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New DNA-based vaccine scaffolds boost targeted immune responses to HIV

One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics a virus.

6 Feb 2026

Therapeutic potential of engineered extracellular vesicles in osteoarthritis

Announcing a new article publication for BIO Integration journal. Extracellular vesicles (EVs) are membrane-bound nanoparticles secreted by cells and have emerged as promising therapeutic agents for osteoarthritis (OA).

4 Feb 2026

ERC Proof of Concept grant supports promising CRISPR-based cancer treatment research

Microbiologist John van der Oost of Wageningen University & Research (WUR) has received an ERC Proof of Concept grant to further develop a promising CRISPR-based approach to cancer treatment. With funding of €150,000, he and researcher Christian Südfeld will spend the next eighteen months working on a method to kill cancer cells from within, while sparing healthy cells as much as possible.

30 Jan 2026

Repeated exposure to aged vape plumes could negatively impact lung health

Electronic cigarettes - or vapes - can release puffs of vapor in aromatic clouds. The health risks of breathing in this secondhand or passive vapor aren't fully understood.

30 Jan 2026

Light-driven nanoparticles to target tumors

Researchers at NYU Abu Dhabi have developed a new light-based nanotechnology that could improve how certain cancers are detected and treated, offering a more precise and potentially less harmful alternative to chemotherapy, radiation, and surgery.

30 Jan 2026

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Gene-editing tools like CRISPR have unlocked new treatments for previously uncurable diseases. Now, researchers at the University of British Columbia are extending those possibilities to the skin for the first time.

27 Jan 2026

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

Metastatic urothelial carcinoma has a poor prognosis: ~50% of muscle-invasive bladder cancer progresses to metastasis, and the 5-year survival for advanced/metastatic disease is <10%.

24 Jan 2026

Targeted uterine mRNA treatment boosts fertility outcomes in mice

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine - which designs nanotechnology-based platforms for clinical translation across specialties - developed a strategy for delivering therapeutic messenger RNA (mRNA) to the inner lining of the uterus (endometrium) in mice via modified lipid nanoparticles (LNPs), which are small capsules made of fatty molecules.

22 Jan 2026

Hybrid polymer nanocarriers enable efficient inhaled mRNA vaccine delivery to the lungs

Novel hybrid polymer nanocarriers enable effective vaccine delivery in the lungs and the targeted activation of immune cells.

16 Jan 2026

Targeting microRNA communication reverses pancreatic cancer's immune suppression

In a unique finding, researchers at Georgetown's Lombardi Comprehensive Cancer Center discovered that when pancreatic cancer cells send out tiny particles that are packed with certain microRNA molecules, nearby immune cells called macrophages are reprogrammed to help the tumor grow instead of engaging in their regular role of fighting the tumor.

16 Jan 2026

Water dispensers may contain more bacteria than tap water

A review reveals that water dispensers may harbor microbial contamination, challenging their safety compared to tap water and highlighting maintenance needs.

16 Jan 2026

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

Nitin Joshi, PhD, and Jingjing Gao, PhD, of the Department of Anesthesiology at Mass General Brigham, are the co-senior authors of a paper published in Nature Nanotechnology, "A disease-severity-responsive nanoparticle enables potent ghrelin mRNA therapy in osteoarthritis." Mahima Dewani, PhD, is the lead author of this study.

14 Jan 2026

Researchers identify possible target for new therapies against periodontitis aggravated by smoking

Smoking tobacco is known to worsen symptoms of periodontitis and reduce responsiveness to treatment. Using high-resolution spatial transcriptomics, researchers identified differences between smokers and non-smokers in the expression of genes that weaken gum epithelial integrity and cause bone damage through inflammation.

12 Jan 2026

Cornell-developed nanoparticles improve cancer immunotherapy effectiveness

A class of ultrasmall fluorescent core-shell silica nanoparticles developed at Cornell is showing an unexpected ability to rally the immune system against melanoma and dramatically improve the effectiveness of cancer immunotherapy, according to a new study led by Weill Cornell Medicine and Cornell Engineering researchers.

7 Jan 2026

AI-designed molecular sensors could enable early detection of cancer

Detecting cancer in the earliest stages could dramatically reduce cancer deaths because cancers are usually easier to treat when caught early.

6 Jan 2026

UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

Accelerating advancements in cancer prevention and cures, Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, has received a $900,000 grant from the Cancer Prevention and Research Institute of Texas to develop stronger and more targeted anti-tumor therapy for pancreatic and lung cancer.

6 Jan 2026

New therapeutic approach converts immune cells inside tumors into anticancer cell therapies

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable to perform their roles properly due to suppression by the tumor.

2 Jan 2026

Compact Raman imaging system detects tumors with high sensitivity

Researchers have developed a new compact Raman imaging system that is sensitive enough to differentiate between tumor and normal tissue.

18 Dec 2025

New nanoparticle vaccines show promise against multiple deadly filoviruses

Filoviruses get their name from the Latin word "filum," meaning thread-a reference to their long, filamentous shape. This virus family contains some of the most dangerous pathogens known to science, including Ebola, Sudan, Bundibugyo and Marburg viruses.

18 Dec 2025

Novel mRNA therapy rejuvenates immune function in aging mice

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that this is possible with an innovative approach.

17 Dec 2025

Nanoparticles News and Research

New DNA-based vaccine scaffolds boost targeted immune responses to HIV

Therapeutic potential of engineered extracellular vesicles in osteoarthritis

ERC Proof of Concept grant supports promising CRISPR-based cancer treatment research

Repeated exposure to aged vape plumes could negatively impact lung health

Light-driven nanoparticles to target tumors

First topical CRISPR gene therapy corrects disease-causing mutations in human skin

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

Targeted uterine mRNA treatment boosts fertility outcomes in mice

Hybrid polymer nanocarriers enable efficient inhaled mRNA vaccine delivery to the lungs

Targeting microRNA communication reverses pancreatic cancer's immune suppression

Water dispensers may contain more bacteria than tap water

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

Researchers identify possible target for new therapies against periodontitis aggravated by smoking

Cornell-developed nanoparticles improve cancer immunotherapy effectiveness

AI-designed molecular sensors could enable early detection of cancer

UH pharmacology professor wins $900,000 grant to develop a dual-function nanodrug for cancer

New therapeutic approach converts immune cells inside tumors into anticancer cell therapies

Compact Raman imaging system detects tumors with high sensitivity

New nanoparticle vaccines show promise against multiple deadly filoviruses

Novel mRNA therapy rejuvenates immune function in aging mice

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