Nucleic Acid News and Research

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Breakthrough in understanding formaldehyde toxicity during development and aging

AMeD syndrome is a severe genetic condition found in children that present with accelerated aging, global developmental delay and bone marrow failure, among others, progressing to Myelodysplastic Syndrome and Acute Myeloid Leukaemia.

13 Sep 2024

Severe illness odds higher in COVID-19 vs other illnesses

Study found that COVID-19 cases were more likely to experience severe illness and persistent symptoms compared to non-COVID-19 respiratory illnesses, with age, preexisting conditions, and chronic respiratory disease increasing the risk of post-acute COVID-19 syndrome (PACS).

10 Sep 2024

NIAID awards grants for 10 projects to improve diagnostic tools for syphilis

The National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) has awarded grants for 10 projects to improve diagnostic tools for congenital and adult syphilis - conditions currently diagnosed with a sequence of tests, each with limited precision.

3 Sep 2024

Nucleic acids in food show potential to inhibit cancer cell growth

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit the growth of cancer cells, according to findings published in PLOS ONE by Osaka Metropolitan University Associate Professor Akiko Kojima-Yuasa of the Graduate School of Human Life and Ecology and colleagues.

29 Aug 2024

New technique enhances study of complex biological processes at the molecular level

A team of researchers led by Professor Sebastian Deindl at Uppsala University has developed a pioneering method that vastly improves the ability to observe and analyze complex biological processes at the single-molecule level.

23 Aug 2024

Researchers reveal why a diet rich in magnesium is so important for your health

Researchers examined whether magnesium deficiency in the healthy middle-aged Australian population was independently or in combination with increased homocysteine levels associated with in vivo DNA damage.

15 Aug 2024

New nanosensing technique enhances quality control for gene therapy vectors

Over the past few decades, there has been remarkable progress in genetic manipulation technologies, bringing us closer to the point where genes can be modified in vivo.

1 Aug 2024

Researchers develop highly reactive RNA building blocks for enhanced chip production

An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient. The results of the research were recently published in the prestigious journal Science Advances.

1 Aug 2024

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

TMDU researchers demonstrate proof of concept of antisense nucleic acid therapy to prevent the spread of α-synuclein pathologies in synucleinopathies.

25 Jul 2024

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Researchers compared the distribution of sialic acid receptors in the respiratory tract and mammary glands of dairy cattle naturally infected with the highly pathogenic avian influenza A(H5N1) virus.

18 Jul 2024

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network.

10 Jul 2024

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Researchers trace the 60-year evolution of lipid nanoparticles (LNPs) for nucleic acid delivery, highlighting their potential to revolutionize gene therapy with safer and more effective treatments.

10 Jul 2024

INTEGRA Biosciences’ pipettes help to cultivate success in agriculture

The National Agricultural Research and Development Institute (NARDI) in Fundulea, Romania, relies on electronic multichannel pipettes from INTEGRA Biosciences to streamline its liquid handling workflows.

From INTEGRA Biosciences 9 Jul 2024

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading.

2 Jul 2024

Low-cost CRISPR-based paper strip test offers rapid influenza diagnosis

Fewer than one percent of people who get the flu every year get tested, in part because most tests require trained personnel and expensive equipment.

21 Jun 2024

New method developed for target DNA sequence amplification, testing and analysis

A team of researchers from the Case Western Reserve University School of Medicine has developed a new method for target DNA sequence amplification, testing and analysis.

5 Jun 2024

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Researchers discovered a rare telomere mutation (TTAGGT) in a family, revealing that human telomeres can tolerate non-canonical sequences, impacting telomere maintenance and disease.

4 Jun 2024

FDA urged to relax decades-old tissue donation restrictions for gay and bisexual men

The federal government in 2020 and 2023 changed who it said could safely donate organs and blood, reducing the restrictions on men who have had sex with another man.

24 May 2024

New genetic discoveries offer hope for targeted lupus therapies

Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient's immune system - a therapy that has its own serious risks.

23 May 2024

RedShiftBio launches Aurora TX: Revolutionizing RNA and protein analysis with ultra-sensitive microfluidic modulation spectroscopy and thermal ramping capability

RedShiftBio, a leader in innovative biophysical characterization and bioprocess analytical solutions, proudly announces the launch of Aurora TX at The Protein & Antibody Engineering Summit (PEGS), kicking off on May 13, 2024, in Boston, MA. Aurora TX is the company's latest, most advanced instrument featuring ground-breaking MMS technology, and sets a new standard in biomolecular analysis by providing ultra-sensitive, ultra-precise measurements of biomolecule structure and stability, now enhanced with the addition of thermal ramping capability.

From RedShiftBio 16 May 2024