Immune System News and Research

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Small airway-on-a-chip enables analysis of human COPD and asthma

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University leveraged its organ-on-a-chip technology to develop a model of the human small airway in which lung inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), the third leading cause of mortality worldwide, and asthma can be studied outside the human body.

22 Dec 2015

UM student awarded grant for research on human immune system

A hardworking University of Montana undergraduate student will spend the next two and half years studying the hardest-working cell in the human immune system.

22 Dec 2015

Patients with EGFR-mutated lung cancer benefit more from afatinib as first-line treatment

Patients with EGFR-activating mutations in advanced lung cancer seem to benefit more from afatinib than gefitinib as first-line treatment, researchers report at the first ESMO Asia 2015 Congress in Singapore.

21 Dec 2015

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

A group of Russian scientists, including Dr Elena Kostryukova, the Head of the Laboratory of Postgenomic Research in Biology of the Scientific Research Institute of Physical-Chemical Medicine and a researcher at MIPT (Moscow Institute of Physics and Technology), and Maria Vakhitova, an MIPT postgraduate student, has discovered that the presence of certain bacteria in the gut may be linked to the development of type 2 diabetes.

21 Dec 2015

Flu vaccine: the facts. An interview with Dr Lisa Maragakis

There are different formulations of the flu vaccine but in general they all do the same thing, which is to stimulate our body's immune system to recognize and fight against the influenza virus.

21 Dec 2015

GeNeuro initiates GNbAC1 Phase IIb study in Relapsing-Remitting Multiple Sclerosis

GeNeuro SA, a pioneer of new therapies for neurology and autoimmune disorders, announced today that it has initiated its planned Phase IIb study “CHANGE-MS” (Clinical trial assessing the HERV-W Env ANtagonist GNbAC1 for Efficacy in Multiple Sclerosis) with its lead antibody GNbAC1 in Relapsing-Remitting Multiple Sclerosis (RRMS).

21 Dec 2015

Australian researchers develop new technique to combat chronic bacterial infections in hospitals

One of the scourges of infections in hospitals – biofilms formed by bacteria that stick to each other on living tissue and medical instruments, making them harder to remove – can be tricked into dispersing with the targeted application of nanoparticles and heat, researchers have found.

21 Dec 2015

Janssen collaborates with Bavarian Nordic to develop, commercialize vaccine for chronic HPV infections

Janssen Pharmaceuticals, Inc. announced today that the company has entered into a definitive collaboration and license agreement with Bavarian Nordic to leverage their MVA-BN technology, jointly with Janssen's own AdVac® technology, in the development and commercialization of a heterologous prime-boost vaccine for the treatment of Human Papillomavirus (HPV) chronic infections which can lead to cancer.

20 Dec 2015

Novel drug candidate prevents nerve cell damage in mouse model of Parkinson's disease

A team of scientists at the University of Nebraska Medical Center (UNMC) and Longevity Biotech, Inc., has demonstrated that neuroprotection could be attained in preclinical models by a novel drug candidate that changes immune responses.

18 Dec 2015

Findings show promising evidence for creating broad-spectrum antiviral

UW researchers working in collaboration with Kineta Inc. and the University of Texas at Galveston have shown that making a drug-like molecule to turn on innate immunity can induce genes to control infection in several -known viruses.

18 Dec 2015

New discovery could open door to potential treatment for West Nile virus and Dengue virus infections

A new discovery from the University of Alberta's Faculty of Medicine & Dentistry could open the door to one day treat or prevent diseases caused by West Nile virus and Dengue virus infections.

18 Dec 2015

Patient's mental health prior to radical cystectomy can influence postoperative outcomes

A patient's mental health prior to surgery can influence postoperative outcomes. Removal of the bladder, or radical cystectomy (RC), is an effective treatment for locally advanced bladder cancer, but complications occur in as many as 66% of patients.

18 Dec 2015

Research opens door to validation studies in multiple tumor types of liquid biopsy

Pancreatic cancer tumors spill their molecular secrets into the blood stream, shedding their complete DNA and RNA wrapped inside protective lipid particles that make them ripe for analysis with a liquid biopsy, researchers at The University of Texas MD Anderson Cancer Center report online at the Annals of Oncology.

18 Dec 2015

Zoledronate drug can protect stem cells from ageing

Stem cells can be protected from the effects of ageing by a drug currently used to treat patients with osteoporosis, a breakthrough study has found.

17 Dec 2015

CRCHUM researchers find mechanism responsible for rejection of organ transplants

A new cellular structure responsible for previously unexplained rejection of organ transplants has been identified by researchers at the University of Montreal Hospital Research Centre.

17 Dec 2015

Cardiff scientists find way to aid recovery, reduce risk of life-threatening infections in brain damaged patients

Cardiff University scientists believe they may have found a way to aid recovery and minimise the risk of life-threatening infections in patients with traumatic brain injuries.

17 Dec 2015

Feeling sad can alter levels of inflammatory proteins linked to increased risk of comorbid diseases

Feeling sad can alter levels of stress-related opioids in the brain and increase levels of inflammatory proteins in the blood that are linked to increased risk of comorbid diseases including heart disease, stroke and metabolic syndrome, according to a study by researchers at The University of Texas Health Science Center at Houston.

17 Dec 2015

Oxford research programmes to explore link between metabolism, inflammation in metabolic diseases

Two innovative Oxford research programmes will explore the relationship between metabolism and inflammation in metabolic diseases. Obesity, insulin resistance, type 2 diabetes (T2D) and associated cardiovascular disease (CVD) -- all metabolic diseases -- are an epidemic global health problem.

17 Dec 2015

Researchers identify how immune cells triggered by recurrent Strep A infections affect the brain

Researchers have discovered how immune cells triggered by recurrent Strep A infections enter the brain, causing inflammation that may lead to autoimmune neuropsychiatric disorders in children.

16 Dec 2015

Human-gut-on-a-chip model offers hope for patients suffering from IBD

It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst can lead to life-threatening complications.

16 Dec 2015

Immune System News and Research

Small airway-on-a-chip enables analysis of human COPD and asthma

UM student awarded grant for research on human immune system

Patients with EGFR-mutated lung cancer benefit more from afatinib as first-line treatment

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

Flu vaccine: the facts. An interview with Dr Lisa Maragakis

GeNeuro initiates GNbAC1 Phase IIb study in Relapsing-Remitting Multiple Sclerosis

Australian researchers develop new technique to combat chronic bacterial infections in hospitals

Janssen collaborates with Bavarian Nordic to develop, commercialize vaccine for chronic HPV infections

Novel drug candidate prevents nerve cell damage in mouse model of Parkinson's disease

Findings show promising evidence for creating broad-spectrum antiviral

New discovery could open door to potential treatment for West Nile virus and Dengue virus infections

Patient's mental health prior to radical cystectomy can influence postoperative outcomes

Research opens door to validation studies in multiple tumor types of liquid biopsy

Zoledronate drug can protect stem cells from ageing

CRCHUM researchers find mechanism responsible for rejection of organ transplants

Cardiff scientists find way to aid recovery, reduce risk of life-threatening infections in brain damaged patients

Feeling sad can alter levels of inflammatory proteins linked to increased risk of comorbid diseases

Oxford research programmes to explore link between metabolism, inflammation in metabolic diseases

Researchers identify how immune cells triggered by recurrent Strep A infections affect the brain

Human-gut-on-a-chip model offers hope for patients suffering from IBD

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