Clinical Trial News and Research

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University of Nottingham to study use of tranexamic acid in people with intracerebral haemorrhage

Scientists in Nottingham are leading an international study to investigate the effectiveness of a new treatment on a devastating type of stroke.

19 Mar 2013

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

The following research from Columbia University Medical Center and NewYork-Presbyterian Hospital is being presented at the 65th annual meeting of the American Academy of Neurology, March 16-23, 2013, in San Diego.

18 Mar 2013

Study shows improved detection of dementia paves the way for refined clinical trials testing

A series of studies demonstrate improved detection of the second most common form of dementia, providing diagnostic specificity that clears the way for refined clinical trials testing targeted treatments.

18 Mar 2013

CHOP expert to receive Pediatric Oncology Award from ASCO

The American Society of Clinical Oncology today announced it will confer one of its highest awards on pediatric oncologist Garrett M. Brodeur, M.D., of the Cancer Center at The Children's Hospital of Philadelphia.

16 Mar 2013

Interventional endovascular therapy is safe but does not improve MS outcomes: Study

The first controlled clinical trial to test the safety and efficacy of interventional endovascular therapy on the symptoms and progression of multiple sclerosis has found that the intervention, sometimes called the "liberation treatment," which has attracted intense interest in the global MS community, does not improve patient outcomes. In a few cases, the treatment made symptoms worse.

16 Mar 2013

Diffusion Pharmaceuticals enrolls patients with primary brain cancer in Phase II clinical trial of TSC

Diffusion Pharmaceuticals LLC today announced completion of enrollment in a Phase II clinical trial of trans sodium crocetinate, its lead compound for the treatment of cancer.

15 Mar 2013

Pervasive myths surround clinical trials

A clinical trial evaluates - in humans - a drug, device or mode of therapy for a disease. All therapies put into use in the U.S. go through a rigorous process of testing, culminating in evaluation of the treatment in human research participants. In order to test new treatments, clinical trial investigators at research institutions like UK must recruit participants willing to contribute to science, while often reaping the benefits of advanced treatment for themselves, and gaining access to top clinicians and the latest medical information.

15 Mar 2013

Non-surgical weight loss devices: an interview with Richard Thompson, CEO ReShape Medical

Only a very few percent of patients that qualify for weight loss surgery actually choose to have it. It is a last resort and most patients do not see themselves as ready to give up. On the other hand, diet and exercise rarely work well and patients are looking for some extra help in their quest to lower their weight. A reversible, non-surgical approach has a lot of appeal to these patients.

15 Mar 2013

New approach to reduce gap between Western and traditional medicine

Scientists are reporting an advance toward overcoming a major barrier to tapping the potential of traditional Chinese medicine and India's Ayurvedic medicine in developing new and more effective modern drugs.

15 Mar 2013

Results from GTx's Phase 2 clinical trial of enobosarm published online

GTx, Inc. today announced that the journal, The Lancet Oncology, has published online ahead of its April print edition the results from GTx's randomized, double-blind, placebo-controlled Phase 2 clinical trial of enobosarm to assess its effects on muscle wasting and physical function in patients with cancer.

15 Mar 2013

Phase 1b study of olesoxime initiated in multiple sclerosis (MS) patients

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14 Mar 2013

Synthesis & Solid State Pharmaceutical Centre: an interview with Dr Mary Shire, University of Limerick

This is a new research centre led by the University of Limerick that supports the pharmaceutical sector in Ireland. The centre will carry out research on the key aspects of what it takes to synthesise the pharmaceutically active molecule to isolate a pure material and to formulate this into a medicine.

14 Mar 2013

Specialists offer new technique for nostril reconstruction

The skin cancer growing on Carolyn Bohlmann's nose was not a very aggressive variety. But it was deep and located right on her nostril. The tricky part was not so much removing it - MOHS surgery, the procedure Bohlmann had, is a fairly common outpatient procedure.

14 Mar 2013

Combination of stem cell therapy and physical therapy can reverse effects of spinal cord injury

Walking is the obvious goal for individuals who have a chronic spinal cord injury, but it is not the only one. Regaining sensation and continence control also are important goals that can positively impact an individual's quality of life.

14 Mar 2013

RELAX study finds no beneficial effects of erectile dysfunction drug for diastolic heart failure

Despite high expectations for a commonly used erectile dysfunction drug to treat patients with diastolic heart failure, no beneficial effects were found in a study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

13 Mar 2013

Adult stem cell treatment for diabetic wounds

Pre-clinical research has generated some very promising findings using adult stem cells for the treatment of diabetic wounds. The research carried out by scientists at the National University of Ireland Galway, is published in Diabetes, the official journal of the American Diabetes Association.

13 Mar 2013

Lithera commences LIPO-202 Phase 2b trial for reduction of subcutaneous fat

Lithera, Inc., a clinical stage pharmaceutical company focused on lifestyle and medical indications in aesthetic medicine and ophthalmology, announced today that the first patient has been treated with LIPO-202 (Salmeterol Xinafoate for Injection) in its 500-patient Phase 2b "RESET" trial.

12 Mar 2013

Cangrelor solidly outperforms clopidogrel during percutaneous coronary intervention

The experimental anti-clotting drug cangrelor solidly outperformed commonly used clopidogrel in a large global trial of patients who underwent coronary stent procedures, according to data from the phase III CHAMPION PHOENIX study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

Results from Orion Pharma’s ORM-12741 phase IIa study on AD

A new drug may improve memory problems in people with moderate Alzheimer's disease, according to a phase IIa study released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013. The drug is called ORM-12741.

12 Mar 2013

NIH-sponsored comparative trial evaluates benefits of combination therapy and monotherapy in MS

People with multiple sclerosis (MS) who were treated with combination therapy did not see significant clinical benefit over those treated with single drug therapy, but combination therapy did reduce the development of new lesions, according to an international research team led by The Mount Sinai Medical Center.

12 Mar 2013

Clinical Trial News and Research

University of Nottingham to study use of tranexamic acid in people with intracerebral haemorrhage

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

Study shows improved detection of dementia paves the way for refined clinical trials testing

CHOP expert to receive Pediatric Oncology Award from ASCO

Interventional endovascular therapy is safe but does not improve MS outcomes: Study

Diffusion Pharmaceuticals enrolls patients with primary brain cancer in Phase II clinical trial of TSC

Pervasive myths surround clinical trials

Non-surgical weight loss devices: an interview with Richard Thompson, CEO ReShape Medical

New approach to reduce gap between Western and traditional medicine

Results from GTx's Phase 2 clinical trial of enobosarm published online

Phase 1b study of olesoxime initiated in multiple sclerosis (MS) patients

Synthesis & Solid State Pharmaceutical Centre: an interview with Dr Mary Shire, University of Limerick

Specialists offer new technique for nostril reconstruction

Combination of stem cell therapy and physical therapy can reverse effects of spinal cord injury

RELAX study finds no beneficial effects of erectile dysfunction drug for diastolic heart failure

Adult stem cell treatment for diabetic wounds

Lithera commences LIPO-202 Phase 2b trial for reduction of subcutaneous fat

Cangrelor solidly outperforms clopidogrel during percutaneous coronary intervention

Results from Orion Pharma’s ORM-12741 phase IIa study on AD

NIH-sponsored comparative trial evaluates benefits of combination therapy and monotherapy in MS

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