Biochemistry News and Research

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Transcription factors work together to drive cancer cell proliferation

Scientists have discovered that a well-established cancer cell transcription factor and its newly identified co-factor work together to drive cancer cell proliferation, according to findings published in Science Advances.

16 Mar 2022

Study finds a promising new target for immunity-boosting cancer treatments

Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a study from researchers at Weill Cornell Medicine and Albert Einstein College of Medicine.

16 Mar 2022

Spray-on technology using customized gold nanoparticles could help treat heart disease

Could a spritz of super-tiny particles of gold and peptides on a damaged heart potentially provide minimally invasive, on-the-spot repair?

15 Mar 2022

Study finds elevated inflammation in macrophages months after mild COVID-19

There is a lack of understanding as to why some people suffer from long-lasting symptoms after COVID-19 infection.

15 Mar 2022

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

In a paper published today in Sciences Advances, researchers in the Department of Chemistry and the Department of Physics & Astronomy at the University of California, Irvine revealed new details about a key enzyme that makes DNA sequencing possible.

12 Mar 2022

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

Amyloid beta, a protein known to build up in the brains of people with Alzheimer's disease, also helps skin cancer cells thrive when they spread to the brain, a new study finds.

10 Mar 2022

UH researchers receive grant for developing new imaging technique to peer into ribosomes

Two University of Houston researchers are developing a type of spectroscopy to help understand how ribosomes make proteins deep within cells, the discovery of which could potentially guide drug design to treat cancers and viral infections.

8 Mar 2022

Stress appears to have a negative effect on the learning of movements in mice

Stress seems to have a negative effect on the learning of movements - at least in mice. This is the conclusion of a recent study at the University of Bonn.

8 Mar 2022

Glucocorticoid steroids improve muscle performance through distinct, sex-specific molecular pathways

Glucocorticoid steroids improved muscle performance through distinct, sex-specific molecular mechanisms in mice, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

7 Mar 2022

New, highly promising strategy to overcome a key cause of cancer deaths

A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them.

7 Mar 2022

New technique can upregulate specific genes without permanently altering the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

6 Mar 2022

Cell-hobbling fibrils found across diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

4 Mar 2022

Study may pave the way for better multiple sclerosis drugs

Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments.

4 Mar 2022

COVID-19 and the life sciences; what have we learned and where are we going?

News-Medical attended the 2022 SLAS press briefing where Peter Simpson, Michael Girardi, and Simon Meffan-Main gave their thoughts on the life sciences sector post-COVID-19.

From Society for Laboratory Automation and Screening (SLAS) 4 Mar 2022

Study finds how genetic baggage can accumulate in the genomes of normal and mutant animals

You are probably familiar with the term that some people carry "a lot of extra baggage." Usually that term refers to that person's emotional history, but in genetics and our genomes, "extra baggage" can also describe the transposons lurking in our genomes, a historical record of our genomes surviving traumatic invasions during evolution.

4 Mar 2022

Texas A&M team continues research on the potential cure for Menkes disease

A life-saving cure solution for Menkes Disease, a copper deficiency in young children, is at the center of a licensing agreement by the The Texas A&M University System, through the Intellectual Property and Commercialization office of Texas A&M AgriLife Research, and a California-based biopharmaceutical company, Engrail Therapeutics.

3 Mar 2022

Novel mechanism that connects circadian rhythm and muscle repair discovered

Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury, according to recent findings published in the journal Genes and Development.

28 Feb 2022

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development.

24 Feb 2022

Prenatal phthalate exposure may impact infants' growth and health

Phthalates are endocrine disrupting chemicals that are used in plastics and as food additives. A recent study in Environmental Toxicology and Chemistry examined whether prenatal exposure to phthalates in maternal and cord blood affects birth outcomes in infants.

24 Feb 2022

Researchers unravel essential final steps in the production of mRNA

Proteins need to interact in a complex manner for a so-called "messenger RNA" (mRNA) to be created in human cells from a precursor molecule. mRNA provides a blueprint for proteins; the first vaccines against the coronavirus are also based on mRNAs.

21 Feb 2022

Biochemistry News and Research

Transcription factors work together to drive cancer cell proliferation

Study finds a promising new target for immunity-boosting cancer treatments

Spray-on technology using customized gold nanoparticles could help treat heart disease

Study finds elevated inflammation in macrophages months after mild COVID-19

UCI researchers reveal new details about a key enzyme that makes DNA sequencing possible

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

UH researchers receive grant for developing new imaging technique to peer into ribosomes

Stress appears to have a negative effect on the learning of movements in mice

Glucocorticoid steroids improve muscle performance through distinct, sex-specific molecular pathways

New, highly promising strategy to overcome a key cause of cancer deaths

New technique can upregulate specific genes without permanently altering the genome

Cell-hobbling fibrils found across diverse neurodegenerative diseases

Study may pave the way for better multiple sclerosis drugs

COVID-19 and the life sciences; what have we learned and where are we going?

Study finds how genetic baggage can accumulate in the genomes of normal and mutant animals

Texas A&M team continues research on the potential cure for Menkes disease

Novel mechanism that connects circadian rhythm and muscle repair discovered

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Prenatal phthalate exposure may impact infants' growth and health

Researchers unravel essential final steps in the production of mRNA

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