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UC San Diego to conduct first U.S. clinical trial of intravenously administered bacteriophage therapy

The U.S. Food and Drug Administration has accepted an Investigational New Drug application by physician-scientists at University of California San Diego School of Medicine to conduct the first U.S. clinical trial of an intravenously administered bacteriophage-based therapy.

9 Jan 2019

Study shows septin proteins detect and kill gut pathogen, Shigella

Using state-of-the art technologies to image human cells and study infection at the level of a single bacterial cell, the research team, led by the London School of Hygiene & Tropical Medicine, has uncovered the strongest evidence yet that septins take Shigella prisoner.

13 Dec 2018

Boosting our defenses to fight Klebsiella infections

Although a relatively common infection, some bacteria that causes pneumonia can be particularly deadly. As a case in point, take Klebsiella pneumoniae, which has been included on the World Health Organisation’s (WHO) list of infections that desperately need new treatments.

6 Dec 2018

Scientists move closer to gonorrhea vaccine after large-scale proteomic study

In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs.

8 Nov 2018

Antibiotic resistance likely to kill 2.4 million across Europe, Australia and North America by 2050

Antibiotic resistance is one of the hottest concerns worldwide today and is likely to take back the human civilization to the pre-antibiotic era at this rate. A new report titled “Stemming the Superbug Tide”, has speculated that antibiotic resistant bugs are soon likely to kill over 90,000 Britons over the next three decades if it is not curbed now.

7 Nov 2018

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

Researchers from the Molecular Biology Institute of Barcelona and the Institute of Biotechnology and Biomedicine have discovered the mechanism by which the bacterium Mycoplasma genitalium) adheres to human cells.

29 Oct 2018

ANTRUK’s Annual Lecture sends out message on shortage of funds for antibiotic research

A national charity will use the 90th anniversary of the discovery of penicillin to call for a massive injection of funds into antibiotic research - or risk returning humanity to an age where people died from something as simple as a scratch.

17 Oct 2018

Doctors use bacteriophages to treat patient with multi-drug resistant bacterial infection

The married professors were spending their Thanksgiving holiday in Egypt when the husband, Thomas L. Patterson, Ph.D., got very sick very quickly, experiencing fever, nausea and a racing heartbeat. By the time Patterson was accurately diagnosed with a highly multi-drug resistant bacterial infection, he was near death.

4 Oct 2018

Superbugs emerging from skin bacteria on the increase

A new study has shown that some of the sub-strains of the bacteria that commonly live on our skin have become resistant to common infections – or in other words turned into superbugs. Infections with these strains thus could become untreatable with the antibiotics available and may turn life-threatening, warn researchers.

6 Sep 2018

UH researchers win $3.5 million grant to develop technology that combats multi-drug resistant bacteria

Two UH researchers have won a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases to develop technology that will quickly suggest the most promising combinations of antibiotics to kill certain resistant bacteria.

30 Aug 2018

UC San Diego launches new bacteriophage therapy center

With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America's first Center for Innovative Phage Applications and Therapeutics

22 Jun 2018

Researchers isolate bacteria that pose triple threat from a patient in the U.S.

Researchers from the Emory Antibiotic Resistance Center describe the first strain of carbapenem-resistant, hypermucoviscous Klebsiella pneumoniae exhibiting colistin heteroresistance and enhanced virulence isolated from a patient in the United States.

11 Jun 2018

Bacterium causing nosocomial infections uses tiny finger-like structures to infect medical tools

The antibiotic-resistant Acinetobacter baumannii bacterium is one of the most globally harmful bacteria that causes nosocomial infections.

1 Jun 2018

New lab-based approach shows how microbes can work with hosts to prevent infection

The benefits of antibiotics to both human and animal health are undisputed. However, as microbes have become increasingly resistant to antimicrobials and other drugs, scientists have become interested in new solutions to the growing superbug crisis, including the use of defensive microbes and faecal transplants.

29 May 2018

Drug-resistant staph infections found to be deadly, but less costly

Staph infections, whether MRSA (resistant to methicillin) or susceptible, are important and deadly. Drug-resistant staph infections continue to be deadlier than those that are not resistant and treatable with traditional antibiotics, but treatment costs surprisingly are the same or slightly less, a new national analysis shows.

15 May 2018

Study: Nearly three-quarters of commonly used medical scopes tainted by bacteria

In an ominous sign for patient safety, 71 percent of reusable medical scopes deemed ready for use on patients tested positive for bacteria at three major U.S. hospitals, according to a new study.

23 Apr 2018

Researchers discover highly antibiotic resistant superbugs in Gulf States

A new wave of highly antibiotic resistant superbugs has been found in the Middle East Gulf States, discovered by University of Queensland researchers.

19 Apr 2018

Monash scientists discover how gonorrhea-causing superbug evades the immune system

Every year, more than 100 million people worldwide develop the sexually transmitted disease gonorrhea, with health consequences such as infertility, transmission of the disease to newborn babies, and increased risk of HIV infections. There has been a 63 percent rise in gonorrhea in Australia over the past five years.

30 Mar 2018

Super-gonorrhea bug infects UK man

A man from United Kingdom has acquired a gonorrhea infection with bacteria that is resistant to most antibiotics used commonly against it. The man has a regular sexual partner but picked up this superbug from a sexual encounter with a partner in south-east Asia earlier this year.

29 Mar 2018

Scientists create synthesized antibiotic capable of treating superbugs

A "game changing" new antibiotic which is capable of killing superbugs has been successfully synthesized and used to treat an infection for the first time -- and could lead to the first new class of antibiotic drug in 30 years.

23 Mar 2018