Genes News and Research

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Researchers find novel gene in red blood cells that may help limb regeneration in adult newts

Newts are the only four-legged vertebrates that can regenerate their body parts even as adults. When a newt loses a limb, a mass of cells, called a blastema, is generated at the stump, from which a new, fully functional limb is eventually regenerated.

5 Jun 2018

Researchers discover how the heart becomes fully developed

Researchers have discovered how the heart develops from a simple tube into its characteristic S-shape and forms ventricles and atria.

4 Jun 2018

MDC researchers provide new insights on embryonic heart development

When it first starts to develop, the heart is a simple tube. Reporting in the journal Nature Communications, researchers at MDC have now described how it forms itself into a its characteristic S-shape and how the ventricles and atria finally develop.

4 Jun 2018

Researchers discover new medicine that may fight against monogenic obesity

Around two to six per cent of all people with obesity develop obesity already in early childhood; it's in their genetic cards.

4 Jun 2018

Genomic markers can predict lynch syndrome across tumor types

Microsatellite instability and DNA mismatch repair deficiencies can predict Lynch syndrome across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center, who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2018

African-American men with prostate cancer show stronger response to hormone therapy

African-American men with advanced prostate cancer might be more responsive than white men to an anti-androgen drug and steroids, according to a study led by Duke Cancer Institute researchers.

4 Jun 2018

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the "stemness" of chronic leukemia cancer cells - their ability to self-renew and resist terminal differentiation and senescence.

1 Jun 2018

Study: Few men undergo genetic testing despite high risk of breast cancer

Cancer is one of the leading causes of death among Americans. At least 10 percent of cancers are caused by inherited mutations in genes such as BRCA1 and BRCA2. Parents with the cancer gene mutation have a 50 percent chance of passing it on to a son or daughter.

1 Jun 2018

Researchers reveal role NAD+ molecule in turning on genes that make fat cells

Glucose is the energy that fuels cells, and the body likes to store glucose for later use. But too much glucose can contribute to obesity, and scientists have long wanted to understand what happens within a cell to tip the balance.

1 Jun 2018

Researchers discover three genes that may have contributed to evolution of large human brain

Three genes involved in nerve cell generation in the brain emerged roughly 3.5 million years ago and may have contributed to the rapid evolution of the large human brain, Howard Hughes Medical Institute (HHMI) Investigator David Haussler and colleagues report on May 31, 2018, in the journal Cell.

1 Jun 2018

Study highlights complexity of the brain’s molecular response to cocaine use

A study in Biological Psychiatry has identified unique genetic changes in the brain's reward circuitry that are associated with cocaine use, including first-time use, withdrawal, and re-exposure to the drug after prolonged withdrawal.

31 May 2018

Scientists uncover the role of the ApoE gene in Alzheimer's Disease

A study conducted at the Massachusetts Institute of Technology has identified why the ApoE4 gene increases the risk of developing Alzheimer's disease, and why the ApoE3 gene reduces the risk.

31 May 2018

New study finds Greenlandic children to be taller than before

For centuries Inuit children in Greenland, Canada, and Alaska have been observed as small. But recently they have begun to grow a lot.

31 May 2018

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Treating inflammatory diseases of the bowel is extremely challenging: Genes, gut microbes and disrupted immune function all contribute.

31 May 2018

Agendia and Angsana partner to market MammaPrint, BluePrint breast cancer tests in Southeast Asia

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, and Angsana Molecular & Diagnostics Laboratory Pte Ltd, a subsidiary of Parkway Pantai, announce a partnership to market the MammaPrint Breast Cancer Risk of Recurrence test and the BluePrint Molecular Subtyping test to physicians across Southeast Asia, including Singapore, Malaysia, Vietnam, Brunei and Myanmar.

31 May 2018

New RNA deletion tool could help create drugs that correct genetic diseases

As scientists gain insights into which genes drive diseases, they are pursuing the next logical question: Can gene editing technologies be developed to treat or even cure those diseases? Much of that effort has focused on developing technologies such as CRISPR-Cas9, a protein-based system.

30 May 2018

Defective energy production may explain why our brains are prone to age-related diseases

Defective energy production in old neurons might explain why our brains are so prone to age-related diseases.

30 May 2018

New study shows that epigenetic silencing of genes limits eye development of cave fish

Loss of eye tissue in blind cavefish (Astyanax mexicanus), which occurs within a few days of their development, happens through epigenetic silencing of eye-related genes, according to a study led by the National Institutes of Health. Epigenetic regulation is a process where genes are turned off or on, typically in a reversible or temporary manner.

29 May 2018

Study proposes a new way to reverse the aging process

A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases - and possibly even turn back the clock on aging itself.

29 May 2018

Researchers develop innovative tool for female reproductive genetics

The fruit fly Drosophila melanogaster is a powerful model organism for studying animal and human development and disease. It is low cost, generates rapidly, and there are many tools to genetically modify its cells.

29 May 2018

Genes News and Research

Researchers find novel gene in red blood cells that may help limb regeneration in adult newts

Researchers discover how the heart becomes fully developed

MDC researchers provide new insights on embryonic heart development

Researchers discover new medicine that may fight against monogenic obesity

Genomic markers can predict lynch syndrome across tumor types

African-American men with prostate cancer show stronger response to hormone therapy

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Study: Few men undergo genetic testing despite high risk of breast cancer

Researchers reveal role NAD+ molecule in turning on genes that make fat cells

Researchers discover three genes that may have contributed to evolution of large human brain

Study highlights complexity of the brain’s molecular response to cocaine use

Scientists uncover the role of the ApoE gene in Alzheimer's Disease

New study finds Greenlandic children to be taller than before

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Agendia and Angsana partner to market MammaPrint, BluePrint breast cancer tests in Southeast Asia

New RNA deletion tool could help create drugs that correct genetic diseases

Defective energy production may explain why our brains are prone to age-related diseases

New study shows that epigenetic silencing of genes limits eye development of cave fish

Study proposes a new way to reverse the aging process

Researchers develop innovative tool for female reproductive genetics

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