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Combination of BRAF-targeted therapy and immunotherapy shows promise for treatment of melanoma

Combined targeted therapy against the BRAF/MAPK pathway with immunotherapy shows promise as a new therapeutic approach for the treatment of melanoma, according to results of a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research.

16 Jun 2010

ISB, GIND collaborate on whole-genome sequencing to identify drug targets for Huntington's Disease

The Institute for Systems Biology (ISB) of Seattle, WA, is collaborating with the Gladstone Institute of Neurological Disease (GIND) and its Taube-Koret Center for Huntington's Disease Research to use whole-genome sequencing to identify genes and novel drug targets related to the onset and progression of Huntington's disease (HD). The research team, led by GIND associate director and senior investigator Steven Finkbeiner, MD, PhD, will also use induced pluripotent stem (iPS) cells from patients with HD to screen for drugs that might delay, prevent, or even reverse this devastating condition.

16 Jun 2010

Topical NSAIDs are safe and effective for acute pain: Researchers

Gels, creams and sprays containing painkillers such as ibuprofen, diclofenac, ketoprofen, and piroxicam are safe and effective treatments for local pain, according to Cochrane Researchers. A new systematic review they have conducted shows that topical non-steroidal anti-inflammatory drugs are more effective than placebos for treating short-term pain and have few side effects.

16 Jun 2010

Vitamin D may help reduce incidence, severity of viral respiratory tract infections: Study

Vitamin D may help reduce the incidence and severity of viral respiratory tract infections including influenza, according to a new study conducted by investigators at Greenwich Hospital and Yale University School of Medicine.

16 Jun 2010

Sanofi-aventis signs definitive agreement to acquire assets of Canderm

Sanofi-aventis announced today that it has entered into a definitive agreement under which an affiliate of sanofi-aventis Canada Inc. is to acquire the assets of Canderm Pharma Inc., a privately-held leading Canadian skin care company. This agreement is consistent with the sanofi-aventis Group's global strategy to expand its consumer health care growth platform and follows on the heels of the Group's acquisition of the North American CHC company Chattem Inc. in March 2010.

16 Jun 2010

Tips for correct application of sunscreen

You've gotten the message about the importance of sun protection, you're stocked up on sunscreen that's at least 15 SPF, and you're diligent about putting it on before you head outside. Once you've gotten this far, there's no reason to risk sunburns by applying it incorrectly. But, all too often, that's exactly what happens, says a Saint Louis University dermatologist.

15 Jun 2010

First patient treated in multicentre Phase I clinical trial of SCIB1 DNA ImmunoBody vaccine for melanoma

Scancell Holdings Plc,, the developer of therapeutic cancer vaccines, today announces the enrolment and treatment of the first patient in its multicentre Phase I clinical trial of SCIB1, its DNA ImmunoBody® vaccine being developed for the treatment of melanoma. The trial will evaluate the safety and tolerability of SCIB1 in patients with late stage melanoma.

15 Jun 2010

UH, AOA partner to get the word out about summer eye care, protection against UVR

As summer approaches, most people step up skin protection from harmful ultraviolet rays, yet aren't as vigilant about their eyes. Optometrists at the University of Houston are involved in a campaign to change this way of thinking.

15 Jun 2010

Xoft reports clinical benefits of isotope-free electronic radiation therapy for treatment of cancer

The clinical benefits of isotope-free electronic radiation therapy delivered directly to cancer sites with minimal exposure to surrounding healthy tissue continues to be substantiated by multiple publications, according to Xoft, Inc., developer of the Axxent Electronic Brachytherapy, eBx System. The leading provider of FDA-cleared Electronic Brachytherapy Systems, Xoft provides systems for single-dose intraoperative radiation therapy and accelerated brachytherapy applications.

15 Jun 2010

Researchers discover how bacteria boost the immune system

Scientists have long known that certain types of bacteria boost the immune system. Now, Loyola University Health System researchers have discovered how bacteria perform this essential task.

15 Jun 2010

ConvaTec presents Vitala Continence Control Device Phase 2 data at 2010 WOCN/WCET joint conference

ConvaTec, a world-leading developer of innovative medical technologies for community and hospital care, today presented data supporting the safety and efficacy of Vitala™, a novel, non-intrusive pouchless ostomy device that provides temporary continence to people with a colostomy. The clinical trial data were presented at the 2010 Joint Conference of the Wound, Ostomy and Continence Nurses Society (WOCN) and World Council of Enterostomal Therapists (WCET), where the new device is being previewed to U.S. and global healthcare professionals.

15 Jun 2010

New form of artificial human skin

Australian researchers are on the road to the discovery of a new form of artificial human skin that could be a boon to burn victims and other patients needing skin grafts. At present the available skin grafts are only 1 millimeter thick and serve only to replace the top epidermis layer.

14 Jun 2010

New path involving "innocent spectators" to defeat systemic sclerosis

There is a new path to defeat systemic sclerosis, also called scleroderma because of the hardening of the skin of the patients (from Greek skleros, "hard", and derma, "skin"). This path involves the B-cell of the immune system, so far only considered "innocent spectators," as Catholic University rheumatologist Gianfranco Ferraccioli, among the authors of the important research, puts it.

14 Jun 2010

WoundVision launches bedside thermographic imaging system

WoundVision™, the healthcare industry pioneer in advanced wound detection technology, is introducing today a revolutionary predictive bedside thermographic imaging system. The WoundVision system brings knowledge bedside by acquiring, analyzing and applying essential patient data to inform healthcare providers in the development of effective treatment and care plans.

14 Jun 2010

First step towards legally binding treaty to control mercury pollution completed at INC meeting

World governments, under the auspices of the United Nations Environment Programme, today completed the first step towards a legally binding treaty to control mercury pollution at the first Intergovernmental Negotiating Committee meeting, in Stockholm, Sweden. These initial discussions will provide a strong basis for developing the text of the treaty, starting at the next INC meeting in Tokyo, Japan, January 2011.

14 Jun 2010

Children born after ART at increased risk of congenital malformation

Couples considering undergoing assisted reproductive technology (ART) treatment should be informed about the increased risk of congenital malformation posed by the use of ART, the annual conference of the European Society of Human Genetics will hear today (Monday). Dr. G-raldine Viot, a clinical geneticist at the Maternit- Port Royal hospital, Paris, France, will say that she believed that most doctors working in ART clinics in France only told couples about such risks if they were asked specific questions.

14 Jun 2010

New SACS Instrument launched to assess and classify peristomal skin lesions

A new evidence-based instrument to assess and classify peristomal skin lesions was launched at the 2010 Joint Conference of the Wound, Ostomy and Continence Nurses Society and World Council of Enterostomal Therapists. The instrument, known as the SACS Instrument, represents the first content-validated instrument to objectively assess and classify peristomal lesions by type and location in relation to an individual's stoma.

14 Jun 2010

Australian rainforests may provide potential cancer cure

Queensland scientists have discovered a drug to cure cancer that has effectively worked in animals and is to be tried on humans in the next phase of trials. This drug is plant-derived and is called EBC-46 for trial purposes. The plant from which it is obtained is found in the Australian tropical rainforest. The drug has shown to reduce inoperable tumors in 150 dogs, cats and horses and a ferret to a significant extent. The drug was developed over the past six years from the seed of a rainforest plant found in the Atherton Tablelands. Scientists had cultivated their own plantation of the plant since forming the company QBiotics Limited in 2004.

14 Jun 2010

In vitro fertilization ups the risk of birth defects: study

Researchers have found from a large scale study that in vitro fertilization of IVF is associated with an increased risk of birth defects in the baby. They urge doctors treating patients with infertility to routinely warn them about these risks. The study involved 33 centers for IVF in France and covered over 15,000 births from 2003 to 2007. This study is the largest till date.

14 Jun 2010

3M Health Care launches new foam adhesive dressings for acute and chronic wounds

3M Health Care today announced the introduction of a full line of new, innovative Tegaderm™ High Performance Foam Adhesive Dressings. In clinical and laboratory tests, these new adhesive foam wound dressings outperform other leading foam adhesive dressings in managing the full range of low- to high-moisture conditions that can be present in chronic and acute wounds.

14 Jun 2010

Skin News and Research

Combination of BRAF-targeted therapy and immunotherapy shows promise for treatment of melanoma

ISB, GIND collaborate on whole-genome sequencing to identify drug targets for Huntington's Disease

Topical NSAIDs are safe and effective for acute pain: Researchers

Vitamin D may help reduce incidence, severity of viral respiratory tract infections: Study

Sanofi-aventis signs definitive agreement to acquire assets of Canderm

Tips for correct application of sunscreen

First patient treated in multicentre Phase I clinical trial of SCIB1 DNA ImmunoBody vaccine for melanoma

UH, AOA partner to get the word out about summer eye care, protection against UVR

Xoft reports clinical benefits of isotope-free electronic radiation therapy for treatment of cancer

Researchers discover how bacteria boost the immune system

ConvaTec presents Vitala Continence Control Device Phase 2 data at 2010 WOCN/WCET joint conference

New form of artificial human skin

New path involving "innocent spectators" to defeat systemic sclerosis

WoundVision launches bedside thermographic imaging system

First step towards legally binding treaty to control mercury pollution completed at INC meeting

Children born after ART at increased risk of congenital malformation

New SACS Instrument launched to assess and classify peristomal skin lesions

Australian rainforests may provide potential cancer cure

In vitro fertilization ups the risk of birth defects: study

3M Health Care launches new foam adhesive dressings for acute and chronic wounds

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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