Clinical Trial News and Research

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Understanding Phelan-McDermid Syndrome

In the first prospective study of its kind, Seaver Autism Center researchers at the Icahn School of Medicine at Mount Sinai provide new evidence of the severity of intellectual, motor, and speech impairments in a subtype of autism called Phelan-McDermid Syndrome.

12 Jun 2013

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Advanced metastatic melanoma is a disease that has proven difficult to eradicate. Despite the success of melanoma-targeting drugs, tumors inevitably become drug resistant and return, more aggressive than before. In the current issue of the journal Cancer Cell, however, researchers at The Wistar Institute describe how they increase the effectiveness of anti-melanoma drugs by combining anticancer therapies with diabetes drugs.

12 Jun 2013

Clinical trial underway for potential new treatment for type 1 diabetes

A clinical trial is underway for a potential new treatment for type 1 diabetes that could eventually mean patients are able to reduce insulin treatment from several times a day to only once or twice a week. The new treatment is a direct result of research to understand the genetics of the disease.

11 Jun 2013

Cerus enrolls patient in two European clinical trials for INTERCEPT System for RBCs

Cerus Corporation announced today that it has initiated patient enrollment in two European Phase III clinical trials for the INTERCEPT System for red blood cells.

11 Jun 2013

Abbott starts ABSORB Japan trial to evaluate Absorb BVS in patients with CAD

Abbott today announced that it has initiated the ABSORB Japan randomized controlled clinical trial to evaluate the Absorb Bioresorbable Vascular Scaffold in patients with coronary artery disease, the most common form of heart disease.

11 Jun 2013

Medicago gets Health Canada clearance to initiate Phase II clinical trial for H5N1 vaccine

Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles, today announced it has received clearance by Health Canada to initiate its Phase II dose-sparing clinical trial for an H5N1 Avian Influenza VLP vaccine candidate ("H5N1 vaccine").

11 Jun 2013

Combination of cell-killing radioactive particle and antibody is safe for treating cancers

An experimental treatment that combines a cell-killing radioactive particle with an antibody that homes in on cancer cells is safe in the treatment of cancers spreading through patients' abdomens, according to data from a first-in-human study presented today at the Society of Nuclear Medicine and Molecular Imaging annual meeting in Vancouver.

11 Jun 2013

Rapamycin improves cardiac function in mice suffering from age-related heart disease

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months.

11 Jun 2013

Using stress CMR imaging for patients with acute chest pain is a win-win situation, say doctors

Wake Forest Baptist Medical Center doctors have found that using stress cardiac magnetic resonance (CMR) imaging in an Emergency Department observation unit to care for patients with acute chest pain is a win-win - for the patient and the institution.

11 Jun 2013

International clinical study shows that BioProtect Balloon Implant has potential to reduce rectal injury

Several years ago, Virginia Commonwealth University Massey Cancer Center became the first center in the United States to test an Israeli-invented device designed to increase the space between the prostate and the rectum in prostate cancer patients undergoing radiation therapy.

11 Jun 2013

Concert Pharmaceuticals announces initiation of CTP-354 Phase 1 trial in healthy volunteers

Concert Pharmaceuticals, Inc. today announced that it has initiated a Phase 1 clinical trial with CTP-354. CTP-354 is a novel GABAA receptor subtype-selective modulator that has demonstrated no sedation at therapeutic doses in preclinical models in contrast to existing GABAA receptor non-selective agonists, such as benzodiazepines.

10 Jun 2013

Exact Sciences announces submission of final module of PMA application to FDA for Cologuard

Exact Sciences Corp. today announced that it has submitted to the U.S. Food and Drug Administration the final module of the premarket approval application for Cologuard, the company's stool DNA (sDNA) colorectal cancer screening test.

10 Jun 2013

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.

10 Jun 2013

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Edge Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products for acute, fatal or debilitating conditions, announced today that the U.S. Food and Drug Administration has accepted the Company's Investigational New Drug application for EG-1962, a novel bio-absorbable nimodipine microparticle formulation.

10 Jun 2013

Faldaprevir+ achieves viral cure in 88% of treatment-naïve genotype-1 hepatitis C patients in Asia

New findings presented today during the APASL Liver Week in Singapore, highlighted the efficacy and safety of faldaprevir+ plus pegylated interferon and ribavirin (PegIFN/RBV) in treatment-naïve patients with genotype-1 hepatitis C virus (HCV) in Asia.1 This post-hoc sub-analysis of the Phase III STARTVerso™1 and 2 trials showed that both doses of faldaprevir were associated with high viral cure rates and a shorter treatment duration in this particular patient group.1

10 Jun 2013

First consensus guidelines for use of neurostimulation in chronic pain

Recognizing that treatment of chronic pain can be confounding, the Neuromodulation Appropriateness Consensus Committee, an international group of more than 60 leading pain specialists, has created the first consensus guidelines for the use of neurostimulation in chronic pain.

10 Jun 2013

Cedars-Sinai opens Phase III clinical trial for patients with intestinal carcinoid cancer

Working to improve treatment and survivorship outcomes, the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute has opened a Phase III clinical trial of targeted radiation for patients with intestinal carcinoid cancer that has spread beyond the intestine.

10 Jun 2013

Clinical Trial News and Research

Understanding Phelan-McDermid Syndrome

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Clinical trial underway for potential new treatment for type 1 diabetes

Cerus enrolls patient in two European clinical trials for INTERCEPT System for RBCs

Abbott starts ABSORB Japan trial to evaluate Absorb BVS in patients with CAD

Medicago gets Health Canada clearance to initiate Phase II clinical trial for H5N1 vaccine

Combination of cell-killing radioactive particle and antibody is safe for treating cancers

Rapamycin improves cardiac function in mice suffering from age-related heart disease

Using stress CMR imaging for patients with acute chest pain is a win-win situation, say doctors

International clinical study shows that BioProtect Balloon Implant has potential to reduce rectal injury

Concert Pharmaceuticals announces initiation of CTP-354 Phase 1 trial in healthy volunteers

Exact Sciences announces submission of final module of PMA application to FDA for Cologuard

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Faldaprevir+ achieves viral cure in 88% of treatment-naïve genotype-1 hepatitis C patients in Asia

First consensus guidelines for use of neurostimulation in chronic pain

Cedars-Sinai opens Phase III clinical trial for patients with intestinal carcinoid cancer

Large study of deep brain stimulation underway for Alzheimer's disease treatment

Genetic testing of chronic neutrophilic leukemia reveals presence of new mutation in patients

Doctors create bioengineered blood vessel and implant it in the arm of kidney disease patient

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