Kidney News and Research

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Possibility of a continuously functioning, wearable or implantable artificial kidney

Researchers have developed a human nephron filter (HNF) that would eventually make possible a continuously functioning, wearable or implantable artificial kidney.

30 Aug 2005

Ways to avoid hazards of heart bypass under study

The heart-lung bypass machine that stills the heart while surgeons bypass an adult’s clogged arteries or repair a baby’s malformed heart can also trigger a potentially deadly inflammatory response.

28 Aug 2005

Experimental immunusuppressant drug preserves transplanted kidneys

An international team of transplant physicians has shown that the investigational drug belatacept (LEA29Y) preserves transplanted kidney function as effectively as cyclosporine, the drug most commonly used to prevent the immune system from rejecting transplanted organs.

24 Aug 2005

New drug that selectively blocks immune responses protects kidneys after transplant

In an international clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing acute kidney transplant rejection as cyclosporine, the standard anti-rejection treatment.

24 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005

Reasons for complications with kidney failure patients

Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.

18 Aug 2005

Global prevalence of kidney failure among critically ill patients

A multinational study has found that 5 to 6 percent of patients in intensive care units experience acute kidney failure, and about 60 percent of these patients die in the hospital, according to an article in the August 17 issue of JAMA: The Journal of the American Medical Association.

18 Aug 2005

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

A detectable decline in energy production by mitochondria - the organelles that are the cell's furnace for energy production - seems to be a key problem leading to insulin resistance, and thus to type 2 diabetes, according to studies by Howard Hughes Medical Institute researchers.

16 Aug 2005

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

According to the medical records of 26 children diagnosed with the disease, oral medications reduced levels of a compound in the blood called hemoglobin A1C by an average of 2 percentage points.

15 Aug 2005

DNA chip technology helps with discovery of new type 2 diabetes gene

In a new study appearing in the August 12 issue of the journal Cell, the investigators first identified genes that were altered in their level of expression in islets isolated from people with type 2 diabetes.

13 Aug 2005

Cells direct membrane traffic by channel width

For a glycerol molecule, a measly angstrom's difference in diameter is a road-closed sign: You can't squeeze through unless you are a sleek, water-molecule-sized sports car, say scientists at the University of Illinois at Urbana-Champaign.

11 Aug 2005

New study points to new treatments for some forms of Lou Gehrig's disease

A new study indicates that mutant Cu/Zn superoxide dismutase (SOD1) enzymes that are associated with an inherited form of Lou Gehrig's disease cause the protein to become sticky in tissues. Partial unfolding of the mutant protein can expose hydrophobic residues that may promote abnormal interactions with other proteins or membranes in the cell.

11 Aug 2005

Open nephron-sparing surgery remains the most desirable for the patients

Urologists often view less-invasive surgery techniques as more desirable for the patient, but in a study of open nephron-sparing surgeries (NSS) from 1985 to 2001 at Mayo Clinic, researchers found that the "gold standard" of open surgery for kidney tumors should remain the first choice for many patients. The study appears online today in The Journal of Urology.

10 Aug 2005

Quality of the doctor-patient relationship can greatly affect patients' medication use

Patients who trust their doctors are more likely to stick to their prescription medicines, even if they face high out-of-pocket costs, a new study finds. But patients who have lower levels of trust in their physicians, or who have depression-like symptoms, are much more likely to skip doses or refills when costs become a problem for them.

10 Aug 2005

Placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases as embryonic stem cells

Routinely discarded as medical waste, placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases and regenerate tissues as their more controversial counterparts, embryonic stem cells, suggests a University of Pittsburgh study to be published in the journal Stem Cells and available now as an early online publication in Stem Cells Express.

10 Aug 2005

Obese people are less likely to receive preventive services such as mammograms, Pap smears and flu shots

The Duke study showed that, for a sample of white middle-aged women, as body mass index (BMI) went up, the odds of receiving mammograms and Pap smears went down.

3 Aug 2005

Study finds risk of death increases with peritoneal dialysis over hemodialysis

Researchers at Johns Hopkins have found that in people with end-stage kidney disease (ESRD), choosing peritoneal dialysis over hemodialysis increases their risk of dying by 50 percent.

2 Aug 2005

New research into muscle contraction will give scientists a better understanding of bladder problems and pain during childbirth

Professor Susan Wray, who heads the UK's top rated Department of Physiology, and Dr. Ted Burdyga, are studying muscles in the wall of the ureter, which connects the kidney to the bladder, to understand how muscles respond to signals in the body telling them to contract or relax.

1 Aug 2005

Nationwide survey reports a high rate of concern about body image in both boys and girls

A nationwide survey of more than 10,000 adolescents, published in the August issue of Pediatrics, reports a high rate of concern about body image in both boys and girls, and finds that adolescents with such concerns are much more likely to use hormones and dietary supplements to enhance their physique.

1 Aug 2005

Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

A defect in the mechanics of motors that build tiny cellular hairs is the basis of a serious genetic disorder, according to researchers at UC Davis and Simon Fraser University, Canada.

1 Aug 2005

Kidney News and Research

Possibility of a continuously functioning, wearable or implantable artificial kidney

Ways to avoid hazards of heart bypass under study

Experimental immunusuppressant drug preserves transplanted kidneys

New drug that selectively blocks immune responses protects kidneys after transplant

Protein Sirt1 points to new therapies for type 2 diabetes

Reasons for complications with kidney failure patients

Global prevalence of kidney failure among critically ill patients

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

DNA chip technology helps with discovery of new type 2 diabetes gene

Cells direct membrane traffic by channel width

New study points to new treatments for some forms of Lou Gehrig's disease

Open nephron-sparing surgery remains the most desirable for the patients

Quality of the doctor-patient relationship can greatly affect patients' medication use

Placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases as embryonic stem cells

Obese people are less likely to receive preventive services such as mammograms, Pap smears and flu shots

Study finds risk of death increases with peritoneal dialysis over hemodialysis

New research into muscle contraction will give scientists a better understanding of bladder problems and pain during childbirth

Nationwide survey reports a high rate of concern about body image in both boys and girls

Defect in the mechanics of motors that build tiny cellular hairs is the basis of Bardet-Biedl syndrome

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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