Clinical Trial News and Research

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Patients with treatment-resistant depression benefit from ketamine

Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to-date led by researchers from the Icahn School of Medicine at Mount Sinai.

20 May 2013

EndoChoice's new Fuse system improves accuracy of colonoscopy procedure

Although colonoscopy exams prevent many colon cancer deaths and are considered the most sensitive method for detecting colorectal cancers, the procedure is not completely effective in preventing cancer cases. EndoChoice Inc. today unveiled research that shows that its new Fuse system significantly improves the accuracy of this procedure and greatly reduces the number of adenomas missed by colonoscopists.

20 May 2013

Safety and efficacy evaluation methods for medical devices

Medical devices are any medical items that are neither a drug nor a biological product. In light of their different mechanisms, actions and regulatory requirements, medical device trail evaluations are much more complicated than drug trails due to their unique clinical practices.

18 May 2013

A*STAR, Cytos Biotechnology provide update on Phase 1 clinical trial of H1N1 influenza vaccine

Singapore's Agency for Science, Technology and Research and Switzerland's Cytos Biotechnology AG today announced that the first healthy volunteer has been dosed in a Phase 1 clinical trial with their H1N1 influenza vaccine candidate based on Cytos' proprietary bacteriophage Qbeta virus-like particle technology.

17 May 2013

Cedars-Sinai launches new clinical trial to study effects of cabozantinib in prostate cancer patients

Researchers at Cedars-Sinai have launched a new clinical trial to investigate the effects of a cancer-fighting drug therapy that has shown favorable outcomes in patients with advanced metastatic prostate cancer.

17 May 2013

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

Northwest Biotherapeutics, a biotechnology company developing DCVax-L personalized immune therapies for solid tumor cancers, today announced that its Phase III clinical trial with DCVax-L for brain cancer has been initiated at King's College Hospital in the UK.

17 May 2013

InVivo Therapeutics to sponsor Working 2 Walk symposium

InVivo Therapeutics Holdings Corp., a developer of groundbreaking technologies for the treatment of spinal cord injuries and other neurotrauma conditions, today announced that the Company is the Title Sponsor of the 8th annual Working 2 Walk Science & Advocacy Symposium taking place September 27-28, 2013 at the Boston Convention & Exhibit Center in Boston, MA.

16 May 2013

Idelalisib phase 1 clinical trial shows positive results in patients with CLL

A new oral targeted drug, idelalisib (GS-1101), has the potential to stave off the need for additional treatments for relapsed or treatment-resistant chronic lymphocytic leukemia, according to a study led in part by Dana-Farber Cancer Institute investigators.

16 May 2013

Study underscores new paradigm in cancer therapy

In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers.

16 May 2013

Prostate cancer drug Xofigo gets FDA approval

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs.

16 May 2013

Tokai Pharmaceuticals raises $35.5M in Series E financing

Tokai Pharmaceuticals, Inc., a biopharmaceutical company focused on developing new treatments for prostate cancer, today announced that the company raised $35.5 million in a Series E financing based on encouraging clinical progress and investor support for galeterone (TOK-001), Tokai's lead prostate cancer drug candidate.

15 May 2013

UIC's Center for Clinical and Translational Science selects six research projects for new pilot grants

The University of Illinois at Chicago's Center for Clinical and Translational Science has selected six research projects to receive pilot grants in 2013.

15 May 2013

Renaissance in drug development for rare diseases

Once famously described as "orphan diseases, too small to be noticed, too small to be funded" in the Hollywood drama Lorenzo's Oil, rare diseases are getting unprecedented attention today among drug manufacturers, who are ramping up research efforts and marketing new medicines that promise fuller lives for children and other patients with these heartbreaking conditions.

14 May 2013

India's DBT, Bharat Biotech announce positive Phase III clinical trial results of rotavirus vaccine

The Government of India's Department of Biotechnology and Bharat Biotech announced positive results from a Phase III clinical trial of a rotavirus vaccine developed and manufactured in India.

14 May 2013

NCCC doctors find effective drug combination to treat chronic lymphocytic leukemia

Doctors at Dartmouth-Hitchcock's Norris Cotton Cancer Center have found a combination of drugs to potentially treat chronic lymphocytic leukemia more effectively.

14 May 2013

UNM Cancer Center to participate in Phase 3 clinical trial of novel treatment for men with prostate cancer

The University of New Mexico Cancer Center is among a few select institutions nationwide participating in a Phase 3 clinical trial studying a novel treatment for men with newly diagnosed, localized prostate cancer.

13 May 2013

John Theurer to host 9th annual neuro-oncology symposium on May 17

John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 cancer centers, will host its Ninth Annual Neuro-Oncology Symposium on Friday, May 17th from 8:00am-1:00pm. Experts from MD Anderson, Memorial Sloan Kettering Cancer Center, Penn State Milton S. Hershey Medical Center, and the Cleveland Clinic will present advances in multidisciplinary care for cancers of the central nervous system.

10 May 2013

Mouse study shows leukemia halts accumulation of toxic proteins linked to Parkinson's disease

Researchers at Georgetown University Medical Center have used tiny doses of a leukemia drug to halt accumulation of toxic proteins linked to Parkinson's disease in the brains of mice. This finding provides the basis to plan a clinical trial in humans to study the effects.

10 May 2013

Operating without interrupting warfarin treatment during cardiac device surgery reduces hematomas

A new Canadian study shows that operating without interrupting warfarin treatment at the time of cardiac device surgery is safe and markedly reduces the incidence of clinically significant hematomas compared to the current standard of care.

10 May 2013

Severe anorexia nervosa improves with modification of standard goals, treatment methods

A new, multinational randomized clinical trial has found that patients with severe and enduring anorexia nervosa will not only stick with treatments but also make significant improvements with just a slight modification of the standard goals and methods of treatment.

10 May 2013

Clinical Trial News and Research

Patients with treatment-resistant depression benefit from ketamine

EndoChoice's new Fuse system improves accuracy of colonoscopy procedure

Safety and efficacy evaluation methods for medical devices

A*STAR, Cytos Biotechnology provide update on Phase 1 clinical trial of H1N1 influenza vaccine

Cedars-Sinai launches new clinical trial to study effects of cabozantinib in prostate cancer patients

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

InVivo Therapeutics to sponsor Working 2 Walk symposium

Idelalisib phase 1 clinical trial shows positive results in patients with CLL

Study underscores new paradigm in cancer therapy

Prostate cancer drug Xofigo gets FDA approval

Tokai Pharmaceuticals raises $35.5M in Series E financing

UIC's Center for Clinical and Translational Science selects six research projects for new pilot grants

Renaissance in drug development for rare diseases

India's DBT, Bharat Biotech announce positive Phase III clinical trial results of rotavirus vaccine

NCCC doctors find effective drug combination to treat chronic lymphocytic leukemia

UNM Cancer Center to participate in Phase 3 clinical trial of novel treatment for men with prostate cancer

John Theurer to host 9th annual neuro-oncology symposium on May 17

Mouse study shows leukemia halts accumulation of toxic proteins linked to Parkinson's disease

Operating without interrupting warfarin treatment during cardiac device surgery reduces hematomas

Severe anorexia nervosa improves with modification of standard goals, treatment methods

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