Neurodegenerative Diseases News and Research

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Study unravels why women are more susceptible to Alzheimer’s disease

Epidemiological studies have shown that women are twice as likely as men to develop Alzheimer's disease (AD), but the cause of this phenomenon has been unclear.

2 Mar 2022

Nicotinamide riboside supplement shows promise as a potential therapy for Parkinson’s disease

Nicotinamide riboside (NR) is amember of the vitamin B3 family, which can be found in foods like fruits, vegetables, meat, and milk. It is also used as a nutritional supplement to boost cellular levels of NAD (nicotinamide adenine dinucleotide).

2 Mar 2022

Novel drug candidate protects lab mice against cognitive decline by reducing brain inflammation

An anti-inflammatory drug candidate, known as 3,6'-dithiopomalidomide (DP), designed by researchers at the National Institute on Aging, protected lab mice against cognitive decline by reducing brain inflammation.

2 Mar 2022

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

1 Mar 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Mapping cells to understand vascular disease

In this interview, we speak to Dr. Ethan Winkler and Dr. Tomasz Nowakowski about their latest research which illustrated the interplay between vascular and immune cells that contributes to brain hemorrhage.

25 Feb 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Researchers discover how pre-transplant chemotherapy facilitates the replacement of microglial cells

More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases.

21 Feb 2022

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

A 'waste collection' tidies up our cells. If something does not go according to plan, serious diseases such as Alzheimer's or Parkinson's may develop.

20 Feb 2022

New insights into why women develop Alzheimer's symptoms earlier and exhibit faster memory decline

A joint study by Nanyang Technological University, Singapore and National University of Singapore (NUS) scientists has examined why, in mice, female brains are more predisposed to Alzheimer's disease and other neurodegenerative diseases.

16 Feb 2022

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

A new study discusses the state of current knowledge about the potential use of tea polyphenols in the prevention and treatment of COVID-19.

16 Feb 2022

New cell model for Alzheimer's disease could be useful in early diagnosis and testing of new therapies

Researchers at the University of Eastern Finland have developed and characterized a new cell model for Alzheimer's disease that has wide utility for research and could prove useful in early diagnosis and testing of new therapies.

16 Feb 2022

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

Hyperactive microglia can have a protective effect in the course of neurodegenerative diseases

Findings by researchers from Germany support the view that hyperactive immune cells in the brain can have a protective effect in the course of neurodegenerative diseases.

14 Feb 2022

Circadian cycle controls the brain's ability to clear a protein linked to Alzheimer's disease

The brain's ability to clear a protein closely linked to Alzheimer's disease is tied to our circadian cycle, according to research published today in PLOS Genetics.

11 Feb 2022

Scientists discover a new class of potential drug targets for neurodegenerative diseases

Oregon State University scientists have discovered a new class of potential drug targets for people suffering from neurodegenerative conditions such as Alzheimer's, Parkinson's and Lou Gehrig's disease.

10 Feb 2022

Nine new Discovery Grants awarded to fuel the development of ALS treatments

With promising new therapies for amyotrophic lateral sclerosis (ALS) on the horizon, now is the time for ongoing investment in research discovery that will continue to fuel the development of treatments.

10 Feb 2022

Study shows link between loneliness and dementia risk in older adults

As social isolation in the United States has been increasing among older adults, a new study shows a notable link between loneliness and dementia risk, and one that is most striking for Americans who represent a large part of the population.

9 Feb 2022

Gut microbiome modulation induces behavioral, cognitive changes in Alzheimer's disease model

New research in mice for the first time draws a definitive causal connection between changes in the gut microbiome to behavioral and cognitive changes in an animal model of Alzheimer's disease.

8 Feb 2022

Using sugar molecules for in vivo tracking of unlabeled stem cells

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers - made out of sugars - that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Neurodegenerative Diseases News and Research

Study unravels why women are more susceptible to Alzheimer’s disease

Nicotinamide riboside supplement shows promise as a potential therapy for Parkinson’s disease

Novel drug candidate protects lab mice against cognitive decline by reducing brain inflammation

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

Novel molecular pathway shared by two neurodegenerative disorders discovered

Mapping cells to understand vascular disease

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Researchers discover how pre-transplant chemotherapy facilitates the replacement of microglial cells

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

New insights into why women develop Alzheimer's symptoms earlier and exhibit faster memory decline

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

New cell model for Alzheimer's disease could be useful in early diagnosis and testing of new therapies

Researchers create a comprehensive atlas of cerebrovascular cell types

Hyperactive microglia can have a protective effect in the course of neurodegenerative diseases

Circadian cycle controls the brain's ability to clear a protein linked to Alzheimer's disease

Scientists discover a new class of potential drug targets for neurodegenerative diseases

Nine new Discovery Grants awarded to fuel the development of ALS treatments

Study shows link between loneliness and dementia risk in older adults

Gut microbiome modulation induces behavioral, cognitive changes in Alzheimer's disease model

Using sugar molecules for in vivo tracking of unlabeled stem cells

eBook: Using iPSCs models for human disease research and drug discovery eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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