DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Research could change the way people look at gene expression, immune response

Research from the Single-Cell Genomics Centre on the Wellcome Genome Campus could change the way we look at gene expression and immune response. Published in Nature Methods, the new method, TraCeR, provides a powerful tool for research into immune response, vaccination, cancer and autoimmunity.

8 Mar 2016

Specialized tests can help dermatologists provide individualized care for melanoma patients

Melanoma rates in the United States have doubled over the past two decades.1 Fortunately for patients, this increase in melanoma incidence has been accompanied by the development of more effective tools for diagnosis and treatment, including genetic and molecular testing.

7 Mar 2016

Blood test may spot first signs of skin cancer relapse

A BLOOD test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing, according to a study published in the journal Cancer Discovery today (Monday).

7 Mar 2016

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

Researchers observe protection against obesity and insulin resistance but at the cost of prominent fatty liver disease in mice lacking the PEMT enzyme and patients with low levels of PEMT.

7 Mar 2016

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Scientists from the Cancer Therapy & Research Center in San Antonio today (March 4) published work that provides deeper insight into how the Angelina Jolie gene, BRCA1, functions in normal breast tissue and how its loss results in breast cancer.

7 Mar 2016

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

A study of obesity and related metabolic changes on bladder cancer incidence and deaths, and a plan to use stem cells to grow novel urinary tubes are among 10 research projects awarded funding by the Johns Hopkins Greenberg Bladder Cancer Institute.

7 Mar 2016

Athletes carrying specific genotype at greater risk of prolonged recovery following concussion

Genetic research on concussions is progressing in many different avenues. However, researchers presenting their work at the American Orthopaedic Society for Sports Medicine's Specialty Day, believe there may be a new genetic connection regarding recovery rates following a sports-related concussion.

7 Mar 2016

Idelvion approved for use in children and adults with Hemophilia B

The U.S. Food and Drug Administration today approved Idelvion, Coagulation Factor IX (Recombinant), Albumin Fusion Protein, for use in children and adults with Hemophilia B. Idelvion is the first coagulation factor-albumin fusion protein product to be approved, and the second Factor IX fusion protein product approved in the U.S. that is modified to last longer in the blood.

7 Mar 2016

P53 genetic variant heavily implicated in metabolism, new research finds

The study may also provide an evolutionary explanation for differences in populations living farther away from the Equator. Human ancestors may have undergone this change in R72 to promote energy storage in cold climates and during times of famine. However, in modern society, the need for this type of variant in our genes is unnecessary, leading instead to increased risk for obesity and type 2 diabetes. Obesity is also a risk factor for certain types of cancer, so these findings may also explain why the R72 variant of p53 might predispose certain people to cancer.

4 Mar 2016

Study on DNA scrunching may aid in developing new antimicrobial medicines

A research collaboration that combines novel "big-data" informatics tools with expertise in basic biology has uncovered details of an essential process in life: how a crucial enzyme locates the site on DNA where it begins to direct the synthesis of RNA. This finding may aid in the discovery of new antimicrobial medicines, and the powerful technological approaches developed for this research may shed light on other essential cellular processes.

4 Mar 2016

Study highlights new approach to produce coral snake antivenom from synthetically designed DNA

Coral snake venom carries significant neurotoxicity and human injuries can be severe or even lethal. Despite this, antivenom treatments are scarce due to challenges collecting adequate amounts of venom needed to produce anti-elapidic serum. PLOS Neglected Tropical Diseases highlights exciting new research from the Butantan Institute in Brazil using synthetically designed DNA to produce coral-snake antivenom.

4 Mar 2016

IDT continues to support International Genetically Engineered Machine competition

Integrated DNA Technologies (IDT), the global leader in nucleic acid synthesis, announces its 2016 Platinum Level sponsorship of the International Genetically Engineered Machine (iGEM) competition.

4 Mar 2016

Healthy cells actively collaborate with tumours to promote growth of new blood vessels

Healthy cells actively collaborate with tumours by creating a mesh of collagen that encourages cancer cells to build new blood vessels, a new study shows.

4 Mar 2016

Study highlights use of 10x Genomics' GemCode technology platform for genomic analysis

10x Genomics, a company focused on improving and broadening the application of genomic information across healthcare and other industries, today announced the publication of a study that was enabled by the company's GemCode™ technology platform, a powerful new approach that allows researchers to discover previously inaccessible genomic information.

From 10x Genomics, Inc. 4 Mar 2016

Women need antiviral medication Truvada more than men to prevent HIV infection

Women need daily doses of the antiviral medication Truvada to prevent HIV infection while men only need two doses per week due to the way the drug accumulates in different body tissues, according to a new study from pharmacy researchers the University of North Carolina at Chapel Hill.

4 Mar 2016

Researchers reveal link between mitochondrial dysfunction and Fuchs' Endothelial Corneal Dystrophy

Researchers at Schepens Eye Research Institute of Massachusetts Eye and Ear have shown a link between mitochondrial dysfunction in corneal endothelial cells and the development of Fuchs' Endothelial Corneal Dystrophy.

4 Mar 2016

New MyGene2 web tool may help find genes influencing Mendelian disorders

A new web tool, MyGene2, will enable patients and their families to join clinicians and scientists in the search for genes underlying rare disorders. The sharing of health information also will improve knowledge about how gene variants influence symptoms and other clinical features of Mendelian disorders.

3 Mar 2016

Newly developed process improves efficiency of CRISPR gene editing technology

Scientists have developed a process that improves the efficiency of CRISPR, an up-and-coming technology used to edit DNA.

3 Mar 2016

Genetic errors may reduce heart attack risk, study finds

To reduce risk of heart attack, the benefits of a healthy lifestyle are clear. But genetics can still stack the deck. Some people's genes bestow a natural advantage — or disadvantage — in protecting against heart disease, the leading cause of death worldwide.

3 Mar 2016

Scientists solve first 3-D structure of DNAzyme

DNA does not always adopt the form of the double helix which is associated with the genetic code; it can also form intricate folds and act as an enzyme: a deoxyribozyme. A researcher from Spain and other scientists from the Max Planck Institute for Biophysical Chemistry (Germany) have solved the first three-dimensional structure of this biomolecule that has proved much more flexible than previously thought.

3 Mar 2016

DNA News and Research

Further Reading

Research could change the way people look at gene expression, immune response

Specialized tests can help dermatologists provide individualized care for melanoma patients

Blood test may spot first signs of skin cancer relapse

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

Athletes carrying specific genotype at greater risk of prolonged recovery following concussion

Idelvion approved for use in children and adults with Hemophilia B

P53 genetic variant heavily implicated in metabolism, new research finds

Study on DNA scrunching may aid in developing new antimicrobial medicines

Study highlights new approach to produce coral snake antivenom from synthetically designed DNA

IDT continues to support International Genetically Engineered Machine competition

Healthy cells actively collaborate with tumours to promote growth of new blood vessels

Study highlights use of 10x Genomics' GemCode technology platform for genomic analysis

Women need antiviral medication Truvada more than men to prevent HIV infection

Researchers reveal link between mitochondrial dysfunction and Fuchs' Endothelial Corneal Dystrophy

New MyGene2 web tool may help find genes influencing Mendelian disorders

Newly developed process improves efficiency of CRISPR gene editing technology

Genetic errors may reduce heart attack risk, study finds

Scientists solve first 3-D structure of DNAzyme

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo