Antigen News and Research

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Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Novel predictive index for gastric cancer prognosis

A new research paper was published in Oncotarget's Volume 14 on January 31, 2023, entitled, "Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer."

15 Feb 2023

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

In a recent study posted to the bioRxiv* preprint server, researchers identified a novel antiviral pathway different from the interferon (IFN) pathway that inhibited poxvirus(es) replication.

15 Feb 2023

New insights into the role of T-cells during long COVID

Researchers characterize the trajectory of long COVID in patients eight months after recovering from infection.

14 Feb 2023

Enhanced prediction of prostate cancer recurrence using machine learning model

Predicting the course of prostate cancer is challenging because only a fraction of prostate cancer patients experience recurrence after radical prostatectomy or radiation therapy.

14 Feb 2023

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Researchers evaluated the immunogenicity of two vaccine candidates, Pfs25 and PfCSP, based on the mRNA-lipid nanoparticle (LNP) platform.

13 Feb 2023

Declining PSA levels predict improved survival rates in men with non-metastatic castration-resistant prostate cancer

Declines in prostate-specific antigen (PSA) level after treatment with the next-generation androgen receptor inhibitor drug enzalutamide predict improved survival rates in men with non-metastatic castration-resistant prostate cancer (nmCRPC), reports The Journal of Urology, an Official Journal of the American Urological Association.

10 Feb 2023

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

A new review was published in Genes & Cancer on February 1, 2023, entitled, "CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens."

10 Feb 2023

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

10 Feb 2023

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

New adoptive T cell therapies - in which T cells, the immune system's natural hunters patrolling the body for foreign adversaries, are retrieved from cancer-riddled patients, super-charged and amplified outside the body, and then infused back into the same patient - are changing the prospects of cancer patients.

10 Feb 2023

Era of ‘free’ covid vaccines, test kits, and treatments is ending. Who will pay the tab now?

Time is running out for free-to-consumer covid vaccines, at-home test kits, and even some treatments.

10 Feb 2023

Pegylated interferon lambda shows good efficacy against COVID-19

In a recent study published in The New England Journal of Medicine, researchers used the TOGETHER platform trial protocol to perform a phase III randomized controlled trial (RCT) to evaluate the effectiveness of pegylated interferon (IFN) lambda (λ) therapy in outpatients with coronavirus disease 2019 (COVID-19) in Canada and Brazil.

9 Feb 2023

Antigen News and Research

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

Novel predictive index for gastric cancer prognosis

Study finds a new mammalian antiviral response pathway restricting poxviruses replication

New insights into the role of T-cells during long COVID

Enhanced prediction of prostate cancer recurrence using machine learning model

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Declining PSA levels predict improved survival rates in men with non-metastatic castration-resistant prostate cancer

Pathological significance of CEACAMS 1, 5, and 6 in cancer biology, immunology and inflammatory disease

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

Era of ‘free’ covid vaccines, test kits, and treatments is ending. Who will pay the tab now?

Pegylated interferon lambda shows good efficacy against COVID-19

Novel COVID-19 protein component vaccine elicits durable immune response in rodents

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection

Researcher contextualizes a study on IgG4 anti-Spike levels after repeated SARS-CoV-2 mRNA vaccination

Study finds hospitalized obstetric patients with cardiovascular disease and COVID-19 are more symptomatic

A microbiota-driven mechanism underlies severity of leishmaniasis infection

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

New blood test can detect prostate cancer with greater accuracy than current methods

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

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