Efficacy News and Research

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Lilly announces positive results from LY2951742 Phase 2b study in patients with episodic migraine

Eli Lilly and Company announced today that its investigational medicine for prevention of migraine (LY2951742, a CGRP neutralizing antibody) met the primary endpoint in a Phase 2b study in episodic migraine.

19 Jun 2015

International researchers identify previously unknown genetic immunodeficiency

An analysis of five families has revealed a previously unknown genetic immunodeficiency, says an international team led by researchers from Boston Children's Hospital. The condition, linked to mutations in a gene called DOCK2, deactivates many features of the immune system and leaves affected children open to a unique pattern of aggressive, potentially fatal infections early in life.

19 Jun 2015

Florida Institute finalizes funding agreement with TransGenex Nanobiotech

The Florida Institute for the Commercialization of Public Research announced today that it has finalized a funding agreement with TransGenex Nanobiotech, Inc., a company that is developing nano-scale technologies for novel, cost-effective diagnostic and therapeutic agents against cancers and other inflammatory diseases.

19 Jun 2015

Patient survival rates for home hemodialysis significantly higher than peritoneal dialysis

NxStage Medical, Inc. is encouraging patients to take control of their dialysis therapy and consider home hemodialysis in the wake of a new study that found patient survivability rates are significantly higher with home hemodialysis (HHD) than peritoneal dialysis (PD).

18 Jun 2015

Scientists reveal new combination method that efficiently destroys cancer cells

Scientists at the Institut Pasteur and Inserm have successfully increased the infiltration of immune cells into tumors, thus inducing the immune system to block tumor growth. In an article published in Nature Immunology, the scientists show that, in combination with existing immunotherapies, this process efficiently destroys cancer cells.

18 Jun 2015

Study suggests that dried plums may help support healthy bones

The International Symposium on Nutritional Aspects of Osteoporosis brings together the best scientific minds in bone health research and nutrition. Current research presented at the 2015 Ninth ISNAO has added to the increasing body of evidence that suggests dried plums (prunes) help to support healthy bones and may even promote attainment of peak bone mass.

18 Jun 2015

New article shows taxonomic classification of rare genetic bone disorders based on metabolic phenotypes

An International Osteoporosis Foundation Working Group on Skeletal Rare Diseases has published a new classification of rare genetic metabolic bone disorders (RGMBDs) according to their metabolic pathogenesis.

18 Jun 2015

Highly efficient ChIP assay kit for FFPE samples

Chromatrap®, a business unit of Porvair Sciences, has introduced a new Formaldehyde Fixed Paraffin-Embedded (FFPE) ChIP Kit which overcomes the widely acknowledged shortfalls of the technique.

From Chromatrap® - Porvair Sciences Ltd 17 Jun 2015

Bivalent HPV vaccine efficacy may be independent of dose

Fewer than three doses of the bivalent human papillomavirus vaccine may be sufficient to offer adequate protection against cervical HPV-16 and -18 infection, research published in The Lancet Oncology indicates.

17 Jun 2015

CGRP monoclonal antibodies show promise in treating migraine

Migraine researchers and clinicians are growing excited about a new class of drugs called Calcitonin Gene-Related Peptide (CGRP) monoclonal antibodies, which are showing promise in treating high-frequency episodic migraine and chronic migraine.

17 Jun 2015

Antibiotic treatment not better than appendectomy for uncomplicated acute appendicitis

Among patients with uncomplicated appendicitis, antibiotic treatment did not meet a prespecified level of effectiveness compared with appendectomy, although most patients who received antibiotic therapy did not require an appendectomy, and for those who did, they did not experience significant complications, according to a study in the June 16 issue of JAMA.

17 Jun 2015

Earthquake-ravaged Nepal faces 'very high' risk of hepatitis E outbreak

During the coming monsoon season, survivors of the recent earthquake that destroyed parts of Nepal face a "very high" risk of a hepatitis E outbreak that could be especially deadly to pregnant women, according to a consensus statement from a group of infectious disease experts from around the world.

17 Jun 2015

Elekta's Esteya electronic brachytherapy improves outcomes in patients with basal cell carcinoma

Physicians at La Fe University and Polytechnic Hospital - Valencia presented their early clinical outcome data on the use of Esteya electronic brachytherapy for the treatment of basal cell carcinoma in a paper in the current issue of Journal of Contemporary Brachytherapy. The ongoing study showed 100 percent complete response and excellent cosmetic outcome in all lesions treated to date with Esteya.

From Elekta 17 Jun 2015

MGH-CEM researchers develop novel approach to evaluate the liver's drug-metabolizing activity

A team of researchers from the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) has developed a novel approach that dramatically simplifies the evaluation of the liver's drug-metabolizing activity and the potential toxic effects of the products of that activity on other organs.

17 Jun 2015

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

CQDM and Ontario Centres of Excellence will fund five highly innovative and unconventional game-changing research and development projects to accelerate drug discovery in the Quebec-Ontario Life Sciences Corridor. Partners are granting $1.5M to Quebec-based and, for the first time, Ontario-based researchers thanks to the partnership with OCE through CQDM's 2014 Explore Program, one of CQDM's flagship programs focusing on early concept validation of cutting-edge technologies that address the most crucial needs in drug discovery and development.

17 Jun 2015

GOJO SMARTLINK OBV System launched for collecting hand hygiene and PPE compliance metrics

GOJO Industries, the inventors of PURELL Advanced Hand Sanitizer, announced today that it has launched its GOJO SMARTLINK Observation (OBV) System, a mobile application that connects to GOJO SMARTLINK web-based software and allows for the electronic collection and collation of hand hygiene and PPE compliance metrics.

16 Jun 2015

New data shows psychotropic medication use among Medicaid-enrolled foster children in Pennsylvania

Today, the Department of Human Services, in partnership with PolicyLab at The Children's Hospital of Philadelphia, released new data on psychotropic medication use among Medicaid-enrolled Pennsylvania children in foster care, as well as the state's action plan to address the findings.

16 Jun 2015

PNP Therapeutics granted FDA orphan drug designation for Gedeptin

PNP Therapeutics Inc. announced today the Food and Drug Administration has granted orphan drug status to Gedeptin, the Company's lead product candidate (adenoviral vector expressing E. coli purine nucleoside phosphorylase gene) for the intratumoral treatment of anatomically accessible oral and pharyngeal cancers, including cancers of the lip, tongue, gum, floor of mouth, salivary gland and other oral cavities.

16 Jun 2015

Genticel’s GTL001 phase 1 clinical study of HPV therapeutic vaccine granted FDA clearance

Genticel, a French biotechnology company and developer of innovative immunotherapies to prevent cancers caused by the human papillomavirus, today announces that the US Food and Drug Administration (FDA) has cleared Genticel’s Investigational New Drug application to conduct in the US a phase 1 clinical study of GTL001 in patients infected with HPV 16 and/or 18, the two HPV types responsible for 70% of cervical cancer cases.

16 Jun 2015

Pulmatrix announces new inhaled anti-infective therapy to treat CF-associated fungal infections

Pulmatrix, Inc., a clinical stage biopharmaceutical company developing innovative inhaled therapies for serious pulmonary diseases, today announced a new drug candidate, PUR1900, an inhaled anti-infective to treat fungal infections associated with cystic fibrosis (CF).

16 Jun 2015

Efficacy News and Research

Lilly announces positive results from LY2951742 Phase 2b study in patients with episodic migraine

International researchers identify previously unknown genetic immunodeficiency

Florida Institute finalizes funding agreement with TransGenex Nanobiotech

Patient survival rates for home hemodialysis significantly higher than peritoneal dialysis

Scientists reveal new combination method that efficiently destroys cancer cells

Study suggests that dried plums may help support healthy bones

New article shows taxonomic classification of rare genetic bone disorders based on metabolic phenotypes

Highly efficient ChIP assay kit for FFPE samples

Bivalent HPV vaccine efficacy may be independent of dose

CGRP monoclonal antibodies show promise in treating migraine

Antibiotic treatment not better than appendectomy for uncomplicated acute appendicitis

Earthquake-ravaged Nepal faces 'very high' risk of hepatitis E outbreak

Elekta's Esteya electronic brachytherapy improves outcomes in patients with basal cell carcinoma

MGH-CEM researchers develop novel approach to evaluate the liver's drug-metabolizing activity

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

GOJO SMARTLINK OBV System launched for collecting hand hygiene and PPE compliance metrics

New data shows psychotropic medication use among Medicaid-enrolled foster children in Pennsylvania

PNP Therapeutics granted FDA orphan drug designation for Gedeptin

Genticel’s GTL001 phase 1 clinical study of HPV therapeutic vaccine granted FDA clearance

Pulmatrix announces new inhaled anti-infective therapy to treat CF-associated fungal infections

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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