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HSG conducts clinical trial with novel drug formulation for treating Huntington disease

The Huntington Study Group (HSG), under the leadership of Samuel Frank, MD, Principal Investigator, (Boston University School of Medicine) and Claudia Testa, MD, PhD, co-Principal Investigator (Virginia Commonwealth University), is conducting a clinical trial with a formulation of the novel drug SD-809 in the treatment of HD the United States and Canada.

24 Jun 2013

Comprehend Systems collaborates with Merge eClinical to expands its clinical research space

Driven by increasing demand for its cloud-based data insights solution, Comprehend Systems further expands its reach in the clinical research space with a partnership with Merge Healthcare's eClinical Solutions division.

21 Jun 2013

New $11 million grant for lowering stroke risk among black and young populations

A new $11 million grant to Kaiser Permanente Northern California and UC San Francisco will support a multifaceted research program aimed at lowering stroke risk among black populations and younger stroke victims by targeting high blood pressure, also known as hypertension.

21 Jun 2013

New treatment option for patients with aortic stenosis

Robert Stoler, MD, FACC, FSCAI, director of the Cardiac Catheterization Lab at Baylor Heart and Vascular Hospital and co-medical director, Division of Cardiology, is leading Baylor's participation in an exciting clinical trial to research a new treatment option for AS patients.

From Medtronic 21 Jun 2013

Laughing gas is associated with increased risk for perioperative cardiac events

A clinical trial published in the July issue of Anesthesiology may shed some light on whether nitrous oxide ("laughing gas") causes an increased risk for cardiac events, including heart attacks after surgery, particularly among high-risk patients.

20 Jun 2013

Medicago produces Rotavirus VLP vaccine candidate using plant-based manufacturing platform

Medicago Inc. (TSX: MDG; OTCQX: MDCGF), a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced the successful production of a Rotavirus VLP vaccine candidate comprising all four structural antigens of rotavirus (VP2, VP4, VP6 and VP7) using Medicago's plant-based manufacturing platform.

20 Jun 2013

BerGenBio AS starts Phase 1 Clinical Trial for BGB324 oral AXL inhibitor

BerGenBio AS today announced the start of a Phase 1 Clinical Trial for BGB324, a first-in-class small molecule inhibitor of AXL tyrosine kinase. BGB324 is a highly selective, oral AXL inhibitor that blocks the epithelial-mesenchymal transition (EMT), which is a key driver of metastasis (cancer spread) and drug-resistance. The Phase 1 clinical trial of BGB324 is a single ascending dose study designed to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of BGB324.

20 Jun 2013

Banyan Biomarkers completes $6 million series A funding for further biomarker research

Banyan Biomarkers, Inc. today announced that it has completed a $6 million series A funding from private investors for further biomarker research and continued development of a traumatic brain injury (TBI) diagnostic test. Currently, the company is enrolling subjects in a 2,000 patient pivotal clinical trial funded by a $26.3 million contract with the United States Department of Defense.

20 Jun 2013

Researchers launch clinical trial on stem cells to prevent amputations in end stage PAD

University Hospitals Case Medical Center clinical researchers have launched an innovative clinical trial, unique in its design, which will evaluate the ability of a patient's own stem cells to prevent leg amputations in end stage peripheral arterial disease (PAD).

20 Jun 2013

Bristol-Myers Squibb and AstraZeneca announce top line results of Phase 4 SAVOR-TIMI-53 clinical trial of Onglyza

Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) today announced top line results of the Phase 4 SAVOR-TIMI-53 (Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus) clinical trial of Onglyza ® (saxagliptin).

20 Jun 2013

Pharma IQ releases new infographic summary of results from industry survey

Pharma IQ is pleased to announce the release of a brand new infographic summary of the results from an industry survey conducted earlier this year.

From IQPC Ltd 19 Jun 2013

Ico Therapeutics completes Phase 2 iDEAL study for treatment of diabetic macular edema

iCo Therapeutics Inc. announced today that it has completed enrollment of its Phase 2 iDEAL study evaluating the efficacy and safety after repeated injections of iCo-007 in patients with Diabetic Macular Edema (DME). The study has shown a good safety profile with no drug-related serious adverse events to date.

19 Jun 2013

New framework to improve safety and effectiveness of surgical procedures, implantable devices

An international team of investigators co-led by Weill Cornell Medical College is offering a new framework for evidence-based surgery and device research, similar to the kind of risk and benefit analysis used in evidence-based medicine.

19 Jun 2013

Patient enrollment and trial duration heavily impact the total cost of Phase 1 oncology trial

Both the number of patients and trial duration heavily impact a Phase 1 oncology trial's total cost. The underlying force driving most costs is patient enrollment. As the time to reach full enrollment increases, the trial lasts longer and the cost of maintaining and staffing clinical sites rises.

19 Jun 2013

Signaling pathway correlates with EGFR status and poor survival in breast cancer patients

Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point.

19 Jun 2013

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

An analysis by the Evidence-based Practice Center at Oregon Health & Science University has found that previously published clinical trial studies about a controversial bone growth product used in spinal surgeries overstated the product's effectiveness.

19 Jun 2013

UHCMC physicians design new procedure to clear blocked carotid arteries, prevent stroke

Physicians at University Hospitals Case Medical Center enrolled their first patients in the ROADSTER Study, a global, multicenter clinical trial evaluating a novel, less-invasive procedure to help clear blockages in carotid arteries and prevent strokes.

19 Jun 2013

OncoSec Medical completes enrollment in ImmunoPulse trial for metastatic melanoma patients

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy and NeoPulse therapy to treat solid tumor cancers, announced the completion of patient enrollment in a Phase II clinical trial of ImmunoPulse for metastatic melanoma patients.

18 Jun 2013

Estrogen replacement therapy reduces anxiety symptoms in girls with anorexia nervosa

Estrogen replacement therapy is associated with a significant decrease in anxiety symptoms among girls with anorexia nervosa, a new clinical trial finds. The results will be presented today at The Endocrine Society's Annual Meeting in San Francisco.

18 Jun 2013

Study: Whole body vibration therapy raises bone strength among adolescents with cerebral palsy

A treatment known as whole body vibration therapy significantly increases bone strength among adolescents with cerebral palsy, a new clinical trial from New Zealand shows. The results were presented Saturday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Clinical Trial News and Research

HSG conducts clinical trial with novel drug formulation for treating Huntington disease

Comprehend Systems collaborates with Merge eClinical to expands its clinical research space

New $11 million grant for lowering stroke risk among black and young populations

New treatment option for patients with aortic stenosis

Laughing gas is associated with increased risk for perioperative cardiac events

Medicago produces Rotavirus VLP vaccine candidate using plant-based manufacturing platform

BerGenBio AS starts Phase 1 Clinical Trial for BGB324 oral AXL inhibitor

Banyan Biomarkers completes $6 million series A funding for further biomarker research

Researchers launch clinical trial on stem cells to prevent amputations in end stage PAD

Bristol-Myers Squibb and AstraZeneca announce top line results of Phase 4 SAVOR-TIMI-53 clinical trial of Onglyza

Pharma IQ releases new infographic summary of results from industry survey

Ico Therapeutics completes Phase 2 iDEAL study for treatment of diabetic macular edema

New framework to improve safety and effectiveness of surgical procedures, implantable devices

Patient enrollment and trial duration heavily impact the total cost of Phase 1 oncology trial

Signaling pathway correlates with EGFR status and poor survival in breast cancer patients

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

UHCMC physicians design new procedure to clear blocked carotid arteries, prevent stroke

OncoSec Medical completes enrollment in ImmunoPulse trial for metastatic melanoma patients

Estrogen replacement therapy reduces anxiety symptoms in girls with anorexia nervosa

Study: Whole body vibration therapy raises bone strength among adolescents with cerebral palsy

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