Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Surgeons’ opioid-prescribing habits hard to kick

As opioid addiction and deadly overdoses escalated into an epidemic across the U.S., thousands of surgeons continued to hand out far more pills than needed for postoperative pain relief, according to a KHN-Johns Hopkins analysis of Medicare data.

21 Jun 2019

Research sheds light on ‘black box’ of inpatient opioid use

People who receive opioids for the first time while hospitalized have double the risk of continuing to receive opioids for months after discharge compared with their hospitalized peers who are not given opioids, according to research led by scientists at the University of Pittsburgh Graduate School of Public Health.

18 Jun 2019

Cedars-Sinai expert urges physicians and patients to manage pain without addictive pills

As the opioid epidemic continues to claim lives and shatter families across the nation, a Cedars-Sinai expert is urging physicians and patients to try managing pain without the addictive pills.

17 Jun 2019

Lawmakers push to stop surprise ER billing

California has some of the nation's strongest protections against surprise medical bills. But many Californians still get slammed with huge out-of-network charges.

29 May 2019

Filled opioid prescriptions are relatively rare in Medicaid-enrolled children, finds study

A new study describes trends in filled opioid prescriptions by patient and clinical characteristics for Medicaid-enrolled children.

27 Apr 2019

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Exposure to potentially harmful chemicals is a reality of life. Our ancestors, faced with naturally occurring toxins, evolved mechanisms to detoxify and expel damaging substances.

15 Mar 2019

Proving the efficacy of traditional Chinese medicine

Using GC-MS, scientists have uncovered the anti-pyretic mechanisms of Jinxin, a traditional Chinese medicine typically prescribed for fever.

11 Mar 2019

New guidelines on clinical use of life-saving antibiotics

An international panel of the foremost researchers on infectious disease and antimicrobials has formed new guidelines on the use of polymyxins, a class of antibiotics employed as a last resort to treat deadly, drug-resistant bacteria.

11 Mar 2019

Machine learning tool could prevent unnecessary treatments for kids with arthritis

Arthritis is not just an ailment of old age--it can affect children too, causing lifelong pain and disability in its most severe forms. Fortunately, some kids grow out of it. Knowing which patients will develop milder forms of disease could spare them unnecessary treatment and potential medication side effects but currently doctors have no way of predicting disease course or severity.

27 Feb 2019

Study finds drug interactions in ER's are common but could be prevented

In a recent Rutgers study, 38 percent of patients discharged from the emergency department had at least one drug interaction resulting from a newly prescribed medicine.

26 Feb 2019

Big-data analysis finds new link between popular arthritis drug and heart valve calcification

A well-known, four-year study found popular arthritis drug Celebrex no more dangerous for the heart than older drugs in its same classification - commonly called NSAIDs.

23 Feb 2019

Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs

Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide. They are used above all for the treatment of inflammatory reactions. However, in spite of their indisputable effectiveness and frequent use, we do not yet fully understand the underlying mechanisms of these drugs.

23 Feb 2019

The American Heart Association issues new reference toolkit for healthcare providers

With nearly half of American adults having elevated blood pressure, it’s important for everyone to understand that some common habits may affect blood pressure, making the condition more difficult to control.

21 Feb 2019

Research finds steep rise in self-poisonings among young people

Self-harm from self-poisoning in children and adolescents is not only increasing but starting at a younger age, finds new research by University of Sydney and the NSW Poisons Information Centre.

20 Feb 2019

Patients taking anti-depressants more likely to develop gastrointestinal bleeding

Patients taking anti-depressant medications classified as selective serotonin reuptake inhibitors are 40 percent more likely to develop severe gastrointestinal bleeding, particularly when they also use common over-the-counter pain relievers, according to a research review in the Journal of the American Osteopathic Association.

31 Jan 2019

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found.

25 Jan 2019

Opioid drugs often overprescribed to children for pain relief, say CHOP surgeons

Opioid drugs prescribed to children for pain relief after a typical pediatric orthopaedic procedure may be significantly overprescribed, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

17 Jan 2019

Insured but still in debt: 5 jobs pulling in $100k a year no match for medical bills

Robert and Tiffany Cano of San Tan Valley, Ariz., have a new marriage, a new house and a 10-month-old son, Brody, who is delighted by his ability to blow raspberries.

28 Dec 2018

Virginia Tech and UC San Diego researchers team up to develop nonopioid drug for chronic pain

Researchers from the Virginia Tech School of Neuroscience are teaming with the University of California San Diego and the U.S. National Institutes of Health to develop a drug -- now in its earliest stages -- that can treat certain types of chronic pain without the addictive consequences of opioids.

12 Dec 2018

Inhibition of prostaglandin E2 enhances ability to combat infectious colitis

The treatment of intestinal infections caused by some strains of the bacterium Escherichia coli, present in unsanitized or contaminated foods, may have a new ally.

15 Nov 2018