck Drug For Major Depressive Disorder

...

1 Oct 2013

Research reveals significant role of Axl receptor in progression, therapeutic resistance of AML

BerGenBio AS, an oncology biopharmaceutical company, announces that a paper entitled "Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine cross-talk of leukemia cells with bone marrow stroma" by Ben-Batalla et al., has been published in Blood, the most cited peer-reviewed research journal in the field of hematology.

1 Oct 2013

OptimEx study may show how to prevent and limit extent of heart failure through exercise

OptimEx, a new 3.5-year study funded by the European Union and coordinated by the Norwegian University of Science and Technology (NTNU), will look at whether exercise could be used both to prevent and treat a specific type of heart failure.

1 Oct 2013

Omeros' OMS824 gets FDA orphan drug designation for treatment of Huntington's disease

Omeros Corporation announced that OMS824, its phosphodiesterase 10 inhibitor, has received orphan drug designation from the U.S. Food and Drug Administration for the treatment of Huntington's disease.

30 Sep 2013

Study suggests relationship between smoking history, response to inhibiting PD-L1/PD-1 pathway

New results from a trial of an antibody that helps the immune system to recognise and attack cancer cells have shown particularly encouraging responses in patients who are smokers or former smokers.

30 Sep 2013

New intravaginal ring delivers drug effectively, guards against HIV for 1 month

It's often said that the HIV/AIDS epidemic has a woman's face. The proportion of women infected with HIV has been on the rise for a decade; in sub-Saharan Africa, women constitute 60 percent of people living with disease. While preventative drugs exist, they have often proven ineffective, especially in light of financial and cultural barriers in developing nations.

28 Sep 2013

SBIR Awards Etubics $1.5M To Manufacture Breast Cancer Immunotherapy

...

27 Sep 2013

HOOKVAC consortium awarded grant to develop, test vaccine for human hookworm

The HOOKVAC consortium, led by the Academic Medical Center at the University of Amsterdam, today announced it has been awarded a grant of six million Euros from the European Commission FP7 programme to expand the Sabin Vaccine Institute Product Development Partnership’s (Sabin PDP) work to develop and test a vaccine for human hookworm, a disease that infects 600-700 million of the world’s poorest people.

27 Sep 2013

HOOKVAC consortium to begin first clinical testing of human hookworm vaccine in West Africa

The HOOKVAC consortium, led by the Academic Medical Center (AMC) at the University of Amsterdam, today announced it has been awarded a grant of six million Euros from the European Commission FP7 programme to expand the Sabin Vaccine Institute Product Development Partnership's (Sabin PDP) work to develop and test a vaccine for human hookworm, a disease that infects 600-700 million of the world's poorest people.

27 Sep 2013

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

A little-used class of antidepressants appears potentially effective in combating a particularly deadly form of lung cancer, according to a new study from researchers at the Stanford University School of Medicine.

27 Sep 2013

Study: Antidepressant drugs prove to be effective against SCLC patients

A bioinformatics approach to repurposing drugs resulted in identification of a class of antidepressants as a potential new treatment for small-cell lung cancer (SCLC), according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

27 Sep 2013

Joslin gets NIH grant to study potential treatment for kidney disease in people with diabetes

The National Institutes of Health awarded Joslin Diabetes Center $24.3 million to fund a clinical trial to study a potential treatment for kidney disease in people with type 1 diabetes.

27 Sep 2013

Center of Reproductive Medicine announces participation in Thrive-IVF Research Study

The Center of Reproductive Medicine today announced its participation in the Thrive-IVF Research Study, a Phase 2 clinical trial sponsored by Nora Therapeutics, Inc., to evaluate the efficacy, safety and tolerability of NT100 in women who have had repeated in vitro fertilization (IVF) failures despite having good quality embryos.

26 Sep 2013

Cerebral imaging in patients with early symptoms of AD may have better clinical outcomes

Patients suffering from early symptoms of Alzheimer's disease who were diagnosed sooner than usual using a brain imaging test received Alzheimer-specific medications earlier than those who did not have the brain imaging results available to their doctors or themselves.

25 Sep 2013

Clinical Trial News and Research

McMaster vaccine offers new hopes for global fight against TB

Researchers launch phase II clinical trial of rectal microbicide to prevent HIV infections

Specialized cells play major role in inflammation that underlies Crohn's disease in small intestine

Adamas Pharmaceuticals reports positive results from ADS-5102 Phase 2/3 EASED clinical trial

Hypertension Drug May Aid Cancer Treatment

Genetic discovery could take guesswork out of prescribing correct dose of drugs

FDA Approves Takeda-Lundbeck Drug For Major Depressive Disorder

Research reveals significant role of Axl receptor in progression, therapeutic resistance of AML

OptimEx study may show how to prevent and limit extent of heart failure through exercise

Omeros' OMS824 gets FDA orphan drug designation for treatment of Huntington's disease

Study suggests relationship between smoking history, response to inhibiting PD-L1/PD-1 pathway

New intravaginal ring delivers drug effectively, guards against HIV for 1 month

SBIR Awards Etubics $1.5M To Manufacture Breast Cancer Immunotherapy

HOOKVAC consortium awarded grant to develop, test vaccine for human hookworm

HOOKVAC consortium to begin first clinical testing of human hookworm vaccine in West Africa

New class of antidepressants appears potentially effective in combating deadly form of lung cancer

Study: Antidepressant drugs prove to be effective against SCLC patients

Joslin gets NIH grant to study potential treatment for kidney disease in people with diabetes

Center of Reproductive Medicine announces participation in Thrive-IVF Research Study

Cerebral imaging in patients with early symptoms of AD may have better clinical outcomes

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery