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Common heart drugs are safe for patients hospitalized with COVID-19

Heart patients hospitalized with COVID-19 can safely continue taking angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs), according to the BRACE CORONA trial presented in a Hot Line session today at ESC Congress 2020.

1 Sep 2020

Cannabis-impaired driving among topics to be addressed at forensic toxicology nonprofit’s first virtual event

The Society of Forensic Toxicologists will host SOFTember, its virtual event in lieu of its annual meeting, which would have celebrated its 50th anniversary.

1 Sep 2020

Newly approved drugs in Canada lack key pediatric drug information

Newly approved drugs in Canada lack important pediatric drug information in their product monograph, according to an analysis led by McMaster University and McMaster Children's Hospital.

1 Sep 2020

14 existing drugs identified as SARS-CoV-2 main protease inhibitors

Now, a new study published on the preprint server bioRxiv in August 2020 reports on the identification of 14 compounds that can inhibit the key viral enzyme called the Main Protease (MPro) at micromolar concentrations.

1 Sep 2020

Researchers propose new reforms to improve transparency of drug authorizations

On March 28, the Food and Drug Administration (FDA) exercised its Emergency Use Authorization (EUA) authority to allow the use of hydroxychloroquine for the treatment of COVID-19. On June 15, after a number of studies failed to find positive effects, the agency revoked this authorization.

1 Sep 2020

New study weighs effectiveness of three anticonvulsant drugs to treat deadly seizures

Three anticonvulsant drugs commonly used to stop prolonged, potentially deadly seizures each work equally well, according to a national study led by physicians at UT Southwestern.

31 Aug 2020

Researchers launch study to evaluate safety of HIV prevention methods in breastfeeding women

The development of safe and effective HIV prevention methods for cisgender women has long been a global health priority, yet research in women during pregnancy and breastfeeding, when they are most vulnerable to infection, has lagged years behind.

31 Aug 2020

New microgel drug delivery method could improve effectiveness of pancreatic islet transplants

Pancreatic islet transplants, which revive insulin production to treat type 1 diabetes, only last an average of three years.

31 Aug 2020

COVID-19 patients may experience long-term cardiovascular complications

Researchers at the University of Washington in Seattle have conducted a study suggesting that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can directly infect heart tissue and contribute to whole-organ cardiac dysfunction.

31 Aug 2020

FDA approves a hybrid closed loop diabetes management device for young pediatric patients

Today, the U.S. Food and Drug Administration approved the MiniMed 770G System, a hybrid closed loop diabetes management device that is intended to automatically monitor glucose (sugar) and provide appropriate basal insulin doses with little or no input from the users or their caregivers for use by individuals aged 2 to 6 with type 1 diabetes.

31 Aug 2020

Antihypertensive drugs are not linked to cancer, shows study

There is no evidence that blood pressure lowering drugs increase the risk of cancer, according to the most extensive study conducted on the topic. The late breaking research is presented today at ESC Congress 2020.

31 Aug 2020

Patients with newly diagnosed atrial fibrillation benefit from early rhythm control therapy

Patients with newly diagnosed atrial fibrillation benefit from early rhythm control therapy, according to results of the EAST-AFNET 4 trial presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

Trimetazidine does not improve outcomes in patients with chronic or acute coronary syndromes

Trimetazidine administered after successful percutaneous coronary intervention (PCI) does not improve outcomes in patients with chronic or acute coronary syndromes, according to results of the ATPCI trial presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Now, a team of researchers at the University of Alberta in Canada has identified viral inhibitors that they claim are potential candidates as a treatment for COVID-19. The team is set to launch clinical trials of the drug that is used as a treatment for a type of coronavirus in cats.

31 Aug 2020

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

In a fascinating new preprint paper published on bioRxiv* in August 2020, the researchers report “the synthesis and antiviral evaluation of three novel lipophilic prodrugs of RVn-monophosphate that are substantially more active than Remdesivir in cells infected with SARS-CoV-2.” These could be of immense use in treating COVID-19 patients early and helping to end transmission.

30 Aug 2020

FDA announces public meeting to discuss development and licensure of COVID-19 vaccines

The U.S. Food and Drug Administration announced that a public meeting of the Vaccines and Related Biological Products Advisory Committee will be held on CutOct. 22, 2020, to discuss the general matter of the development, authorization, and/or licensure of vaccines indicated to prevent COVID-19.

29 Aug 2020

Drugs News and Research

Common heart drugs are safe for patients hospitalized with COVID-19

Cannabis-impaired driving among topics to be addressed at forensic toxicology nonprofit’s first virtual event

Newly approved drugs in Canada lack key pediatric drug information

14 existing drugs identified as SARS-CoV-2 main protease inhibitors

Researchers propose new reforms to improve transparency of drug authorizations

New study weighs effectiveness of three anticonvulsant drugs to treat deadly seizures

Researchers launch study to evaluate safety of HIV prevention methods in breastfeeding women

New microgel drug delivery method could improve effectiveness of pancreatic islet transplants

COVID-19 patients may experience long-term cardiovascular complications

FDA approves a hybrid closed loop diabetes management device for young pediatric patients

Antihypertensive drugs are not linked to cancer, shows study

Patients with newly diagnosed atrial fibrillation benefit from early rhythm control therapy

Trimetazidine does not improve outcomes in patients with chronic or acute coronary syndromes

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

FDA announces public meeting to discuss development and licensure of COVID-19 vaccines

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Clinicians may have to look beyond opioids to tackle nation’s substance use epidemic

Bulky benchtops for fingerprinting drugs could be replaced with a tiny photonic chip

International researchers study the effects of pathogenic fungus Candida auris

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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