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Improving logical reasoning in large language models for medical use

Large language models (LLMs) can store and recall vast quantities of medical information, but their ability to process this information in rational ways remains variable.

17 Oct 2025

Mass General Brigham study shows US obesity could jump from 40% to 70%

The prevalence of obesity in the United States could rise sharply under a new definition of obesity released earlier this year by the Lancet Diabetes and Endocrinology Commission.

16 Oct 2025

HEPA purifiers do not fully reduce classroom viral exposure

In a secondary analysis of a study of 200 classrooms, Mass General Brigham researchers found respiratory viral exposures were still high in those with HEPA purifiers, suggesting additional interventions are needed.

10 Oct 2025

Repeated sampling offers insight into glioblastoma therapy response

A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect when a cancer treatment is activating the immune system in recurrent glioblastoma (GBM), even when traditional imaging measures cannot.

8 Oct 2025

AI must optimize home care, continuity, and early detection for older adults

HealthFORCE, a national alliance of leaders dedicated to addressing the root causes of America's healthcare workforce crisis, along with the American Academy of Physician Associates (AAPA) and West Health, today released "Aging Well with AI: Empowering Care through Innovation," the first in a two-part white paper series exploring how artificial intelligence (AI) can strengthen the U.S. healthcare workforce and improve access to care.

7 Oct 2025

TBI-associated dementia risk emphasizes need for targeted fall prevention programs

Traumatic brain injuries (TBI) in older adults are associated with new cases of dementia, use of home care services, and admission to long-term care, according to new research published in CMAJ (Canadian Medical Association Journal)

6 Oct 2025

Study finds limited value of CGM data for non-diabetic individuals

Continuous glucose monitors (CGMs) are wearable technologies that track blood sugar in real time and help patients with type 2 diabetes improve blood sugar control.

2 Oct 2025

Wearable device can help lower relapse risk in early addiction recovery

A new study by investigators from Mass General Brigham shows that a non-drug, wearable device can help people with substance use disorders (SUD) manage stress, reduce cravings, and lower their risk of relapse in real time.

2 Oct 2025

NIH funds multi-state pilot for genome sequencing in newborn screening

Mass General Brigham and Ariadne Labs, alongside Boston Children's Hospital, Albert Einstein College of Medicine, the Association of Public Health Laboratories (APHL), Case Western Reserve University, Baylor College of Medicine, and sequencing partners GeneDx and Illumina, today announced the launch of BEACONS (Building Evidence and Collaboration for GenOmics in Nationwide Newborn Screening), the nation's first multi-state genomic newborn screening initiative.

2 Oct 2025

Respite services significantly increase home deaths for palliative care patients

Access to respite services for family caregivers increases a palliative care patient's probability of dying at home almost threefold, according to a McGill University-led study.

23 Sep 2025

Study sheds light on how inadequate sleep in teens can contribute to cycles of violence

Mass General Brigham study also finds link to violent behaviors such as carrying a weapon, highlighting the vicious cycle between lack of sleep and violence.

22 Sep 2025

Cocoa extract supplements linked to reduced inflammation in older adults

Could cocoa extract supplements rich in cocoa flavanols reduce inflammation and, in turn, prevent age-related chronic diseases? In a new study from the COcoa Supplement and Multivitamin Outcomes Study (COSMOS), investigators from Mass General Brigham and their colleagues looked at changes in five age-related markers of inflammation among participants who received daily cocoa supplements over several years.

17 Sep 2025

GLP-1 drugs may offer cost-effective treatment for people with knee osteoarthritis and obesity

A new study led by investigators at Mass General Brigham finds that adding novel weight loss GLP-1 drugs semaglutide and tirzepatide to usual care represents a cost-effective treatment strategy for people with knee osteoarthritis and obesity, with tirzepatide providing greater health benefits at lower cost compared to semaglutide.

16 Sep 2025

AI-powered hydrogel dressings transform chronic wound care

As chronic wounds such as diabetic ulcers, pressure ulcers, and articular wounds continue to challenge global healthcare systems, a team of researchers from China has introduced a promising innovation: AI-integrated conductive hydrogel dressings for intelligent wound monitoring and healing.

12 Sep 2025

CRISPR-based therapeutic approach designed to treat fatal pediatric disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

11 Sep 2025

HPV-DeepSeek shows promise for early detection of head and neck cancer

Human papilloma virus (HPV) causes around 70% of head and neck cancers in the United States, making it the most common cancer caused by the virus, with rates increasing each year.

9 Sep 2025

Shifts in meal timing predict health and longevity in older adults

As we age, what and how much we eat tends to change. However, how meal timing relates to our health remains less understood. Researchers at Mass General Brigham and their collaborators studied changes to meal timing in older adults and discovered people experience gradual shifts in when they eat meals as they age.

4 Sep 2025

Inflammation marker can help identify heart risk in women without traditional factors

Cardiologists have long known that up to half of all heart attacks and strokes occur among apparently healthy individuals who do not smoke and do not have high blood pressure, high cholesterol, or diabetes, the "standard modifiable risk factors" which doctors often call "SMuRFs."

29 Aug 2025

No Surprises Act significantly reduces out of pocket healthcare costs

Investigators at Mass General Brigham and the Richard A. and Susan F. Smith Center for Outcomes Research at Beth Israel Deaconess Medical Center have uncovered how patients' healthcare spending has changed following the implementation of the No Surprises Act in 2022, a bipartisan law prohibiting unexpected or "surprise" bills after patients receive out-of-network medical care.

28 Aug 2025

Study identifies key metric for safe blood brain barrier opening in glioblastoma patients

Researchers found that acoustic emission dose-an acoustic signal from microbubbles-could predict how to adjust ultrasound power and open the blood brain barrier for delivering drugs in patients with glioblastoma.

25 Aug 2025