Liver Transplantation News and Research

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Researchers uncover new mechanism that plays key role in the progression of alcohol-related liver disease

Alcohol-related liver disease is among the most common causes of morbidity and mortality worldwide. Due to an incomplete understanding of the factors contributing to disease development, liver transplantation is still the only available cure.

24 Jan 2023

Protein heat shock transcription factor 1 may be a viable therapeutic target for hepatoblastoma

Although rare compared to adult liver cancers, hepatoblastoma is the most common pediatric liver malignancy, and its incidence is increasing.

16 Jan 2023

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

HKUMed researchers at AIDS Institute, Department of Microbiology and Department of Surgery, School of Clinical Medicine, and School of Biomedical Sciences discover the role of an isoformic programmed cell death protein 1 (PD-1), namely Δ42PD-1, in suppressing the function of killer T cells, which is a type of immune cells essential for killing cancer cells among hepatocellular carcinoma (HCC) patients.

15 Dec 2022

Livers have a cumulative age of at least 100 years, researchers find

There is a small, but growing, subset of livers that have been transplanted and have a cumulative age of more than 100 years, according to researchers from University of Texas (UT) Southwestern Medical Center, Dallas, and TransMedics, Andover, Massachusetts.

17 Oct 2022

Study offers support for increasing the use of living donor liver transplantation in Western countries

Demand for donor livers for transplant patients outstrips supply with over 15% of waitlist patients dying after a year.

26 Sep 2022

New board members bring significant leadership experience in the biotech sector

Aspect Biosystems, a biotechnology company pioneering the development of bioprinted tissue therapeutics to transform how we treat disease, is pleased to announce the appointment of three new members to its Board of Directors: Dr. Nancy Krieger, Dr. Don Haut, and Dr. Devyn Smith.

From Aspect Biosystems 22 Sep 2022

A triad of obesity, heavy alcohol use, and coagulopathy predicts return to OR after liver transplant

Liver transplant surgery is a vital and life-saving procedure, but it also is associated with a high rate of postoperative complications.

26 Aug 2022

Transplant remains the standard of care for liver cancer patients, regardless of age

Physicians and researchers from UK HealthCare's Transplant Center and the University of Kentucky Markey Cancer Center conducted a study of patients over the age of 70 with a type of liver cancer called hepatocellular carcinoma (HCC) and how the outcomes of ablative treatments compare to liver transplants.

28 Jul 2022

Researchers find adeno-associated virus 2 infection in children with hepatitis of unknown etiology

Researchers investigated the cases of severe hepatitis of unknown etiology in young children who presented to the hospital between 14 March and 4 April 2022 in Scotland.

28 Jul 2022

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease.

21 Jun 2022

Co-circulation of adenovirus 40/41 and SARS-CoV-2 and emergence of hepatitis cases in children

In a recent study posted to the medRxiv* pre-print server, KU Leuven researchers investigated whether there was an association between the intensity of the co-circulation of adenovirus (AdV) 40/41 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the number of hepatitis cases of unknown origin emerging in Belgium.

12 Jun 2022

Liver4Life research team treated damaged liver in a machine and then implanted the recovered organ

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.

31 May 2022

Study: Liver transplants from drug overdose donors increased in the pandemic's first year

Liver transplants from drug overdose donors rose significantly in the pandemic's first year, helping keep the number of liver transplants in the U.S. stable despite COVID-19 disruptions, according to a study to be presented at Digestive Disease Week 2022.

23 May 2022

Study outlines risk factors for autoimmune hepatitis after liver transplant

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation.

20 May 2022

Transformational $104 million gift will help VCU to expand treatment options for liver diseases

Virginia Commonwealth University will radically expand treatment options for liver and liver-related metabolic diseases thanks to a historic, transformational $104 million gift from Richard Todd Stravitz, M.D., and his family's Barbara Brunckhorst Foundation.

15 Feb 2022

Study finds 50% increase in hospitalizations for alcoholic hepatitis in early months of the pandemic

In new research published in Liver International, researchers at Henry Ford Health System have found that people hospitalized for alcoholic hepatitis – a life threatening liver disease fueled by alcohol use – increased a staggering 50 percent in the early months of the COVID-19 pandemic.

9 Feb 2022

Liver Transplantation News and Research

Researchers uncover new mechanism that plays key role in the progression of alcohol-related liver disease

Protein heat shock transcription factor 1 may be a viable therapeutic target for hepatoblastoma

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

Livers have a cumulative age of at least 100 years, researchers find

Study offers support for increasing the use of living donor liver transplantation in Western countries

New board members bring significant leadership experience in the biotech sector

A triad of obesity, heavy alcohol use, and coagulopathy predicts return to OR after liver transplant

Transplant remains the standard of care for liver cancer patients, regardless of age

Researchers find adeno-associated virus 2 infection in children with hepatitis of unknown etiology

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

Co-circulation of adenovirus 40/41 and SARS-CoV-2 and emergence of hepatitis cases in children

Liver4Life research team treated damaged liver in a machine and then implanted the recovered organ

Study: Liver transplants from drug overdose donors increased in the pandemic's first year

Study outlines risk factors for autoimmune hepatitis after liver transplant

Transformational $104 million gift will help VCU to expand treatment options for liver diseases

Study finds 50% increase in hospitalizations for alcoholic hepatitis in early months of the pandemic

Two-step strategy can help determine the risk of liver cancer after HCV cure

Scientific review highlights the impact of coffee on digestive organs

New pathways responsible for hepatocellular carcinoma identified

ASTRO provides new guidance on the use of external beam radiation therapy for primary liver cancers

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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