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Scientists discover new way to predict healthy individuals at risk of developing AML

An international team of leukemia scientists has discovered how to predict healthy individuals at risk of developing acute myeloid leukemia, an aggressive and often deadly blood cancer.

10 Jul 2018

Researchers develop new method to identify genes contributing to heritable cancer risk

Researchers at the Centre for Genomic Regulation in Barcelona developed a new method to systematically identify genes contributing to heritable cancer risk.

10 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Study: Mitochondrial DNA in nanovesicles is the alarm that activates antiviral genetic program

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have provided valuable information about the defense mechanisms of the immune system during the early stages of the response to pathogens such as viruses and bacteria.

10 Jul 2018

New approach could greatly enhance people's long-term tolerance for transplants

Currently, people receiving organ transplants must take drugs to suppress the inflammatory immune response that leads to rejection. Even so, almost all recipients eventually lose their transplant.

10 Jul 2018

Fluorescent zebrafish genes provide clues about neuroblastoma

Researchers have created transgenic zebrafish that could help them understand how neuroblastoma, a common pediatric cancer, develops.

10 Jul 2018

Fluorescent fish could help find origins of neuroblastoma

A new type of zebrafish that produces fluorescent tags in migratory embryonic nerve precursor cells could help a Rice University neurobiologist and cancer researcher find the origins of the third-most common pediatric cancer in the U.S.

10 Jul 2018

Researchers identify genes associated with aggressive behavior

Researchers from the University of Barcelona and collaborators have pin-pointed forty genes that are associated with aggressive behaviors in humans and in mice.

9 Jul 2018

Study finds key evidence about genetic make-up of heart condition linked to sudden arrhythmic death

A new study published in Circulation, a peer-reviewed journal of the American Heart Association and led by a cardiologist at the Peter Munk Cardiac Centre at Toronto General Hospital has found evidence that only one of the 21 genes normally associated with Brugada Syndrome, a serious genetic heart condition associated with the risk of sudden arrhythmic death, is a definitive cause of the condition.

9 Jul 2018

Protein complex that helps shape destiny of developing T cells identified

Like a mentor helping medical students choose between specialties, a protein complex helps shape the destiny of developing T cells, St. Jude Children's Research Hospital scientists have reported.

9 Jul 2018

Researchers discover biomarkers that accurately identify hypervirulent K. pneumoniae

Imagine a pathogen that infects completely healthy people and can cause blindness in one day and flesh-eating infections, brain abscesses and death in just a few days.

9 Jul 2018

Widespread transfer of genes between species appears to be key driver of evolution

Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between species has radically changed the genomes of today's mammals, and been an important driver of evolution.

9 Jul 2018

Scientists create predictive model for neuroblastoma that incorporates early developmental signals

Neuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins.

9 Jul 2018

Researchers discover critical link in mapping recurrent mutations of melanoma

A critical link in mapping recurrent mutations of melanoma -- the most serious form of skin cancer in humans -- has been discovered by researchers at Washington State University School of Molecular Biosciences, in collaboration with researchers at Georgia State University.

6 Jul 2018

Single-cell RNA sequencing reveals how complex brain circuit works

The complexity of the human brain presents scientists with immense challenges as they try to find new treatments for a host of diseases and conditions. But the advent of a new technology known as single-cell RNA sequencing is opening a window into how the brain works.

6 Jul 2018

Nanofiber-based wound dressings loaded with vitamin D spur production of antimicrobial peptide

Nanofiber-based wound dressings loaded with vitamin D spur the production of an antimicrobial peptide, a key step forward in the battle against surgical site infections, or SSIs.

6 Jul 2018

Researchers find new way to convert skin cells into pluripotent stem cells

Our bodies consist of many different kinds of cells, each with their own role. The Japanese scientist Shinya Yamanaka had made earlier the discovery, earning the Nobel Prize in 2012, that cells from adult skin can be converted to cells typical of early embryos, so-called induced pluripotent stem cells.

6 Jul 2018