Clinical Trial News and Research

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Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

A prominent protein activated by inflammation is the key instigator that converts glioblastoma multiforme cells to their most aggressive, untreatable form and promotes resistance to radiation therapy, an international team lead by researchers at The University of Texas MD Anderson Cancer Center reported online today in the journal Cancer Cell.

30 Aug 2013

Albumin-bound paclitaxel has favorable risk–benefit profile in NSCLC

Albumin-bound paclitaxel plus carboplatin is an effective and well-tolerated first-line treatment in patients with advanced non-small-cell lung cancer, irrespective of histology, study results show.

29 Aug 2013

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

A new clinical study at the University of Michigan Health System will test the ability of a once daily dose of doxycycline to reduce the growth of small abdominal aortic aneurysms.

29 Aug 2013

Future of biomedical innovation depends on new trend for all players to work together for common goal

It's a long, expensive, risky road to turn a scientific breakthrough into a treatment that can help patients. Fewer organizations are trying to tackle the challenges alone, says a new paper from MIT researchers published August 28 in the journal Science Translational Medicine.

29 Aug 2013

Patients attending specialist nurse clinics do not get inferior treatment to that offered by rheumatologists

Patients attending clinical nurse specialist clinics do not get inferior treatment to that offered by consultant rheumatologists, the results of a major new clinical trial have revealed.

29 Aug 2013

TAP block procedure poses no significant risks to patients and cuts postoperative use of narcotics

Surgeons at University Hospitals Case Medical Center, Cleveland, are working to reduce serious complications that have been known to occur with colorectal operations.

29 Aug 2013

Researchers suggest new therapeutic target for brain tumor

Johns Hopkins researchers say they have found a specific protein in nearly 100 percent of high-grade meningiomas — the most common form of brain tumor — suggesting a new target for therapies for a cancer that does not respond to current chemotherapy.

28 Aug 2013

Clinical trial to study benefits of statins in prevention of heart attacks and strokes

Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll Professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University, recently published a commentary in the American Journal of Medicine, about the benefits of statins in the prevention of heart attacks and strokes in subjects previously thought at too low a risk to be treated.

28 Aug 2013

Daily doses of calcium and vitamin supplements may not prevent loss of BMD in women

Women undergoing treatment for breast cancer are widely prescribed calcium and vitamin D supplements to prevent and manage osteoporosis, an unwanted side effect of breast cancer therapies.

28 Aug 2013

Researchers find specific protein in nearly all high-grade meningiomas

Johns Hopkins researchers say they have found a specific protein in nearly 100 percent of high-grade meningiomas -- the most common form of brain tumor -- suggesting a new target for therapies for a cancer that does not respond to current chemotherapy.

28 Aug 2013

Companion diagnostics: an interview with Trevor Hawkins, SVP, Strategy, Innovation and Business Development for Siemens Healthcare Diagnostics

Companion diagnostics is critical in helping to pave the way for personalized medicine, in which the treatment is adapted and precisely tailored to the patient.

From Siemens Healthineers 27 Aug 2013

Northwestern surgical oncologists use minimally invasive procedure to remove malignant melanoma

That's when she received the results from her dermatologist, who removed a part of the blister and had it tested. It turns out that little red bump was malignant melanoma, the leading cause of skin cancer death in the United States. It's a cancer that kills one person every hour, which translates to more than 8,700 Americans each year.

27 Aug 2013

Weight-management intervention effective for weight gain prevention among black women

An intervention not focused on weight loss was effective for weight gain prevention among socioeconomically disadvantaged black women, according to a report published by JAMA Internal Medicine, a JAMA Network publication.

27 Aug 2013

Bioactive compounds in coffee may prevent prostate cancer recurrence, delay progression

Coffee consumption is associated with a lower risk of prostate cancer recurrence and progression, according to a new study by Fred Hutchinson Cancer Research Center scientists that is online ahead of print in Cancer Causes & Control.

27 Aug 2013

Sangamo BioSciences signs definitive agreement to buy Ceregene

Sangamo BioSciences, Inc. announced that it signed a definitive agreement to acquire Ceregene, Inc., a privately held biotechnology company focused on developing adeno-associated virus gene therapies.

26 Aug 2013

Laureate Biopharma collaborates with Dyax to develop new treatment candidate for HAE

Laureate Biopharma is pleased to announce its successful collaboration with Dyax Corp. for process development and cGMP production of a new treatment candidate for hereditary angioedema.

26 Aug 2013

FDA grants marketing approval for VALCHLOR gel for treatment of early stage CTCL

Ceptaris Therapeutics, Inc., a privately held, specialty pharmaceutical company, announced today that the U.S. Food and Drug Administration has granted marketing approval for the orphan drug VALCHLOR (mechlorethamine) gel for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma in patients who have received prior skin-directed therapy.

26 Aug 2013

Immune Pharmaceuticals announces completion of merger with EpiCept Corporation

Immune Pharmaceuticals Inc. announced today the completion of the merger of Immune Pharmaceuticals Ltd. and EpiCept Corporation.

26 Aug 2013

Screening strategy for ovarian cancer appears to be highly specific for detecting disease at early stages

A new screening strategy for ovarian cancer appears to be highly specific for detecting the disease before it becomes lethal. The strategy is described in a study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. If verified in an ongoing clinical trial, it could potentially help save the lives of thousands of women each year in the United States alone.

26 Aug 2013

BESTCILIA project aims to improve screening, treatment of Primary Ciliary Dyskinesia

Primary Ciliary Dyskinesia is mainly a lung disease: a rare, genetically heterogeneous disorder resulting from dysfunction of small hair-like organelles (cilia) that clean the upper and lower airways. It can also affect multiple organs beside the respiratory system, and may cause serious impairment and lower quality of life. Its prevalence is estimated to be about 1 in 16,000.

26 Aug 2013

Clinical Trial News and Research

Protein activated by inflammation converts glioblastoma multiforme cells to most aggressive form

Albumin-bound paclitaxel has favorable risk–benefit profile in NSCLC

Study to test ability of doxycycline dose to reduce growth of abdominal aortic aneurysms

Future of biomedical innovation depends on new trend for all players to work together for common goal

Patients attending specialist nurse clinics do not get inferior treatment to that offered by rheumatologists

TAP block procedure poses no significant risks to patients and cuts postoperative use of narcotics

Researchers suggest new therapeutic target for brain tumor

Clinical trial to study benefits of statins in prevention of heart attacks and strokes

Daily doses of calcium and vitamin supplements may not prevent loss of BMD in women

Researchers find specific protein in nearly all high-grade meningiomas

Companion diagnostics: an interview with Trevor Hawkins, SVP, Strategy, Innovation and Business Development for Siemens Healthcare Diagnostics

Northwestern surgical oncologists use minimally invasive procedure to remove malignant melanoma

Weight-management intervention effective for weight gain prevention among black women

Bioactive compounds in coffee may prevent prostate cancer recurrence, delay progression

Sangamo BioSciences signs definitive agreement to buy Ceregene

Laureate Biopharma collaborates with Dyax to develop new treatment candidate for HAE

FDA grants marketing approval for VALCHLOR gel for treatment of early stage CTCL

Immune Pharmaceuticals announces completion of merger with EpiCept Corporation

Screening strategy for ovarian cancer appears to be highly specific for detecting disease at early stages

BESTCILIA project aims to improve screening, treatment of Primary Ciliary Dyskinesia

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