Exosome News and Research

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New strategy shows promises for treating RNA-repeat expansion disorders

A new strategy for treating a variety of diseases known as RNA-repeat expansion disorders, which affect millions of people, has shown promise in proof-of-principle tests conducted by scientists at Scripps Research.

8 Nov 2020

Study may pave way for more effective treatment for Hepatitis C

Virologists at Institut national de la recherche scientifique (INRS) have identified a critical role played by a cellular protein in the progression of Hepatitis C virus infection, paving the way for more effective treatment.

22 Oct 2020

A new therapeutic approach for Epstein-Barr virus-associated tumors

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that exosomes derived from Vδ2-T cells (Vδ2-T-Exos) can effectively control Epstein-Barr virus-associated tumours and induce T-cell anti-tumour immunity.

12 Oct 2020

Exosomes yield regenerative benefits equivalent to hiPSC-CCs, shows study

Science has long known that recovery from experimental heart attacks is improved by injection of a mixture of heart muscle cells, endothelial cells and smooth muscle cells, yet results have been limited by poor engraftment and retention, and researchers worry about potential tumorigenesis and heart arrhythmia.

30 Sep 2020

Researchers develop new strategy to mimic heart-regenerating effects of cardiac cell transplants

Ling Gao and colleagues have developed a strategy that uses exosomes - tiny membrane-bound sacs secreted by cells - to mimic the heart-regenerating effects of cardiac cell transplants, while potentially avoiding risks associated with whole-cell transplants.

17 Sep 2020

Antiviral effects of honeysuckle decoction affected in SIDT1poly population

Previously, Chen-Yu Zhang's group have identified SID1 transmembrane family member 1 (SIDT1) as a critical membrane protein mediating dietary miRNAs absorption, which is abolished in SIDT1 deficient mice.

11 Sep 2020

Exosomes: The cancer cell communication mechanism

Professor Deborah Goberdhan speaks to News-Medical about her team's latest research into cancer cells, and the mechanisms they use to communicate.

26 Aug 2020

Faulty RNA quality control system leads to haywire production of toxic proteins in FTLD/ALS

Researchers at Osaka University identify vicious cycle involving RNA exosome that accelerates disease progression in FTLD/ALS

24 Aug 2020

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

17 Aug 2020

Fat cell hormone enhances therapeutic potential of MSC therapy

Mesenchymal stem cells (MSCs) have the potential to differentiate into a range of different cell types, including bone, fat, and muscle cells.

12 Jul 2020

Expansion stress promotes aggressive tumor cell growth in breast cancer

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

9 Jul 2020

New technology detects breast cancer using tears

Kobe University and System Instruments Co., Ltd. researchers have developed TearExo; new technology to detect breast cancer using the exosomes found in tears as biomarkers. Exosomes are a subtype of extracellular vesicles.

19 Jun 2020

GMU researchers studying effect of cannabidiol on exosome release

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally driven HIV pathenogenesis in the central nervous system.

5 Jun 2020

New paper-based technology could lead to earlier detection of cancer

Washington State University researchers have developed a technology that is more than 30 times more sensitive than current lab-based tests in finding early stage cancer biomarkers in blood.

4 Jun 2020

Baylor College of Medicine and UH team up for new research collaborations

Baylor College of Medicine and the University of Houston are teaming up for new research collaborations.

10 Mar 2020

Exosome treatment promotes remarkable stroke recovery in swine models

It's been almost a quarter century since the first drug was approved for stroke. But what's even more striking is that only a single drug remains approved today.

14 Jan 2020

New gene therapy has potential to reverse disease processes

Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.

17 Dec 2019

Detection of mouth, throat cancer through saliva testing could become reality

Cancer of the throat and mouth (oropharyngeal cancers, OPC) are common, and are increasing in incidence especially among younger people. However, these are difficult to diagnose as they are not seen either by the patient or during routine medical examinations.

15 Dec 2019

New technique may lead to earlier and easier detection of mouth and throat cancer

Unfortunately, cancers that occur in the back of the mouth and upper throat are often not diagnosed until they become advanced, partly because their location makes them difficult to see during routine clinical exams.

13 Dec 2019

Research could pave way for regenerative TBI-IV therapy

A team of researchers from the University of Georgia's Regenerative Bioscience Center has found that neural exosomes- "cargo" molecules within the nervous system that carry messages to the brain- can minimize or even avert progression of traumatic brain injury when used as part of a new cell-to-cell messaging technology.

12 Dec 2019