Clinical Trial News and Research

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Clinical trial of Echo Therapeutics' Symphony CGM System receives IRB approval

Echo Therapeutics, Inc., a company developing its needle-free Symphony CGM System as a non-invasive, wireless, transdermal continuous glucose monitoring system, announced today that the Company's clinical trial of its Symphony CGM System has received Institutional Review Board approval.

21 May 2013

TB clinical drug trials in jeopardy due to federal sequestration funding cuts

Innovative and potentially game-changing clinical trials to develop new drug regimens to prevent and treat tuberculosis, the second leading global infectious disease killer, are in jeopardy due to federal "sequestration" funding cuts.

21 May 2013

New research suggests that listening to music lowers anxiety, sedation in ventilated patients

New research suggests that for some hospitalized ICU patients on mechanical ventilators, using headphones to listen to their favorite types of music could lower anxiety and reduce their need for sedative medications.

21 May 2013

Study suggests that fluid, sodium restrictions have no effect on weight loss in ADHF patients

A clinical trial of 75 patients hospitalized with acute decompensated heart failure suggests that aggressive fluid and sodium restriction has no effect on weight loss or clinical stability at three days but was associated with an increase in perceived thirst, according to a study published Online First by JAMA Internal Medicine, a JAMA Network publication.

21 May 2013

XenoPort's Arbaclofen placarbil fails to meet co-primary endpoints in Phase 3 clinical trial

XenoPort, Inc. announced today top-line results from its pivotal Phase 3 clinical trial of arbaclofen placarbil for the treatment of patients with spasticity due to multiple sclerosis.

20 May 2013

Cell Therapeutics announces issuance of final benefit assessment report for PIXUVRI

Cell Therapeutics, Inc. today reported that Germany's Federal Joint Committee has issued its final benefit assessment report for PIXUVRI (pixantrone), which is indicated as a monotherapy for the treatment of adult patients with aggressive B-cell non-Hodgkin lymphoma (NHL) who have failed two or three prior lines of therapy.

20 May 2013

Joint replacement surgery might be avoidable in the future, suggest scientists

Scientists at Johns Hopkins have turned their view of osteoarthritis inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, they now have evidence that the bone underneath the cartilage is also a key player and exacerbates the damage.

20 May 2013

Patients with treatment-resistant depression benefit from ketamine

Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to-date led by researchers from the Icahn School of Medicine at Mount Sinai.

20 May 2013

EndoChoice's new Fuse system improves accuracy of colonoscopy procedure

Although colonoscopy exams prevent many colon cancer deaths and are considered the most sensitive method for detecting colorectal cancers, the procedure is not completely effective in preventing cancer cases. EndoChoice Inc. today unveiled research that shows that its new Fuse system significantly improves the accuracy of this procedure and greatly reduces the number of adenomas missed by colonoscopists.

20 May 2013

Safety and efficacy evaluation methods for medical devices

Medical devices are any medical items that are neither a drug nor a biological product. In light of their different mechanisms, actions and regulatory requirements, medical device trail evaluations are much more complicated than drug trails due to their unique clinical practices.

18 May 2013

A*STAR, Cytos Biotechnology provide update on Phase 1 clinical trial of H1N1 influenza vaccine

Singapore's Agency for Science, Technology and Research and Switzerland's Cytos Biotechnology AG today announced that the first healthy volunteer has been dosed in a Phase 1 clinical trial with their H1N1 influenza vaccine candidate based on Cytos' proprietary bacteriophage Qbeta virus-like particle technology.

17 May 2013

Cedars-Sinai launches new clinical trial to study effects of cabozantinib in prostate cancer patients

Researchers at Cedars-Sinai have launched a new clinical trial to investigate the effects of a cancer-fighting drug therapy that has shown favorable outcomes in patients with advanced metastatic prostate cancer.

17 May 2013

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

Northwest Biotherapeutics, a biotechnology company developing DCVax-L personalized immune therapies for solid tumor cancers, today announced that its Phase III clinical trial with DCVax-L for brain cancer has been initiated at King's College Hospital in the UK.

17 May 2013

InVivo Therapeutics to sponsor Working 2 Walk symposium

InVivo Therapeutics Holdings Corp., a developer of groundbreaking technologies for the treatment of spinal cord injuries and other neurotrauma conditions, today announced that the Company is the Title Sponsor of the 8th annual Working 2 Walk Science & Advocacy Symposium taking place September 27-28, 2013 at the Boston Convention & Exhibit Center in Boston, MA.

16 May 2013

Idelalisib phase 1 clinical trial shows positive results in patients with CLL

A new oral targeted drug, idelalisib (GS-1101), has the potential to stave off the need for additional treatments for relapsed or treatment-resistant chronic lymphocytic leukemia, according to a study led in part by Dana-Farber Cancer Institute investigators.

16 May 2013

Study underscores new paradigm in cancer therapy

In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers.

16 May 2013

Prostate cancer drug Xofigo gets FDA approval

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs.

16 May 2013

Tokai Pharmaceuticals raises $35.5M in Series E financing

Tokai Pharmaceuticals, Inc., a biopharmaceutical company focused on developing new treatments for prostate cancer, today announced that the company raised $35.5 million in a Series E financing based on encouraging clinical progress and investor support for galeterone (TOK-001), Tokai's lead prostate cancer drug candidate.

15 May 2013

UIC's Center for Clinical and Translational Science selects six research projects for new pilot grants

The University of Illinois at Chicago's Center for Clinical and Translational Science has selected six research projects to receive pilot grants in 2013.

15 May 2013

Renaissance in drug development for rare diseases

Once famously described as "orphan diseases, too small to be noticed, too small to be funded" in the Hollywood drama Lorenzo's Oil, rare diseases are getting unprecedented attention today among drug manufacturers, who are ramping up research efforts and marketing new medicines that promise fuller lives for children and other patients with these heartbreaking conditions.

14 May 2013

Clinical Trial News and Research

Clinical trial of Echo Therapeutics' Symphony CGM System receives IRB approval

TB clinical drug trials in jeopardy due to federal sequestration funding cuts

New research suggests that listening to music lowers anxiety, sedation in ventilated patients

Study suggests that fluid, sodium restrictions have no effect on weight loss in ADHF patients

XenoPort's Arbaclofen placarbil fails to meet co-primary endpoints in Phase 3 clinical trial

Cell Therapeutics announces issuance of final benefit assessment report for PIXUVRI

Joint replacement surgery might be avoidable in the future, suggest scientists

Patients with treatment-resistant depression benefit from ketamine

EndoChoice's new Fuse system improves accuracy of colonoscopy procedure

Safety and efficacy evaluation methods for medical devices

A*STAR, Cytos Biotechnology provide update on Phase 1 clinical trial of H1N1 influenza vaccine

Cedars-Sinai launches new clinical trial to study effects of cabozantinib in prostate cancer patients

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

InVivo Therapeutics to sponsor Working 2 Walk symposium

Idelalisib phase 1 clinical trial shows positive results in patients with CLL

Study underscores new paradigm in cancer therapy

Prostate cancer drug Xofigo gets FDA approval

Tokai Pharmaceuticals raises $35.5M in Series E financing

UIC's Center for Clinical and Translational Science selects six research projects for new pilot grants

Renaissance in drug development for rare diseases

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