Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Study reveals ATM kinase as the key driver of replicative senescence

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the protective caps at the chromosome ends-those caps eventually become too short to prevent chromosome ends from being recognized as DNA breaks.

1 Dec 2025

Shared genetic roots between delirium and Alzheimer’s disease

This study reveals genetic and proteomic risk factors for delirium, offering insights into its etiology and potential biomarkers for prediction and prevention.

26 Nov 2025

Immune system abnormalities identified as core mechanism in major depressive disorder

Major depressive disorder (MDD) is characterized by a lowered mood and loss of interest, contributing not only to difficulties in academic and professional life but also as a major cause of suicide in South Korea.

21 Nov 2025

Eating lean beef as part of MED diet could improve gut diversity

Incorporating lean beef into a Mediterranean diet reduces TMAO levels and improves gut health, highlighting the importance of dietary patterns for wellness.

21 Nov 2025

Preclinical study shows aged garlic extract improves memory and reduces anxiety

Long-term aged garlic extract supplementation improved specific anxiety-related behaviors and enhanced memory and learning in aging mice. Proteomic profiling revealed extensive hippocampal and cortical molecular changes linked to synaptic signaling, neuroplasticity, and stress-response pathways.

16 Nov 2025

Bruker announces advancements in immunopeptidomics, de novo PTM analysis, and proteoform profiling

international HUPO, Bruker Corporation today announced new machine learning additions to Bruker ProteoScape™ software for immunopeptidomics and PTM analysis.

From Bruker Daltonics 14 Nov 2025

Evosep unveils open innovation initiative to expand standardization in proteomics

Evosep, a global leader in proteomics solutions, is proud to announce a new initiative at HUPO 2025 aimed at solving one of LCMS based proteomics most persistent challenges: sample preparation.

From Evosep 13 Nov 2025

Bringing accessible NGS-based proteomics to even more labs

At Olink, our mission has always been clear: to make high-quality proteomics accessible to every lab.

From Olink®- Part of Thermo Fisher Scientific 13 Nov 2025

MGI Tech joins forces with SAMRC and DSTI to launch South Africa’s 110K Human Genome Program and unveil Africa’s first DNBSEQ-T7, ushering in a new era in African genomics

The DNBSEQ-T7 sequencing platform and 110K Human Genome Program are transforming South Africa's genomic landscape, promoting local expertise and health equity.

From MGI 11 Nov 2025

Oxidative stress linked to repetitive behaviors in mice

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published November 5, 2025, in the open-access journal PLOS One by Kendall Coden and Dr. Joseph Garner of Stanford University, U.S.

5 Nov 2025

St. Jude scientists identify new therapeutic target for high-risk pediatric leukemia

Acute myeloid leukemia driven by tandem duplications within the UBTF gene (UBTF-TD AML) is a high-risk pediatric cancer in urgent need of novel therapeutic options.

3 Nov 2025

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Researchers identified five previously unknown genes linked to obesity by analyzing rare protein-truncating variants across six ancestries. The study reveals how rare and common genetic factors combine to influence BMI and related diseases like diabetes and heart failure.

2 Nov 2025

Massive cross-ancestry study explains why obesity risks differ around the world

A massive cross-ancestry genetic study involving over 839,000 adults identified 13 genes linked to obesity, including five never before associated with the condition. The findings highlight how global genetic diversity can uncover new biological pathways and potential treatment targets for obesity.

31 Oct 2025

Liver alterations associated with MASLD can directly affect the brain and behavior

A multidisciplinary research team has discovered that liver alterations associated with metabolic dysfunction-associated fatty liver disease (MASLD) can directly cause cognitive and neurological impairments, and that these effects can be reversed by a therapy exclusively targeting the liver.

30 Oct 2025

Understanding age-related changes in T cells and vaccine response

As flu season approaches and public health officials roll out their annual push for vaccination, Allen Institute scientists are learning why vaccines can trigger a weaker response in older adults, around age 65, and what can be done to improve them.

29 Oct 2025

New study reveals how the glucocorticoid receptor forms complex structures inside cells

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

27 Oct 2025

Researchers engineer a tool to dismantle cancer's RNA-built growth hubs

In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of fueling progress, they supercharge disease. That's what researchers at the Texas A&M University Health Science Center (Texas A&M Health) have discovered inside the cells of a rare and aggressive kidney cancer.

21 Oct 2025

Pioneering personalized medicine by deciphering depression's complex biological web

In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Najaf Amin unveils transformative insights that fundamentally reshape international understanding of depression genetics.

15 Oct 2025

Western diet fuels IBD by derailing the microbiome - can precision nutrition turn the tide?

This review examines how Western dietary patterns, high in ultra-processed foods, salt, and unhealthy fats, disrupt gut microbiota, impair immune regulation, and contribute to the global rise of inflammatory bowel disease (IBD). It highlights systems biology and nutritional epidemiology as essential tools to develop personalised dietary strategies and shift IBD care from treatment to prevention.

12 Oct 2025

New blood atlas reveals how diseases leave unique protein signatures

A new study has mapped the distinct molecular "fingerprints" that 59 diseases leave in an individual's blood protein – which would enable blood tests to discern troubling signs from those that are more common.

9 Oct 2025

Proteomics News and Research

Further Reading

Study reveals ATM kinase as the key driver of replicative senescence

Shared genetic roots between delirium and Alzheimer’s disease

Immune system abnormalities identified as core mechanism in major depressive disorder

Eating lean beef as part of MED diet could improve gut diversity

Preclinical study shows aged garlic extract improves memory and reduces anxiety

Bruker announces advancements in immunopeptidomics, de novo PTM analysis, and proteoform profiling

Evosep unveils open innovation initiative to expand standardization in proteomics

Bringing accessible NGS-based proteomics to even more labs

MGI Tech joins forces with SAMRC and DSTI to launch South Africa’s 110K Human Genome Program and unveil Africa’s first DNBSEQ-T7, ushering in a new era in African genomics

Oxidative stress linked to repetitive behaviors in mice

St. Jude scientists identify new therapeutic target for high-risk pediatric leukemia

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Massive cross-ancestry study explains why obesity risks differ around the world

Liver alterations associated with MASLD can directly affect the brain and behavior

Understanding age-related changes in T cells and vaccine response

New study reveals how the glucocorticoid receptor forms complex structures inside cells

Researchers engineer a tool to dismantle cancer's RNA-built growth hubs

Pioneering personalized medicine by deciphering depression's complex biological web

Western diet fuels IBD by derailing the microbiome - can precision nutrition turn the tide?

New blood atlas reveals how diseases leave unique protein signatures

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