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First detailed look at the molecular pathways underlying sleep apnea

Researchers at the University of Pennsylvania School of Medicine have provided, for the first time, a detailed look at the molecular pathways underlying sleep apnea, which affects more than twelve million Americans, according to the National Institutes of Health.

20 Mar 2008

Disruption of the Contactin 4 gene on chromosome 3 may be linked to autism spectrum disorder

Eli Hatchwell, M.D., Ph.D., Associate Professor of Pathology at Stony Brook University Medical Center, and colleagues have found that a disruption of the Contactin 4 gene on chromosome 3 may be linked to autism spectrum disorder (ASD).

20 Mar 2008

Survival mechanism of T lymphocytes uncovered

When an individual is challenged by a virus, a bacterium or any other infectious agent, several classes of white blood cells are being activated in order to fight the invasion.

19 Mar 2008

Discovery alters long standing concept of fixed protein structure

The thousands of proteins found in nature are simply strings of amino acids, assembled by genes, and scientists have long believed that they automatically fold themselves into uniquely fixed, 3-dimensional shapes to fire the engine of life.

19 Mar 2008

New discovery alters longstanding concept of fixed protein structure

18 Mar 2008

Wine harder on the brain than beer

Scientists say wine damages the brain more than beer or spirits, because it particularly affects the hippocampus, the part of the brain associated with memory and spatial awareness.

17 Mar 2008

Researchers discover signaling system that halts the growth of a childhood brain cancer

A discovery by St. Jude Children's Research Hospital scientists suggests a safer way to treat medulloblastoma, a rare but often fatal childhood brain tumor.

17 Mar 2008

MicroRNAs help zebrafish regenerate fins

Biologists have discovered a molecular circuit breaker that controls a zebrafish's remarkable ability to regrow missing fins, according to a new study from Duke University Medical Center.

17 Mar 2008

Cause of prolonged penile erection

Priapism (prolonged penile erection in the absence of sexual interest) is common in male individuals with sickle cell disease (SCD), a blood disorder characterized by abnormally shaped red blood cells.

14 Mar 2008

Researchers find cause of severe allergic reaction to cetuximab

Clinicians have been perplexed by the fact that some patients given the drug cetuximab - an immune-based therapy commonly used to treat persons diagnosed with head and neck cancer, or colon cancer - have a severe and rapid adverse reaction to the drug.

13 Mar 2008

Thermo Fisher Scientific creates breakthrough gene-silencing tool

Thermo Fisher Scientific Inc. has developed a breakthrough gene-silencing tool that greatly simplifies RNA- interference (RNAi) technology and eliminates barriers associated with previous cellular delivery methods.

From Thermo Fisher Scientific Inc. 12 Mar 2008

Turning off rogue macrophages

University of Pennsylvania scientists studying macrophages, the biological cells that spring from white blood cells to eat and destroy foreign or dying cells, have discovered how these "policemen" differentiate between friend and foe.

12 Mar 2008

Blood test for Parkinson's shows promise

A test that profiles molecular biomarkers in blood could become the first accurate diagnostic test for Parkinson's disease, new research shows.

12 Mar 2008

Low levels of PYY hormone indicate higher risk of developing type 2 diabetes and obesity

It may soon be possible to take a simple blood test and predict whether or not someone has low levels of a particular molecule, predisposing them to the development of Type 2 diabetes.

11 Mar 2008

Japanese find way to make flu vaccine effective for multiple strains

Japanese scientists say they are well on the way to developing influenza vaccines which are effective for multiple strains of the disease, including strains of the bird flu virus.

11 Mar 2008

Pain in fibromyalgia is linked to changes in brain molecule

Researchers at the University of Michigan Health System have found a key linkage between pain and a specific brain molecule, a discovery that lends new insight into fibromyalgia, an often-baffling chronic pain condition.

10 Mar 2008

Paradoxical Alzheimer's finding may provide better understanding of memory loss

Do you remember the seventh song that played on your radio on the way to work yesterday?

10 Mar 2008

Bottom-up fabrication of tiny wires may help detect cancer and other diseases

Bottom-up manufacturing may hold the key to production of tiny medical devices capable of testing for multiple molecules like viruses or cancer markers, according to an interdisciplinary team of Penn State researchers.

10 Mar 2008

Cannabis-derived medicines may help Alzheimer's

Cannabis-derived medicines may one day be used in the treatment of Alzheimer's disease which affects 417,000 people in the UK.

10 Mar 2008

Clearer understanding on how allergy symptoms are triggered

A team of Penn State University researchers is the first to demonstrate that lipid molecules in cell membranes participate in mammals' reactions to allergens in a living cell.

10 Mar 2008