Molecule News and Research

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Secrets of protein folding revealed

A team led by biophysicist Jeremy Smith of the University of Tennessee and Oak Ridge National Laboratory (ORNL) has taken a significant step toward unraveling the mystery of how proteins fold into unique, three-dimensional shapes.

18 Sep 2007

Scientists learn three-dimensional structure of enzyme in unusual virus

Biologists have determined the three-dimensional structure of an unusual viral enzyme that is required in the assembly of new viruses.

18 Sep 2007

Nanoparticle that delivers vaccines more effectively

Good news for public health: Bioengineering researchers from the EPFL in Lausanne, Switzerland, have developed and patented a nanoparticle that can deliver vaccines more effectively, with fewer side effects, and at a fraction of the cost of current vaccine technologies.

18 Sep 2007

Mechanism for the in-vivo transport of siRNA

It all started with flowers: in the nineties of the last century Norwegian researchers discovered that additional copies of a particular gene in petunias inhibited its activity instead of reinforcing it as had been assumed.

18 Sep 2007

Circulating fats kill transplanted pancreas cells

New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease.

18 Sep 2007

Solid state NMR spectroscopy reveals the workings of 'Mother Nature's Blowtorch'

Using atom-level imaging techniques, University of Michigan researchers have revealed important structural details of an enzyme system known as "Mother Nature's blowtorch" for its role in helping the body efficiently break down many drugs and toxins.

17 Sep 2007

DNA as a picoforce standard

DNA, the biomolecule that provides the blueprint for life, has a lesser-known identity as a stretchy polymer.

17 Sep 2007

Byproduct of cholesterol metabolism blocks heart health benefits of estrogen

17 Sep 2007

N-cofilin molecule protects from neuronal disorders

Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly – a form of mental retardation - result from abnormal migration of nerve cells during the development of the brain.

17 Sep 2007

Byproduct of cholesterol interferes with the beneficial effects of estrogen on the heart

A new study possibly offers a biological reason why hormone replacement therapy (HRT) fails to protect some postmenopausal women from heart disease.

17 Sep 2007

New green methods for coating drugs in plastics

Green chemistry is being employed to develop revolutionary drug delivery methods that are more effective and less toxic - and could benefit millions of patients.

13 Sep 2007

New technique detects how proteins undergo changes inside a cell

In the September issue of Molecular & Cellular Proteomics , scientists describe a new technique that can detect how proteins undergo changes inside a cell.

13 Sep 2007

New insight into breast cancer development in high-risk women

Physicians who treat women with the breast cancer susceptibility gene BRCA1 often remove their patients' ovaries to eliminate the source of estrogen they believe fuels cancer growth.

12 Sep 2007

New instrumentation to help fight obesity and diabetes

World-first equipment, made exclusively for UQ scientists, will determine how to produce food which is better for us, but still tastes good.

12 Sep 2007

Potential new drug target for preventing postmenopausal bone loss

Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone.

11 Sep 2007

Scientists identify process that causes blood vessels to constrict during and after a heart attack

They've also demonstrated that delivering a vital molecule that is depleted during this process directly to those blood vessels can reverse damage and help restore blood flow.

11 Sep 2007

Novel enzyme may offer huge range of potential therapeutic agents

By guiding an enzyme down a new evolutionary pathway, a team of University of Wisconsin-Madison researchers has created a new form of an enzyme capable of producing a range of potential new therapeutic agents with anticancer and antibiotic properties.

10 Sep 2007