Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Study describes how human mammary gland becomes highly sensitive to insulin during lactation

Why do so many mothers have difficulty making enough milk to breastfeed? A new study by scientists at Cincinnati Children's Hospital Medical Center and the University of California Davis adds to their previous research implicating insulin's role in lactation success.

6 Jul 2013

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

A second amyloid may play a role in Alzheimer's disease, UC Davis researchers find. A protein secreted with insulin travels through the bloodstream and accumulates in the brains of individuals with type 2 diabetes and dementia, in the same manner as the amyloid beta (Αβ) plaques that are associated with Alzheimer's disease, a study by researchers with the UC Davis Alzheimer's Disease Center has found.

28 Jun 2013

Study finds that triple therapy corrects two core defects in type 2 diabetes

Patients with type 2 diabetes fare significantly better if they are started on three medications at the time of diagnosis than if they are prescribed a single drug and have other therapies added later, a San Antonio researcher said June 22 at the 73rd Scientific Sessions of the American Diabetes Association in Chicago.

25 Jun 2013

Bristol-Myers Squibb and AstraZeneca announce top line results of Phase 4 SAVOR-TIMI-53 clinical trial of Onglyza

Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) today announced top line results of the Phase 4 SAVOR-TIMI-53 (Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus) clinical trial of Onglyza ® (saxagliptin).

20 Jun 2013

Research: Fetal exposure to BPA causes inflammation in fat tissues after birth

New research suggests that fetal exposure to the common environmental chemical bisphenol A, or BPA, causes increased inflammation in fat tissues after birth, which can lead to obesity and metabolic syndrome. Results of the animal study were presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

19 Jun 2013

Special type of IVF may increase risk for insulin resistance among children

A special type of in vitro fertilization, or IVF, may increase the risk for insulin resistance among children conceived in this way, according to a new study from Greece. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Overweight women who skip breakfast experience acute insulin resistance

Overweight women who skip breakfast experience acute, or rapid-onset, insulin resistance, a condition that, when chronic, is a risk factor for diabetes, a new study finds. The results, which were presented Sunday at The Endocrine Society's 95th Annual Meeting in San Francisco, suggest that regularly skipping breakfast over time may lead to chronic insulin resistance and thus could increase an individual's risk for type 2 diabetes.

18 Jun 2013

Depression, antidepressant use may increase risk for diabetes and CVD in postmenopausal women

Postmenopausal women who use antidepressant medication or suffer from depression might be more likely to have a higher body mass index, larger waist circumference and inflammation-all associated with increased risk for diabetes and cardiovascular disease, according to a study led by University of Massachusetts Medical School investigator Yunsheng Ma, PhD, MD, MPH, and published in the June 13 issue of the American Journal of Public Health.

14 Jun 2013

15 minute walk after each meal appears to reduce risk of type 2 diabetes

A fifteen minute walk after each meal appears to help older people regulate blood sugar levels and could reduce their risk of developing type 2 diabetes, according to a new study by researchers at the George Washington University School of Public Health and Health Services (SPHHS).

12 Jun 2013

Sugar ingestion associated with low dopamine release in patients with insulin resistance

Using positron emission tomography (PET) imaging of the brain, researchers have identified a sweet spot that operates in a disorderly way when simple sugars are introduced to people with insulin resistance, a precursor to type 2 diabetes.

11 Jun 2013

Synthetic compound derived from sea anemone toxin shows potential to treat obesity

Scientists at UC Irvine reported this week that a synthetic compound ShK-186, originally derived from a sea anemone toxin, has been found to enhance metabolic activity and shows potential as a treatment for obesity and insulin resistance.

28 May 2013

Obesity directly tied to several cancers

"Obesity is a major risk factor for developing cancer, roughly the equivalent of tobacco use, and both are potentially reversible. Further, obese cancer patients do worse in surgery, with radiation or on chemotherapy - worse by any measure." Karen Basen-Engquist, Ph.D., Director of MD Anderson's new Center for Energy Balance in Cancer Prevention and Survivorship and professor of Behavioral Science.

22 May 2013

Research: Frequency of candy consumption is not associated with adverse health risks

At a time when the spotlight is focused on obesity more than ever, new research suggests that frequency of candy consumption is not associated with weight or certain adverse health risks.

21 May 2013

Study shows treatment of sleep apnea in patients with prediabetes improves blood sugar levels

Optimal treatment of sleep apnea in patients with prediabetes improves blood sugar (glucose) levels and thus can reduce cardiometabolic risk, according to a study to be presented at the ATS 2013 International Conference in Philadelphia.

20 May 2013

Statistics reveal that about 79 million adult Americans walk around with prediabetes

Diabetes is one of the most misunderstood medical conditions. "It's not just about sugar. It's about your heart," says Nancy Ryan, RD, BC-ADM, a registered dietitian, board-certified in advanced diabetes management at Greenwich Hospital in Greenwich, Connecticut.

16 May 2013

Researchers see potential in deploying Akkermansia bacteria to understand and treat obesity

A dominant and useful bacterium called Akkermansia muciniphila is present in the intestinal system of all humans, from babies to the elderly. This microorganism is found in the intestinal mucus layer that protects against intruders.

16 May 2013

Regular marijuana use is associated with favorable indices related to diabetic control, say investigators

Regular marijuana use is associated with favorable indices related to diabetic control, say investigators. They found that current marijuana users had significantly lower fasting insulin and were less likely to be insulin resistant, even after excluding patients with a diagnosis of diabetes mellitus. Their findings are reported in the current issue of The American Journal of Medicine.

15 May 2013

HSPH researchers discover potential target to treat type 2 diabetes and other metabolic diseases

Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in the liver.

8 May 2013

Boehringer Ingelheim Pharmaceuticals, Eli Lilly launch SGLT disease education initiative

Boehringer Ingelheim Pharmaceuticals, Inc. and Eli Lilly and Company today announced the launch of an educational campaign designed to provide healthcare professionals with a greater understanding of the role sodium glucose co-transporters play in maintaining blood sugar balance, or glucose homeostasis.

3 May 2013

Study: Green tea extract with polyethylene glycol could help control body weight gain

Evidence has shown that green tea extract may be an effective herbal remedy useful for weight control and helping to regulate glucose in type 2 diabetes.

30 Apr 2013