Proliferation News and Research

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The relationship between metabolic disease and alternations in lipid homeostasis

Researchers assessed the function of lipids in metabolic diseases.

4 Jan 2023

Viral short RNAs detected in SARS-CoV-2 RNA transcriptome

Researchers analyzed the ribonucleic acid (RNA) transcriptome associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV-1-infected human cells.

3 Jan 2023

Study reveals novel role of PPARγ acetylation in macrophages in impairing adipose tissue function

As a chronic pro-inflammatory disease, obesity is closely associated with the development of various diseases such as type 2 diabetes, cardiovascular disease and cancers. Obesity is now a major concern for public health.

30 Dec 2022

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues.

28 Dec 2022

How could probiotics be used in the management of gingivitis and periodontitis?

New research explores how probiotic-based therapy in conjunction with established treatment regimens can be an effective approach for combating gingivitis and periodontitis.

28 Dec 2022

Exploring T cell responses during COVID-19 breakthrough infection

Researchers assessed the de novo and recall T cell responses during coronavirus disease 2019 (COVID-19) breakthrough infection.

28 Dec 2022

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Researchers evaluated plasma and nasal antibody titers responses induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccinations among United Kingdom (UK) residents.

23 Dec 2022

Wearable skin patch could help clinicians diagnose tumors, organ malfunction and more

Novel skin patch capable of deep detection of hemoglobin and core temperature.

22 Dec 2022

Sotorasib achieves meaningful anticancer activity in patients with KRAS G12C-mutated metastatic pancreatic cancer

In the Phase I/II CodeBreaK 100 trial, the KRAS G12C inhibitor sotorasib achieved meaningful anticancer activity with an acceptable safety profile in heavily pretreated patients with KRAS G12C-mutated metastatic pancreatic cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

21 Dec 2022

Huge multi-omic data analysis deciphers colorectal cancer genetics

An analysis of more than 100,000 colorectal cancer cases and 154,000 healthy controls published in Nature Genetics uncovered hundreds of signals that may serve as new treatment and prevention targets.

21 Dec 2022

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Researchers examined the pathological impacts of the structural components of SARS-CoV-2 on human periodontal cells and tissue to understand the association between coronavirus disease 2019 (COVID-19) and deteriorating oral health.

20 Dec 2022

The infection potential of influenza A viruses H3 subtype of avian, equine, and swine origin in humans

Researchers determined the zoonotic transmission potential of influenza A viruses (IAVs) H3 subtype of avian, equine, and swine origin.

20 Dec 2022

Researchers identify a small number of 'cheating' cancer cells under hypoxia

Researchers at UConn Health, Yale, and Johns Hopkins have identified that some cancer cells can "cheat" through escaping constraints imposed by lack of oxygen, allowing the cancer cells to continue to grow.

16 Dec 2022

NIH establishes research network to test harm reduction strategies in community settings

To address the overdose crisis in the United States, the National Institutes of Health has established a research network that will test harm reduction strategies in different community settings to inform efforts to help save lives.

16 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Using synthetic gene circuits to better control the timing of immunotherapy

In two separate studies, researchers demonstrate how synthetic biology can be used to tackle a difficult issue in cancer immunotherapy: the way immunotherapy-related approaches focused on short-term killing of tumor cells may fail to eradicate tumors because growth of tumors happens on longer timescales.

16 Dec 2022

Exercise has many benefits even for people with advanced cancer

It is well-known exercise has many benefits, but new Edith Cowan University (ECU) research has revealed just how critically important it can be – even for people with advanced cancer.

15 Dec 2022

Tiny messenger can be promising candidate for treatment of diseases associated with muscular atrophy

WNT messenger proteins are crucial for a variety of cellular functions. A specific WNT messenger can increase muscle mass and improve regeneration in skeletal muscle.

14 Dec 2022

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

Researchers construct a recombinant host-range restricted vaccinia virus Ankara (rMVAs) expressing the spike proteins of several SARS-CoV-2 variants.

11 Dec 2022

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Patients with invasive breast cancer who had low scores on an investigational gene molecular signature had similar rates of local recurrence whether or not they received adjuvant radiation therapy after breast-conserving surgery, according to results of a meta-analysis presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

Proliferation News and Research

The relationship between metabolic disease and alternations in lipid homeostasis

Viral short RNAs detected in SARS-CoV-2 RNA transcriptome

Study reveals novel role of PPARγ acetylation in macrophages in impairing adipose tissue function

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

How could probiotics be used in the management of gingivitis and periodontitis?

Exploring T cell responses during COVID-19 breakthrough infection

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Wearable skin patch could help clinicians diagnose tumors, organ malfunction and more

Sotorasib achieves meaningful anticancer activity in patients with KRAS G12C-mutated metastatic pancreatic cancer

Huge multi-omic data analysis deciphers colorectal cancer genetics

SARS-CoV-2 structural proteins trigger periodontal fibrosis

The infection potential of influenza A viruses H3 subtype of avian, equine, and swine origin in humans

Researchers identify a small number of 'cheating' cancer cells under hypoxia

NIH establishes research network to test harm reduction strategies in community settings

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Using synthetic gene circuits to better control the timing of immunotherapy

Exercise has many benefits even for people with advanced cancer

Tiny messenger can be promising candidate for treatment of diseases associated with muscular atrophy

Intranasal recombinant MVA-based vaccines effective against SARS-CoV-2 variants in mice

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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