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Research reveals inaccuracies in common gene therapy measurement technique

In a finding with implications for one of the most promising cutting-edge medical treatments, researchers evaluated several measurement techniques commonly used in gene therapy.

13 Jan 2025

Researchers uncover role of perivascular cells in blood vessel dysfunction

Researchers at Oregon Health & Science University have uncovered how specialized cells surrounding small blood vessels, known as perivascular cells, contribute to blood vessel dysfunction in chronic diseases such as cancer, diabetes and fibrosis.

13 Jan 2025

Intermittent fasting shows promise in managing obesity and cardiovascular health

A team of scientists led by the University of Granada (UGR), the Public University of Navarra (UPNA) and the CIBER has shown that intermittent fasting (reducing the number of hours of intake and extending the hours of fasting each day) is an effective method for losing weight and improves cardiovascular health in people with obesity problems.

8 Jan 2025

Single-dose malaria vaccine offers unprecedented 90% protection

Results from the malaria vaccine trial indicate that GA2 immunization provides significant protection, paving the way for more effective vaccination strategies.

8 Jan 2025

H5N1 bird flu spillover to horses, raises fears of new viral strains

Researchers report the first confirmed cases of H5N1 bird flu in horses, highlighting their role as potential reservoirs for viral reassortment. This groundbreaking study urges increased surveillance to prevent novel influenza epidemics.

5 Jan 2025

Researchers grow tumor organoids from blood to tackle breast cancer metastasis

Tumor cells circulating in the blood are the "germ cells" of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult.

3 Jan 2025

CDC study highlights growing tularemia threat in central U.S.

Tularemia cases in the U.S. rose by 56% from 2011 to 2022, with central states and American Indian communities most affected, highlighting diagnostic advancements and health disparities.

2 Jan 2025

AI-based models can outperform human experts at identifying ovarian cancer

A new international study led by researchers at Karolinska Institutet in Sweden shows that AI-based models can outperform human experts at identifying ovarian cancer in ultrasound images.

2 Jan 2025

New SIMPL2 platform revolutionizes the study of protein-protein interactions

A team led by researchers at the University of Toronto has created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while improving measurement accuracy.

23 Dec 2024

Breakthrough microchip technology enables multi-disease detection

In a world grappling with a multitude of health threats - ranging from fast-spreading viruses to chronic diseases and drug-resistant bacteria - the need for quick, reliable, and easy-to-use home diagnostic tests has never been greater. Imagine a future where these tests can be done anywhere, by anyone, using a device as small and portable as your smartwatch.

16 Dec 2024

Gut microbiome during acute infection predicts risk of long COVID

The study identifies gut microbiome signatures during acute SARS-CoV-2 infection as predictors of long COVID, enhancing understanding of symptom variability.

16 Dec 2024

Skin as an immune hero: Fighting infections with self-made antibodies

Researchers uncover how the skin autonomously produces antibodies through specialized immune structures, maintaining microbial balance and preventing infections.

12 Dec 2024

Elevated PGE2 levels drive age-related skin changes and cancer risk

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21 on November 18, 2024, entitled, "Prostaglandin E2 regulates senescence and post-senescence neoplastic escape in primary human keratinocytes."

11 Dec 2024

Bovine H5N1 influenza shows potential for human adaptation through key mutations

Recent study reveals H5N1 mutations enhancing human receptor binding, highlighting pandemic risks and the need for vigilant surveillance of influenza strains.

9 Dec 2024

Researchers discover new receptor in pain signaling pathway

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a study published in the Journal of Clinical Investigation.

6 Dec 2024

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

Study highlights the safety and early bactericidal activity of quabodepistat when combined with delamanid, bedaquiline, or both, offering potential for shorter and more tolerable tuberculosis treatment regimens.

1 Dec 2024

Late-liver-stage malaria vaccine delivers 89% protection and boosts cellular immunity

Genetically attenuated malaria parasites with extended liver-stage arrest (GA2) showed 89% protection in a clinical trial, surpassing earlier vaccine candidates and highlighting the potential of cellular immunity.

26 Nov 2024

How gut bacteria regulate stress and sleep cycles

This study reveals that gut microbiota, particularly Lactobacillus species, regulate the daily rhythm of stress hormones like corticosterone, influencing stress responses and brain function at different times of the day. Disruptions in gut bacteria lead to altered stress responses and increased susceptibility to disorders like depression.

10 Nov 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

Scientists develop synthetic genes that can build intracellular structures

Researchers from the UCLA Samueli School of Engineering and the University of Rome Tor Vergata in Italy have developed synthetic genes that function like the genes in living cells.

4 Nov 2024