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Risk-based mammography screening can miss invasive cancers in women in their 40s

A study of breast cancers detected with screening mammography found that strong family history and dense breast tissue were commonly absent in women between the ages of 40 and 49 diagnosed with breast cancer.

2 Dec 2014

Occupational sitting tied to increased likelihood of obesity in women

Occupational sitting is associated with an increased likelihood of obesity, especially among black women, independent of occupational and leisure time physical activity, finds a new study from the School of Medicine and the Brown School at Washington University in St. Louis.

2 Dec 2014

Component of Glycyrrhiza uralensis plant may thwart development of metabolic disorders

New research published in the December 2014 issue of the Journal of Leukocyte Biology, shows that a component found in in the plant, Glycyrrhiza uralensis, may inhibit the development of metabolic disorders by stopping the activation of NLRP3, a protein involved in the disease process.

2 Dec 2014

Scientists challenge prevailing view of how bowel cancer develops in the large intestine

A new study that challenges the prevailing view of how bowel cancer develops in the large intestine is published today in Nature Medicine.

2 Dec 2014

Researchers identify infection control gaps as major culprit in spread of MERS-CoV

Little is known about the often fatal virus known as Middle East respiratory syndrome coronavirus (MERS-CoV), but researchers have identified gaps in infection control as a major culprit in all eleven published cases involving healthcare-associated transmission of the virus.

2 Dec 2014

Sanford-Burnham, Mayo Clinic scientists to jointly find new treatment for resistant hypertension

Sanford-Burnham Medical Research Institute at Lake Nona and Mayo Clinic today announced that a joint team of scientists has been selected as a winner of GlaxoSmithKline's 2014 Discovery Fast Track Challenge.

2 Dec 2014

Digital tomosynthesis improves cancer detection in women with dense breasts

A major new study being presented at the annual meeting of the Radiological Society of North America (RSNA) has found that digital breast tomosynthesis, also known as 3-D mammography, has the potential to significantly increase the cancer detection rate in mammography screening of women with dense breasts.

2 Dec 2014

Greater income inequality associated with more deaths among African Americans

Greater income inequality is linked to more deaths among African Americans, but the effect is reversed among white Americans, who experienced fewer deaths, according to a new study by researchers at the University of California, Berkeley.

2 Dec 2014

Variants of ASIC1a gene appear to be associated with panic disorder

Panic disorder is a severe form of anxiety in which the affected individual feels an abrupt onset of fear, often accompanied by profound physical symptoms of discomfort. Scientists have known from studying twins that genes contribute to the risk of panic disorder, but very little is known about which specific genes are involved.

2 Dec 2014

Researchers warn that Vitamin A deficiency can cause eye problems

Obese patients who have undergone bariatric surgery to shed weight should take the supplements prescribed to them to protect their eyes. Taking in too little Vitamin A, in particular, could in some cases actually cause night blindness, dry eyes, corneal ulcers, and in extreme cases total blindness. This advice comes from Rui Azevedo Guerreiro and Rui Ribeiro of the Centro Hospitalar de Lisboa Central in Portugal, who reviewed what little research there currently is on the occurrence of eye conditions following bariatric surgery.

2 Dec 2014

Alport syndrome: an interview with Dr Paul Grint, CMO, Regulus

Alport Syndrome was first described by a physician called Cecil Alport, back in the late 1920s. It's a genetic disease that affects a certain type of collagen involved in the functioning of the kidney, the ear, and the eye.

1 Dec 2014

Fenofibrate benefits in diabetic retinopathy mediated through PPARα

Peroxisome proliferator–activated receptor α exerts protective effects on retinal pericytes, shows research that explains why fenofibrate is protective against diabetic retinopathy.

1 Dec 2014

Exome sequencing refines 46,XY DSD diagnosis

Exome sequencing can identify a likely genetic cause of 46,XY disorders of sex development in about a third of cases, report researchers.

1 Dec 2014

Closed-loop artificial pancreas system improves diabetes management in adolescents

Research shows that the use of an artificial pancreas system helps to compensate for omission and underestimation of insulin boluses in adolescents with Type 1 diabetes.

1 Dec 2014

Findings could help researchers understand mechanisms involved in ageing

A study from the University of Exeter has found that male flies die earlier than their female counterparts when forced to evolve with the pressures of mate competition and juvenile survival. The results could help researchers understand the mechanisms involved in ageing.

1 Dec 2014

MD Anderson professor receives 13th annual City of Florence Prize in Molecular Sciences

Peter Friedl, M.D., Ph.D., professor of genitourinary medical oncology at The University of Texas MD Anderson Cancer Center, has received one of Italy's top scientific awards for his work in imaging and cancer growth, metastasis and therapy response.

1 Dec 2014

Baxter seeks FDA approval of BAX 855 for treatment of people with hemophilia A

Nektar Therapeutics reported that partner Baxter International Inc. today announced that the company has submitted a biologics license application (BLA) to the United States Food and Drug Administration for the approval of BAX 855, an investigational, extended half-life recombinant factor VIII (rFVIII) treatment for hemophilia A based on ADVATE [Antihemophilic Factor (Recombinant)].

From Baxter International Inc. 1 Dec 2014

Eylea receives Health Canada approval for treatment of CRVO and DME

Bayer Inc. announced today that it has received approval from Health Canada for Eylea (aflibercept, solution for intravitreal injection) for the treatment of diabetic macular edema (DME). This new indication comes just six weeks following the October 16th approval of Eylea for the treatment of visual impairment due to macular edema secondary to central retinal vein occlusion (CRVO).

1 Dec 2014

Arthurian Life Sciences partners with Interrad Medical

Arthurian Life Sciences, the specialist fund management company led by Professor Sir Chris Evans, announced today it has formed a partnership with leading US medtech firm, Interrad Medical Inc.

1 Dec 2014

Predictive model provides information for treating 20% of human diseases

The analysis of drugs, natural products, and chemical substances found in the environment allows the identification of the chemical fragments responsible for a therapeutic or deleterious effect on human health.

1 Dec 2014

Research News and Research

Risk-based mammography screening can miss invasive cancers in women in their 40s

Occupational sitting tied to increased likelihood of obesity in women

Component of Glycyrrhiza uralensis plant may thwart development of metabolic disorders

Scientists challenge prevailing view of how bowel cancer develops in the large intestine

Researchers identify infection control gaps as major culprit in spread of MERS-CoV

Sanford-Burnham, Mayo Clinic scientists to jointly find new treatment for resistant hypertension

Digital tomosynthesis improves cancer detection in women with dense breasts

Greater income inequality associated with more deaths among African Americans

Variants of ASIC1a gene appear to be associated with panic disorder

Researchers warn that Vitamin A deficiency can cause eye problems

Alport syndrome: an interview with Dr Paul Grint, CMO, Regulus

Fenofibrate benefits in diabetic retinopathy mediated through PPARα

Exome sequencing refines 46,XY DSD diagnosis

Closed-loop artificial pancreas system improves diabetes management in adolescents

Findings could help researchers understand mechanisms involved in ageing

MD Anderson professor receives 13th annual City of Florence Prize in Molecular Sciences

Baxter seeks FDA approval of BAX 855 for treatment of people with hemophilia A

Eylea receives Health Canada approval for treatment of CRVO and DME

Arthurian Life Sciences partners with Interrad Medical

Predictive model provides information for treating 20% of human diseases

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