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Cinnamon compound could be useful supplement to dexamethasone in COVID-19 treatment

Researchers in Germany and the United States have conducted a study showing that supplementing dexamethasone treatment with Ceylon cinnamon in cases of coronavirus disease 2019 (COVID-19) may allow dexamethasone to be administered at lower doses, thereby avoiding the side effects that occur with high doses of the steroid.

17 Jun 2021

Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response

Researchers reporting on findings from the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial in the UK are recommending that any therapeutic use of REGEN-COV may be best restricted to individuals without detectable antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Jun 2021

APOE ɛ4 carriers with midlife depressive symptoms may be at higher risk of tau accumulation

Middle-aged people with depressive symptoms who carry a genetic variation called apolipoprotein (APOE) ε4 may be more at risk to develop tau protein accumulations in the brain's emotion- and memory-controlling regions, a new study by researchers from The University of Texas Health Science Center at San Antonio and collaborating institutions suggests.

17 Jun 2021

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumors have faulty copies of the BRCA cancer genes.

17 Jun 2021

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

17 Jun 2021

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

The normal function of uromodulin, a protein that is made in the kidney and secreted into the urine, remains largely unknown. However, higher levels of uromodulin in the urine are related to lower rates of urinary tract infections and kidney stones, while higher levels of this protein in kidney cells are associated with higher rates of hypertension and chronic kidney disease.

17 Jun 2021

Novel ferritin nanoparticle vaccine candidate effective against SARS-CoV-2 variants in preclinical trials

A team of scientists from the United States has recently evaluated the efficacy of a ferritin nanoparticle-formulated, SARS-CoV-2 spike-based vaccine against newly emerged Variants of Concern (VOCs).

17 Jun 2021

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

In a new study, released as a preprint on the medRxiv* server, researchers from Germany, Italy and Netherlands demonstrated the utility of integrating genomic and wastewater based epidemiology (WBE) to provide unprecedented insight into the abundance of SARS-CoV-2 and the profile of the mutations associated with the VOCs (i.e., B.1.1.7, B.1.351, P.1, and B.1.617.2) in the wastewater samples.

17 Jun 2021

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

A new preprint recently released on the bioRxiv* server describes the immunogenicity and protective potential of a novel adenovirus SARS-CoV-2 vaccine candidate against a form of the virus adapted to cause severe disease in mice. The findings show that this provides a useful mouse model for the study of new vaccines, in addition to demonstrating the protective efficacy of the current rhesus adenovirus vaccine candidate RhAd52.

17 Jun 2021

How the common cold can provide protection against COVID-19

In a recent study, researchers found that prior infection with the rhinovirus can provide a more effective immune response against SARS-CoV-2 infection.

17 Jun 2021

Not all experts are ready to vaccinate kids against Covid

Lucien Wiggins, 12, arrived at Tufts Children's Hospital by ambulance June 7 with chest pains, dizziness and high levels of a protein in his blood that indicated inflammation of his heart. The symptoms had begun a day earlier, the morning after his second vaccination with the Pfizer-BioNTech mRNA shot.

17 Jun 2021

New noninvasive biomarker can be used in the diagnosis of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and can progress to liver cirrhosis, liver failure or cancer. Currently, nonalcoholic steatohepatitis (NASH) diagnosis requires an invasive liver biopsy which can lead to procedural complications.

17 Jun 2021

Dietary patterns of truck drivers linked with driving behaviors and crash risk

A junk food diet may increase the risk of dangerous driving among truck/lorry drivers by boosting fatigue, which is often a key factor in vehicle collisions, suggests research published online in the journal Occupational & Environmental Medicine.

17 Jun 2021

New computational technique greatly increases the resolution of atomic force microscopy

Scientists at Weill Cornell Medicine have developed a computational technique that greatly increases the resolution of atomic force microscopy, a specialized type of microscope that "feels" the atoms at a surface.

17 Jun 2021

Antibody combination REGEN-COV prevents symptomatic disease following SARS-CoV-2 infection

Researchers in the United States have demonstrated the effectiveness of early treatment with REGEN-COV™ at preventing symptomatic disease among people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

17 Jun 2021

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that the heart is unable to fill properly with blood.

17 Jun 2021

Study reveals potentially druggable process of SARS-Cov-2 assembly and replication

Of all the proteins of the SARS-CoV-2 virus (the pathogen that causes COVID-19), the spike protein is the one that gets the most attention.

17 Jun 2021

Precision medicine may lead to more effective treatments for ocular conditions

The most practical solution for drug delivery to the eyeball is topical, i.e. eye drops. However, a naturally occurring substance in tears actually can interact with the drug delivery system (DDS), hindering absorption of the drug and preventing it from getting into the cells it needs to target.

17 Jun 2021

Study sheds new light on the function of a sight-saving growth factor

Researchers at the National Eye Institute (NEI) have determined how certain short protein fragments, called peptides, can protect neuronal cells found in the light-sensing retina layer at the back of the eye.

17 Jun 2021

Researchers prepare for next coronavirus pandemic

Scientists are already preparing for a possible next coronavirus pandemic to strike, keeping with the seven-year pattern since 2004.

17 Jun 2021

Protein C News and Research

Cinnamon compound could be useful supplement to dexamethasone in COVID-19 treatment

Regeneron mAb cocktail benefits hospitalized patients with no natural SARS-CoV-2 antibody response

APOE ɛ4 carriers with midlife depressive symptoms may be at higher risk of tau accumulation

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

Novel ferritin nanoparticle vaccine candidate effective against SARS-CoV-2 variants in preclinical trials

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

How the common cold can provide protection against COVID-19

Not all experts are ready to vaccinate kids against Covid

New noninvasive biomarker can be used in the diagnosis of NAFLD

Dietary patterns of truck drivers linked with driving behaviors and crash risk

New computational technique greatly increases the resolution of atomic force microscopy

Antibody combination REGEN-COV prevents symptomatic disease following SARS-CoV-2 infection

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Study reveals potentially druggable process of SARS-Cov-2 assembly and replication

Precision medicine may lead to more effective treatments for ocular conditions

Study sheds new light on the function of a sight-saving growth factor

Researchers prepare for next coronavirus pandemic

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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