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New non-invasive method boosts the brain's natural waste drainage system

Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain's natural waste drainage system-a discovery that could open new avenues for tackling age-related neurological disorders.

4 Jun 2025

First-in-class antibody-drug conjugate shows high response rates in rare blood cancer trial

The first-in-class antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) demonstrated promising efficacy and high response rates for patients with blastic plasmacytoid dendric cell neoplasm (BPDCN), according to data from a Phase I/II study led by researchers from The University of Texas MD Anderson Cancer Center.

2 Jun 2025

Adding immunotherapy to chemotherapy after surgery improves survival in colon cancer

Colon cancer is the third most prevalent form of cancer in the U.S., and while screening has helped detect and prevent colon cancer from spreading, major advancements in treating colon cancer have lagged.

1 Jun 2025

Scientists uncover how a single gene shaped the course of plague pandemic

Scientists have documented the way a single gene in the bacterium that causes bubonic plague, Yersinia pestis, allowed it to survive hundreds of years by adjusting its virulence and the length of time it took to kill its victims, but these forms of plague ultimately died out.

1 Jun 2025

Genetic evolution of plague bacterium may have prolonged historic pandemics

Scientists at the Institut Pasteur and McMaster University have discovered that the evolution of a gene in the bacterium that causes bubonic plague, Yersinia pestis, may have prolonged the duration of two major pandemics.

29 May 2025

Scientists discover how EBV-infected immune cells migrate and invade the brain

Many people are infected with the Epstein-Barr virus (EBV), and most are unaware of it. However, EBV can sometimes cause cancer, and this pathogen also appears to play an important role in multiple sclerosis and other autoimmune diseases.

19 May 2025

Researchers identify key cells behind peanut allergy prevention

A decade ago, a clinical trial in the U.K. famously showed that children who were exposed to peanuts in the early months of life had reduced risk of developing a peanut allergy compared with children who avoided peanuts.

15 May 2025

Nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, study finds

Most vaccines — and boosters — are injected directly into muscle tissue, usually in the upper arm, to kickstart the body's immune system in the fight against disease.

13 May 2025

Scientists enhance T cell immunity for more durable vaccines

WEHI scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines for viruses and enhanced cancer therapies.

7 May 2025

Early detection of stomach cancer shows major progress

Stomach cancers are increasingly being diagnosed at less advanced, more treatable stages - a shift that marks major progress in detecting one of the deadliest forms of cancer, according to a study to be presented today at Digestive Disease Week 2025.

5 May 2025

AI tools improve detection of key immune structures in melanoma

Researchers from the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) have applied AI-driven processes for detecting tertiary lymphoid structures (TLS) in thousands of digital images of melanoma tumor tissue, significantly enhancing TLS identification and survival predictions for operable stage III/IV patients.

24 Apr 2025

New subtype of Castleman disease identified to improve diagnosis and treatment

A newly identified subtype of Castleman disease will help diagnose and properly treat thousands of patients who have been caught between existing classification systems, marking the first major discovery of its kind in 45 years.

22 Apr 2025

Africa CDC and WHO strengthen mpox response with updated strategy

Africa CDC and WHO have updated their joint Continental Response Plan for the mpox emergency as the disease continues to affect new areas.

18 Apr 2025

Blood test for tumor DNA may predict melanoma recurrence

Monitoring blood levels of DNA fragments shed by dying tumor cells may accurately predict skin cancer recurrence, a new study shows.

15 Apr 2025

Immune system selects the best T cells for targeted defense

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and proliferate during a viral infection.

10 Apr 2025

Powerful new tool promises major advances in cancer treatment

New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery.

8 Apr 2025

New quantum technology set to revolutionize gastrointestinal cancer detection and treatment

New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery.

7 Apr 2025

New trial aims to make rectal cancer more responsive to radiation

City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, has opened a phase 1 trial seeking to one day transform rectal cancer from a mostly radiation-resistant disease to one that can be cured using radiation and chemotherapy.

25 Mar 2025

Targeting brain’s waste removal system may help combat cognitive decline

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease, among others.

21 Mar 2025

Research findings solve the paradox of how the immune system balances speed and precision

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted to keep different pathogens in check.

19 Mar 2025