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Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

The link between androgens and COVID-19

A new paper examines the association between androgens and COVID-19, as revealed by the research carried out on this topic throughout the pandemic.

20 May 2022

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Investigators demonstrated S100A9 as an inflammatory biomarker among hospitalized SARS-CoV-2 patients.

20 May 2022

Probiotic supplements accelerate the maturation of microbiome in extremely preterm infants

University of Calgary researchers have shown probiotic supplements can help form a healthy microbiome in the gut of the tiniest infants who are born without a fully formed gut microbiome.

20 May 2022

Existing drug may reduce damage after spinal cord injury, research shows

Scientists from the University of Birmingham have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal cord.

20 May 2022

Scientists explore mortality among women on hormone replacement therapy early in COVID-19 pandemic

A new study assessed the association of hormone replacement therapy or the use of the combined oral contraceptive pill with mortality among women with a previous history of COVID-19.

20 May 2022

The enigma of post-acute infection syndromes

In a recent review published in the journal Nature Medicine, researchers summarized known literature findings of the unexplained post-acute infection syndromes (PAISs).

20 May 2022

Natural immunity weak and short-lived in unvaccinated after Omicron infection

In a recent study posted to the journal Nature, researchers showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infection without SARS-CoV-2 vaccination conferred poor cross-variant neutralizing capacities.

20 May 2022

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

How does the immune system remember and recognize viral invaders it has encountered in the past? A trio of newly published studies of people infected with SARS-CoV-2, vaccinated against the virus or both, are providing tantalizing new clues about the factors that influence the speed and magnitude of the immune system's response to subsequent infection with variants of SARS-CoV-2.

19 May 2022

NIH team documents various types of neuropathy after COVID vaccination

In a recent study posted to the medRxiv* preprint server, researchers investigated if coronavirus disease 2019 (COVID-19) vaccination could result in neuropathic symptoms.

19 May 2022

Plastins may promote disease when they act like workaholics and disrupt cellular environment

A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.

19 May 2022

Kyunurenic acid in cardiovascular therapy

In a recent study posted to the bioRxiv* preprint server, researchers assessed the impact of kynurenic acid on ischemic damage to the heart.

19 May 2022

SARS-CoV-2 zoonotic transmission prediction using ACE2 receptor variation is limited

In a recent study posted to the bioRxiv* preprint server, researchers at the University of Glasgow assessed the variation in angiotensin-converting enzyme 2 (ACE2) in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) host prediction.

19 May 2022

Epistatic drift leads to unpredictability in protein evolution

A critical goal in genetics and evolution is predicting the effects of mutations that may happen in the future and inferring the effects of those that happened in the past.

19 May 2022

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease.

19 May 2022

Male pheromones may be the fountain of youth for aging females' eggs

Male pheromones just might be the fountain of youth for aging female animals' eggs, according to a new Northwestern University study.

19 May 2022

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

New research from Queen Mary University of London, published in Nature Medicine, has shown that molecular profiling of the diseased joint tissue can significantly impact whether specific drug treatments will work to treat rheumatoid arthritis (RA) patients.

19 May 2022

B Cell News and Research

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

The link between androgens and COVID-19

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Probiotic supplements accelerate the maturation of microbiome in extremely preterm infants

Existing drug may reduce damage after spinal cord injury, research shows

Scientists explore mortality among women on hormone replacement therapy early in COVID-19 pandemic

The enigma of post-acute infection syndromes

Natural immunity weak and short-lived in unvaccinated after Omicron infection

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

NIH team documents various types of neuropathy after COVID vaccination

Plastins may promote disease when they act like workaholics and disrupt cellular environment

Kyunurenic acid in cardiovascular therapy

SARS-CoV-2 zoonotic transmission prediction using ACE2 receptor variation is limited

Epistatic drift leads to unpredictability in protein evolution

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

Male pheromones may be the fountain of youth for aging females' eggs

Molecular profiling of diseased joints could transform treatment for rheumatoid arthritis patients

Mice study links dietary cholesterol with exacerbation of influenza

New study reveals the genetic mechanism behind severe staphylococcal infections

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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